Zobrazeno 1 - 10
of 150
pro vyhledávání: '"S. McKim"'
Autor:
Siqi Sun, Tyler Defosse, Ayla Boyd, Joel Sop, Faith Verderose, Diya Surray, Mark Aziz, Margaret Howland, Siwen Wu, Neha Changela, Janet Jang, Karen Schindler, Jinchuan Xing, Kim S. McKim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Reproductive success requires the development of viable oocytes and the accurate segregation of chromosomes during meiosis. Failure to segregate chromosomes properly can lead to infertility, miscarriages, or developmental disorders. A variet
Externí odkaz:
https://doaj.org/article/d2a7704538b04f7ea7b17679a0f73844
Autor:
Jessica E Fellmeth, Janet K Jang, Manisha Persaud, Hannah Sturm, Neha Changela, Aashka Parikh, Kim S McKim
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011066 (2023)
The centromere is an epigenetic mark that is a loading site for the kinetochore during meiosis and mitosis. This mark is characterized by the H3 variant CENP-A, known as CID in Drosophila. In Drosophila, CENP-C is critical for maintaining CID at the
Externí odkaz:
https://doaj.org/article/1e7e3263e7f1401ca9f5eff0ab0ca6f6
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 5, Pp 1555-1569 (2018)
Bipolar spindle assembly occurs in the absence of centrosomes in the oocytes of most organisms. In the absence of centrosomes in Drosophila oocytes, we have proposed that the kinesin 6 Subito, a MKLP-2 homolog, is required for establishing spindle bi
Externí odkaz:
https://doaj.org/article/9d44b3ae125746afa56c3b25653fed2b
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008072 (2019)
Sister centromere fusion is a process unique to meiosis that promotes co-orientation of the sister kinetochores, ensuring they attach to microtubules from the same pole during metaphase I. We have found that the kinetochore protein SPC105R/KNL1 and P
Externí odkaz:
https://doaj.org/article/cca2e6c9263a4aacbeebca8c809b080d
Autor:
Cathleen M Lake, Rachel J Nielsen, Amanda M Bonner, Salam Eche, Sanese White-Brown, Kim S McKim, R Scott Hawley
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007886 (2019)
Meiotic recombination, which is necessary to ensure that homologous chromosomes segregate properly, begins with the induction of meiotic DNA double-strand breaks (DSBs) and ends with the repair of a subset of those breaks into crossovers. Here we inv
Externí odkaz:
https://doaj.org/article/4d881041bc1e449884e0c76903ae472f
Autor:
Siqi Sun, Tyler Defosse, Ayla Boyd, Joel Sop, Faith Verderose, Diya Surray, Mark Aziz, Margaret Howland, Siwen Wu, Neha Changela, Janet Jang, Karen Schindler, Jinchuan Xing, Kim S. McKim
Reproductive success requires the development of viable oocytes and the accurate segregation of chromosomes during meiosis. Failure to segregate chromosomes properly can lead to infertility, miscarriages, or developmental disorders. A variety of fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56c7c384d8fdddd1db85d00f9ed25138
https://doi.org/10.1101/2023.05.12.540472
https://doi.org/10.1101/2023.05.12.540472
Autor:
Jessica E. Fellmeth, Hannah Sturm, Janet Jang, Neha Changela, Aashka Parikh, Manisha Persaud, Kim S. McKim
Publikováno v:
bioRxiv
SummaryThe centromere is an epigenetic mark that is a loading site for the kinetochore during meiosis and mitosis. This mark is characterized by the H3 variant CENP-A, known as CID inDrosophila, which replaces canonical H3 at the centromeres. InDroso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737fe1c13a8bc2a51a1871a5f578dfc4
https://europepmc.org/articles/PMC10054979/
https://europepmc.org/articles/PMC10054979/
Akademický článek
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Autor:
E. Kane, N. Farruggio, S. Perez, S. McKim, D. Johnston, Margaret J. Schwab, Jerald A. Brotzge, Jeffrey Freedman, Everette Joseph, K. Hemker, John W. Sicker, N. Bassill, Justin R. Minder, James J. Schwab, P. Naple, Junhong Wang, N. Bain, C. D. Thorncroft, Scott D. Miller
Publikováno v:
Journal of Atmospheric and Oceanic Technology. 37:1827-1845
The New York State Mesonet (NYSM) is a network of 126 standard environmental monitoring stations deployed statewide with an average spacing of 27 km. The primary goal of the NYSM is to provide high-quality weather data at high spatial and temporal sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d49310f970216f4c0fc95c98318666b
https://doi.org/10.1175/jtech-d-19-0220.1
https://doi.org/10.1175/jtech-d-19-0220.1
Autor:
Jessica E. Fellmeth, Kim S. McKim
Publikováno v:
Essays Biochem
While many of the proteins involved in the mitotic centromere and kinetochore are conserved in meiosis, they often gain a novel function due to the unique needs of homolog segregation during meiosis I (MI). CENP-C is a critical component of the centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed609e548b374fb5113c477bf136bb5
https://doi.org/10.1042/ebc20190080
https://doi.org/10.1042/ebc20190080