Zobrazeno 1 - 10
of 433
pro vyhledávání: '"S. Marlow"'
Autor:
John S. Marlow
The U.S. government supports a broad range of scientific and engineering research and development. Its purposes include addressing national defense, health, safety, the environment, and energy security; advancing knowledge generally; developing the U
Autor:
Emine Ozturk, Mengya Zhao, Angelina Joy, Christina S. Marlow, Fidelia Law, Ashley R. Deutsch, Channing J. Mathews, Adam J. Hoffman, Luke McGuire, Mark Winterbottom, Frances Balkwill, Karen Burns, Laurence Butler, Marc Drews, Grace Fields, Hannah Smith, Adam Rutland, Adam Hartstone-Rose, Kelly Lynn Mulvey
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/e395eb93b12345338c5e6f7b014dc298
Autor:
Yanyun Liu, Kenny Tsang, Michelle Mays, Gale Hansen, Jeffrey Chiecko, Maureen Crames, Yangjie Wei, Weijie Zhou, Chase Fredrick, James Hu, Dongmei Liu, Douglas Gebhard, Zhong-Fu Huang, Akshita Datar, Anthony Kronkaitis, Kristina Gueneva-Boucheva, Daniel Seeliger, Fei Han, Saurabh Sen, Srinath Kasturirangan, Justin M. Scheer, Andrew E. Nixon, Tadas Panavas, Michael S. Marlow, Sandeep Kumar
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Biotherapeutic optimization, whether to improve general properties or to engineer specific attributes, is a time-consuming process with uncertain outcomes. Conversely, Consensus Protein Design has been shown to be a viable approach to enhance protein
Externí odkaz:
https://doaj.org/article/4c91351f25cc410584aa768aeb4853a4
Publikováno v:
mAbs, Vol 11, Iss 7, Pp 1319-1330 (2019)
Biotherapeutic proteins are commonly dosed at high concentrations into the blood, which is an inherently complex, crowded solution with substantial protein content. The effects of macromolecular crowding may lead to an appreciable level of non-specif
Externí odkaz:
https://doaj.org/article/ebaeebd8830d4c89a466b109c218b558
Autor:
Sandro Halwe, Alexandra Kupke, Kanika Vanshylla, Falk Liberta, Henning Gruell, Matthias Zehner, Cornelius Rohde, Verena Krähling, Michelle Gellhorn Serra, Christoph Kreer, Michael Klüver, Lucie Sauerhering, Jörg Schmidt, Zheng Cai, Fei Han, David Young, Guangwei Yang, Marek Widera, Manuel Koch, Anke Werner, Lennart Kämper, Nico Becker, Michael S. Marlow, Markus Eickmann, Sandra Ciesek, Felix Schiele, Florian Klein, Stephan Becker
Publikováno v:
Viruses, Vol 13, Iss 8, p 1498 (2021)
Despite the recent availability of vaccines against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), there is an urgent need for specific anti-SARS-CoV-2 drugs. Monoclonal neutralizing antibodies are an important drug class in the g
Externí odkaz:
https://doaj.org/article/a952a8244dfc4b74bafbb2519784edf5
Akademický článek
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Akademický článek
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Autor:
Giuseppe Licari, Kyle P. Martin, Maureen Crames, Joseph Mozdzierz, Michael S. Marlow, Anne R. Karow-Zwick, Sandeep Kumar, Joschka Bauer
Adequate stability, manufacturability and safety is crucial to bring an antibody-based biotherapeutic to the market. Following the concept of holistic in silico developability, we introduce physicochemical description of 91 market-stage antibody-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc96d7c65fdcd861c25f116c498e7f6
Publikováno v:
Seismological Research Letters. 92:494-507
The Crittenden County fault zone (CCFZ) is a potentially active fault zone located within 25 km of Memphis, Tennessee, and poses a significant seismic hazard to the region. Previous research has associated the fault zone with basement faults of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7263bd7b901718636007b4f82bb7cebb
https://doi.org/10.1785/0220200209
https://doi.org/10.1785/0220200209
Publikováno v:
Journal of pharmaceutical sciences. 111(11)
Over seventy percent of marketed monoclonal antibody therapeutics contain between 0.001% and 0.1% (w/v) polysorbate, as it has a generally beneficial stabilizing effect that increases drug product shelf life. However, polysorbate has also been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddce91116d6d6fa60350a27a7a12aa1c
https://pubmed.ncbi.nlm.nih.gov/35977591
https://pubmed.ncbi.nlm.nih.gov/35977591