Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S. Melkorka Maggadottir"'
Autor:
S. Melkorka Maggadottir, Xiao Chang, Akshatha Desai, Yun Li, Jin Li, Hakon Hakonarson, Zhi Wei
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1860:2656-2663
Background Common variable immunodeficiency disorder (CVID) is the most frequently encountered symptomatic primary immunodeficiency, characterized by highly heterogeneous immunological features and clinical presentations. As better targeted therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1504a26ffeeaaed30d4a55e276ea02
https://doi.org/10.1016/j.bbagen.2016.06.014
https://doi.org/10.1016/j.bbagen.2016.06.014
Purpose of review Food allergy is common among children and adults worldwide. Recent studies have improved our understanding of the genetic mechanism of food allergy and further studies may result in clinical application through genetic testing. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f408f2455508588530e8499353f36ff0
https://europepmc.org/articles/PMC5407010/
https://europepmc.org/articles/PMC5407010/
Autor:
James T. Elder, Rajan P. Nair, Klaus Warnatz, Marina Bakay, Rahul Pandey, Stephan Brand, Børre Fevang, Reinhold E. Schmidt, Joseph T. Glessner, Bodo Grimbacher, Kathleen E. Sullivan, S. Melkorka Maggadottir, Wolfgang Lieb, Faranaz Atschekzei, Tom H. Karlsen, Silje F. Jørgensen, Markus M. Nöthen, Elena S. Resnick, Eva Ellinghaus, Christian Gieger, Ulrich Salzer, Mary Buchta, Jin Li, Torsten Witte, Lennart Hammarström, Trine Folseraas, Vibeke Videm, Andre Franke, Jordan S. Orange, Helen Chapel, Stefan Schreiber, Carsten Büning, Pål Aukrust, Hakon Hakonarson, Juliane Winkelmann, Elena E. Perez, Leonid Padyukov, Sigune Goldacker, Charlotte Cunningham-Rundles
Publikováno v:
Nature communications
Common variable immunodeficiency disorder (CVID) is the most common symptomatic primary immunodeficiency in adults, characterized by B-cell abnormalities and inadequate antibody response. CVID patients have considerable autoimmune comorbidity and we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52203ad43f91e938cdb90c0113a0dae
https://mediatum.ub.tum.de/doc/1349588/document.pdf
https://mediatum.ub.tum.de/doc/1349588/document.pdf
Autor:
Yan Zhao, Fengxiang Wang, Zhi Wei, Silje F. Jørgensen, Elena E. Perez, Cecilia E. Kim, Tom H. Karlsen, Helen Chapel, Xiao Chang, Kathleen E. Sullivan, Cuiping Hou, Joseph T. Glessner, Jordan S. Orange, Frank D. Mentch, Charlotte Cunningham-Rundles, Hakon Hakonarson, S. Melkorka Maggadottir, Kelly A. Thomas, Jin Li, Yun Li
Background Common variable immunodeficiency (CVID) is characterized clinically by inadequate quantity and quality of serum immunoglobulins with increased susceptibility to infections, resulting in significant morbidity and mortality. Only a few genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4220a42ef3dfd66e9993f16d458d178
https://europepmc.org/articles/PMC4461447/
https://europepmc.org/articles/PMC4461447/
Autor:
Jin Li, Patrick M. A. Sleiman, Rosetta M. Chiavacci, Dimitri S. Monos, Fengxiang Wang, Zhi Wei, Jane E Munro, Edward M. Behrens, Carol Wise, Kathleen E. Sullivan, Jack Satsangi, Jordan S. Orange, Sihai Dave Zhao, Subramaniam Kugathasan, Maede Mohebnasab, Vito Annese, Elena S. Resnick, Charlotte Cunningham-Rundles, Eline T. Luning Prak, Constantin Polychronakos, Christopher J. Cardinale, Haijun Qui, Kelly A. Thomas, David C. Wilson, Cecilia E. Kim, Yiran Guo, Marina Bakay, Julie Kobie, Brendan J. Keating, Elena E. Perez, Frank D. Mentch, Marla Dubinsky, Richard K Russell, Hakon Hakonarson, Stephen L. Guthery, Berit Flatø, Justine A. Ellis, Susan D. Thompson, Struan F.A. Grant, Øystein Førre, James Snyder, Benedicte A. Lie, Marilynn Punaro, Erasmo Miele, Yun Li, Mara L. Becker, Debra J. Abrams, S. Melkorka Maggadottir, Annamaria Staiano, Caterina Strisciuglio, Lee A. Denson, Terri H. Finkel, John Connolly, Dong Li, Hongzhe Li, Helen Chapel, Robert N. Baldassano, Anne M. Griffiths, Anna Latiano, Mark S. Silverberg, Jonathan P. Bradfield, Laura Steel, Joseph T. Glessner
Publikováno v:
Nature Communications
