Zobrazeno 1 - 10
of 358
pro vyhledávání: '"S. McClain"'
Autor:
J. H. Akkerdaas, A. Cianferoni, E. Islamovic, J. Kough, G. S. Ladics, S. McClain, L. K. Poulsen, A. Silvanovich, L. Pereira Mouriès, R. van Ree
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
BackgroundProtease resistance is considered a risk factor for allergenicity of proteins, although the correlation is low. It is nonetheless a part of the weight-of-evidence approach, proposed by Codex, for assessing the allergenicity risk of novel fo
Externí odkaz:
https://doaj.org/article/785d74f714f547aca1810c7dd53b93eb
Autor:
Lee C. Brackman, Matthew S. Jung, Emily H. Green, Nikhita Joshi, Frank L. Revetta, Mark S. McClain, Nicholas O. Markham, M. Blanca Piazuelo, Holly M. Scott Algood
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Helicobacter pylori infection is the predominant risk factor for the development of gastric cancer. Risk is enhanced by specific H. pylori virulence factors, diet, and the inflammatory response. Chronic activation of T helper (Th) 1 and Th17 pathways
Externí odkaz:
https://doaj.org/article/03dbf62ffce94765a96b6d5966c7825c
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 5 (2024)
ABSTRACTBacterial lipoproteins are post-translationally modified by the addition of acyl chains that anchor the protein to bacterial membranes. This modification includes two ester-linked and one amide-linked acyl chain on lipoproteins from Gram-nega
Externí odkaz:
https://doaj.org/article/6285190e5c774bb3967e4510ae61b980
Autor:
Jennifer H. B. Shuman, Aung Soe Lin, Mandy D. Westland, Kaeli N. Bryant, M. Blanca Piazuelo, Michelle L. Reyzer, Audra M. Judd, W. Hayes McDonald, Mark S. McClain, Kevin L. Schey, Holly M. S. Algood, Timothy L. Cover
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTHelicobacter pylori colonization of the human stomach is a strong risk factor for gastric cancer. To investigate H. pylori-induced gastric molecular alterations, we used a Mongolian gerbil model of gastric carcinogenesis. Histologic evaluatio
Externí odkaz:
https://doaj.org/article/7753176891d94092ac155dd69412c031
Autor:
Dusty R. Miller, Ethan S. McClain, James N. Dodds, Andrzej Balinski, Jody C. May, John A. McLean, David E. Cliffel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Despite the significant progress in both scientific understanding and regulations, the safety of agricultural pesticides continues to be called into question. The need for complementary analytics to identify dysregulation events associated with chemi
Externí odkaz:
https://doaj.org/article/004f0b9524ec4a3987f75b863dcd5caf
Autor:
Aung Soe Lin, Mark S. McClain, Amber C. Beckett, Rhonda R. Caston, M. Lorena Harvey, Beverly R. E. A. Dixon, Anne M. Campbell, Jennifer H. B. Shuman, Neha Sawhney, Alberto G. Delgado, John T. Loh, M. Blanca Piazuelo, Holly M. Scott Algood, Timothy L. Cover
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT The Helicobacter pylori Cag type IV secretion system (T4SS) translocates the effector protein CagA and nonprotein bacterial constituents into host cells. In this study, we infected Mongolian gerbils with an H. pylori strain in which expressi
Externí odkaz:
https://doaj.org/article/3791960f61674d22a55ee21aa1db0972
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Our current understanding of lipoprotein synthesis and localization in Gram-negative bacteria is based primarily on studies of Escherichia coli. Newly synthesized E. coli prolipoproteins undergo posttranslational modifications catalyzed by t
Externí odkaz:
https://doaj.org/article/6ebec5b28d944ceb84558e28b4a91e4a
Publikováno v:
Journal of Bacteriology. 205
Lipoproteins are critical in Gram-negative-bacteria for cell surface assembly of LPS, insertion of outer membrane proteins, and sensing envelope stress. Lipoproteins also contribute to bacterial pathogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::600d55443ce31e6eb12da4ac0dedca08
https://doi.org/10.1128/jb.00052-23
https://doi.org/10.1128/jb.00052-23
Publikováno v:
Label-free Biomedical Imaging and Sensing (LBIS) 2023.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88bf00d00d0a0fa15aa41678cc07fa71
https://doi.org/10.1117/12.2650783
https://doi.org/10.1117/12.2650783
Autor:
John T. Loh, Emily L. Struttmann, Natalie Favret, M. Lorena Harvey, Suman B. Pakala, Abha Chopra, Mark S. McClain, Timothy L. Cover
Publikováno v:
Infection and Immunity. 91
Both Helicobacter pylori infection and a high-salt diet are risk factors for gastric cancer. We previously showed that a mutation in fur (encoding the ferric uptake regulator variant Fur-R88H) was positively selected in H. pylori strains isolated fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608f9f539934442e9c4f7aba08d130ff
https://doi.org/10.1128/iai.00420-22
https://doi.org/10.1128/iai.00420-22