Zobrazeno 1 - 10
of 373
pro vyhledávání: '"S. Matheson"'
Publikováno v:
Animal, Vol 3, Iss 11, Pp 1555-1561 (2009)
The experiment measured lamb responses to supplementation of the pregnant ewe diet with vitamin E above requirement. Crossbred ewes were mated with either Suffolk or Texel rams. Twin-bearing ewes were randomly allocated (approximately 21 months of ag
Externí odkaz:
https://doaj.org/article/9cfb190e443c49e88eedf4f4d7a2429c
Autor:
Fiamma Salerno, Andrew J. M. Howden, Louise S. Matheson, Özge Gizlenci, Michael Screen, Holger Lingel, Monika C. Brunner-Weinzierl, Martin Turner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract During B cell maturation, transitional and mature B cells acquire cell-intrinsic features that determine their ability to exit quiescence and mount effective immune responses. Here we use label-free proteomics to quantify the proteome of B c
Externí odkaz:
https://doaj.org/article/a73a6dd20eda46d58f1c7c4fa5d6a06d
Autor:
Olga Mielczarek, Carolyn H. Rogers, Yinxiu Zhan, Louise S. Matheson, Michael J.T. Stubbington, Stefan Schoenfelder, Daniel J. Bolland, Biola M. Javierre, Steven W. Wingett, Csilla Várnai, Anne Segonds-Pichon, Simon J. Conn, Felix Krueger, Simon Andrews, Peter Fraser, Luca Giorgetti, Anne E. Corcoran
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113074- (2023)
Summary: To produce a diverse antibody repertoire, immunoglobulin heavy-chain (Igh) loci undergo large-scale alterations in structure to facilitate juxtaposition and recombination of spatially separated variable (VH), diversity (DH), and joining (JH)
Externí odkaz:
https://doaj.org/article/125cbc8ecfba40ce99ab9245a423021d
Autor:
David J Turner, Alexander Saveliev, Fiamma Salerno, Louise S Matheson, Michael Screen, Hannah Lawson, David Wotherspoon, Kamil R Kranc, Martin Turner
Publikováno v:
eLife, Vol 11 (2022)
To identify roles of RNA binding proteins (RBPs) in the differentiation or survival of antibody secreting plasma cells we performed a CRISPR/Cas9 knockout screen of 1213 mouse RBPs for their ability to affect proliferation and/or survival, and the ab
Externí odkaz:
https://doaj.org/article/82d0b3c9007147978c12bb01398d56b3
Autor:
Yoshihiko Yu, Kate L. Shumway, Jodi S. Matheson, Marie E. Edwards, Timothy L. Kline, Leslie A. Lyons
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Approximately 30% of Persian cats have a c.10063C > A variant in polycystin 1 (PKD1) homolog causing autosomal dominant polycystic kidney disease (ADPKD). The variant is lethal in utero when in the homozygous state and is the only
Externí odkaz:
https://doaj.org/article/cdf5f3158f50427a9cb20b1957df3761
Publikováno v:
Reviews in Environmental Science and Bio/Technology. 22:249-280
Poor indoor air quality has become of particular concern within the built environment due to the time people spend indoors, and the associated health burden. Volatile organic compounds (VOCs) off-gassing from synthetic materials, nitrogen dioxide and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58a5ce2bf6b140a3d1b91adb8031d23
https://doi.org/10.1007/s11157-023-09644-5
https://doi.org/10.1007/s11157-023-09644-5
Autor:
Elisa Monzón-Casanova, Louise S Matheson, Kristina Tabbada, Kathi Zarnack, Christopher WJ Smith, Martin Turner
Publikováno v:
eLife, Vol 9 (2020)
Polypyrimidine tract-binding protein 1 (PTBP1) is a RNA-binding protein (RBP) expressed throughout B cell development. Deletion of Ptbp1 in mouse pro-B cells results in upregulation of PTBP2 and normal B cell development. We show that PTBP2 compensat
Externí odkaz:
https://doaj.org/article/b68b2bc2ff684844afe3e2ee6dd99ca4
Autor:
Hashem Koohy, Daniel J. Bolland, Louise S. Matheson, Stefan Schoenfelder, Claudia Stellato, Andrew Dimond, Csilla Várnai, Peter Chovanec, Tamara Chessa, Jeremy Denizot, Raquel Manzano Garcia, Steven W. Wingett, Paula Freire-Pritchett, Takashi Nagano, Phillip Hawkins, Len Stephens, Sarah Elderkin, Mikhail Spivakov, Peter Fraser, Anne E. Corcoran, Patrick D. Varga-Weisz
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-24 (2018)
Abstract Background Aging is characterized by loss of function of the adaptive immune system, but the underlying causes are poorly understood. To assess the molecular effects of aging on B cell development, we profiled gene expression and chromatin f
Externí odkaz:
https://doaj.org/article/6176506a0b014dd1a2e2a5beb2a2e029
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