Li, Y R, Zhao, S D, Li, J, Bradfield, J P, Mohebnasab, M, Steel, L, Kobie, J, Abrams, D J, Mentch, F D, Glessner, J T, Guo, Y, Wei, Z, Connolly, J J, Cardinale, C J, Bakay, M, Li, D, Maggadottir, S M, Thomas, K A, Qui, H, Chiavacci, R M, Kim, C E, Wang, F, Snyder, J, Flatø, B, Førre, Ø, Denson, L A, Thompson, S D, Becker, M L, Guthery, S L, Latiano, A, Perez, E, Resnick, E, Strisciuglio, C, Staiano, A, Miele, E, Silverberg, M S, Lie, B A, Punaro, M, Russell, R K, Wilson, D C, Dubinsky, M C, Monos, D S, Annese, V, Munro, J E, Wise, C, Chapel, H, Cunningham-Rundles, C, Orange, J S, Behrens, E M, Sullivan, K E, Kugathasan, S, Griffiths, A M, Satsangi, J, Grant, S F A, Sleiman, P M A, Finkel, T H, Polychronakos, C, Baldassano, R N, Luning Prak, E T, Ellis, J A, Li, H, Keating, B J & Hakonarson, H 2015, ' Genetic sharing and heritability of paediatric age of onset autoimmune diseases ', Nature Communications, vol. 6, pp. 8442 . https://doi.org/10.1038/ncomms9442
Li, Y R, Zhao, S D, Li, J, Bradfield, J P, Mohebnasab, M, Steel, L, Kobie, J, Abrams, D J, Mentch, F D, Glessner, J T, Guo, Y, Wei, Z, Connolly, J J, Cardinale, C J, Bakay, M, Li, D, Maggadottir, S M, Thomas, K A, Qui, H, Chiavacci, R M, Kim, C E, Wang, F, Snyder, J, Flatø, B, Førre, Ø, Denson, L A, Thompson, S D, Becker, M L, Guthery, S L, Latiano, A, Perez, E, Resnick, E, Strisciuglio, C, Staiano, A, Miele, E, Silverberg, M S, Lie, B A, Punaro, M, Russell, R K, Wilson, D C, Dubinsky, M C, Monos, D S, Annese, V, Munro, J E, Wise, C, Chapel, H, Cunningham-Rundles, C, Orange, J S, Behrens, E M, Sullivan, K E, Kugathasan, S, Griffiths, A M, Satsangi, J, Grant, S F A, Sleiman, P M A, Finkel, T H, Polychronakos, C, Baldassano, R N, Luning Prak, E T, Ellis, J A, Li, H, Keating, B J & Hakonarson, H 2015, ' Genetic sharing and heritability of paediatric age of onset autoimmune diseases ', Nature Communications, vol. 6, pp. 8442 . https://doi.org/10.1038/ncomms9442
Autoimmune diseases (AIDs) are polygenic diseases affecting 7–10% of the population in the Western Hemisphere with few effective therapies. Here, we quantify the heritability of paediatric AIDs (pAIDs), including JIA, SLE, CEL, T1D, UC, CD, PS, SPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09472a3d4f3f7560a68b3c98bd00086e
http://hdl.handle.net/11591/371032
http://hdl.handle.net/11591/371032
Autor:
Marina Bakay, Diana Chang, Kelly A. Thomas, Jack Satsangi, Sihai Dave Zhao, Cuiping Hou, Carol Wise, Dong Li, Feng Gao, Anne M. Griffiths, Brendan J. Keating, Jane E Munro, Jin Li, Berit Flatø, Øystein Førre, Marla Dubinsky, Benedicte A. Lie, Charlotte Cunningham-Rundles, Erasmo Miele, Debra J. Abrams, Elena S. Resnick, Edward M. Behrens, Haijun Qiu, Marilynn Punaro, Anna Latiano, Alon Keinan, David C. Wilson, Christopher J. Cardinale, John Connolly, Lee A. Denson, Mark S. Silverberg, Subra Kugathasan, Jonathan P. Bradfield, Dimitri S. Monos, Fengxiang Wang, Richard K Russell, Annamaria Staiano, Hakon Hakonarson, Caterina Strisciuglio, Justine A. Ellis, Stephen L. Guthery, Hongzhe Li, Terri H. Finkel, Helen Chapel, Marylyn D Richie, James Snyder, S. Melkorka Maggadottir, Elena E. Perez, Rosetta M. Chiavacci, Kathleen E. Sullivan, Struan F.A. Grant, Robert N. Baldassano, Jordan S. Orange, Eline T. Luning Prak, Vito Annese, Constantin Polychronakos, Cecilia E. Kim, Yiran Guo, Frank D. Mentch, Susan D. Thompson, Charlly Kao, Yun Li, Mara L. Becker, Zhi Wei, Joseph T. Glessner, Patrick M. A. Sleiman
Publikováno v:
Li, Y R, Li, J, Zhao, S D, Bradfield, J P, Mentch, F D, Maggadottir, S M, Hou, C, Abrams, D J, Chang, D, Gao, F, Guo, Y, Wei, Z, Connolly, J J, Cardinale, C J, Bakay, M, Glessner, J T, Li, D, Kao, C, Thomas, K A, Qiu, H, Chiavacci, R M, Kim, C E, Wang, F, Snyder, J, Richie, M D, Flatø, B, Førre, Ø, Denson, L A, Thompson, S D, Becker, M L, Guthery, S L, Latiano, A, Perez, E, Resnick, E, Russell, R K, Wilson, D C, Silverberg, M S, Annese, V, Lie, B A, Punaro, M, Dubinsky, M C, Monos, D S, Strisciuglio, C, Staiano, A, Miele, E, Kugathasan, S, Ellis, J A, Munro, J E, Sullivan, K E, Wise, C A, Chapel, H, Cunningham-Rundles, C, Grant, S F A, Orange, J S, Sleiman, P M A, Behrens, E M, Griffiths, A M, Satsangi, J, Finkel, T H, Keinan, A, Prak, E T L, Polychronakos, C, Baldassano, R N, Li, H, Keating, B J & Hakonarson, H 2015, ' Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases ', Nature Medicine, vol. 21, no. 9, pp. 1018-27 . https://doi.org/10.1038/nm.3933
Genome-wide association studies (GWASs) have identified hundreds of susceptibility genes, including shared associations across clinically distinct autoimmune diseases. We performed an inverse χ(2) meta-analysis across ten pediatric-age-of-onset auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a664397189da098ac93eca4cafa6cef7
http://hdl.handle.net/11591/371028
http://hdl.handle.net/11591/371028