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Autor:
S. Manfroi, Emanuela Ottaviani, Sante Tura, Giuseppe Visani, Patrizia Tosi, Alfonso Zaccaria, A. Morelli, R. Zanchini, Anna Lia Molinari, R. Pastano, C. Baccini, C. Remiddi
Publikováno v:
European Journal of Haematology. 57:301-306
Leukemic cells spontaneously secrete cytokines involved in the proliferation of the clone; in this study we evaluated the effects of all-trans retinoic acid (ATRA) on the in vitro autocrine production of cytokines by acute myeloid leukemia cells. Thi
Publikováno v:
European Journal of Haematology. 57:134-141
It has been reported that in vitro prednisolone (PDN) resistance provides a prognostic value in childhood acute lymphoblastic leukaemia (ALL). This study aimed at investigating the biological and clinical significance of in vitro PDN resistance in ad
Publikováno v:
Transfusion Medicine and Hemotherapy. 26:339-343
Background: The efficiency of prestorage leukodepletion of whole blood on the production of proinflammatory cytokines (IL-β, IL-6, IL-8 and TNF-α) was compared i
Autor:
F. Fruet, P. Felleiter, R. Conte, A. Bontadini, J. Freudenberg, H. Storch, J. Zingsem, C. Fleischer, H. Lefèvre, A. Glaser, D. Glück, J.M. Schierholz, H. Fiedler, G. Singbartl, W.H. Gerlich, H. Aicher, C. Kücherer, P. Michel, B. Neidhardt, T. Vuk, S. Manfroi, W. Weise, S.T. Kießig, A. Mühlbacher, C. Hornstein, M. Tomicic, V. Kretschmer, G. Pulverer, R. Eckstein, D. Grgicevic, M.C. Ruscitto, J. Beuth, G. Caspari, C. Saavedra-Maldonado, W. Schleinzer, A.F.E. Rump, V. Weisbach, G. Hunsmann, D. Godec, W. Bodemer, M. Wiesneth, U.T. Seyfert, P. Muß, T. Zeiler, B. Kubanek, U. Michl, C. Stahl-Hennig, R. Zimmermann, M. Balija, G. Pauli, C. Maglov
Publikováno v:
Transfusion Medicine and Hemotherapy. 26:253-257
Autor:
Emanuela Ottaviani, Sante Tura, Patrizia Tosi, Annalisa Pellacani, S. Manfroi, Giuseppe Visani
Publikováno v:
Anti-Cancer Drugs. 7:774-779
All-trans-retinoic acid (ATRA) has proven useful in acute promyelocytic leukemia (APL). In order to reduce the side effects and to improve the efficacy of this compound, conventional chemotherapy, and anthracyclines in particular, are frequently adde
Publikováno v:
Leukemia & Lymphoma. 23:437-442
Pseudotumor cerebri or idiopathic intracranial hypertension is a neurological syndrome characterized by signs and symptoms of intracranial hypertension without clinical and radiological evidence of infective or space occupying lesions. Iatrogenic fac
Autor:
G. Visani, P. Tosi, S. Manfroi, E. Ottaviani, C. Finelli, A. Cenacchi, M. Bendandi, S. Tura, Mashiro Imamura, Masharu Kasai, Xiaofan Zhu, Sumiko Kobayashi, Satoshi Hashino, Toshio Higa, Keisuke Sakurada, Masahiro Asaka
Publikováno v:
Leukemia & Lymphoma. 19:277-280
Myelodysplastic syndromes (MDS) are a group of hematopoietic disorders characterized by uni- or multilineage maturation defects of the bone marrow. Controversial therapeutic results have been obtained using growth factors or differentiating agents su
Autor:
Giorgio Zauli, Patrizia Tosi, Davide Gibellini, Emanuela Ottaviani, Barbara Gamberi, Marco Marchisiot, A. Cenacchi, Giuseppe Visani, Sante Tura, S. Manfroi
Publikováno v:
Leukemia & Lymphoma. 14:503-507
All-trans retinoic acid (ATRA) represents a highly effective treatment for acute promyelocytic leukemia (M3-ANLL). This compound induces the leukemic promyelocytes to differentiate into morphologically and phenotypically mature myeloid cells. The mec
Autor:
Sante Tura, Emanuela Ottaviani, Barbara Gamberi, S. Manfroi, Patrizia Tosi, Giuseppe Visani, A. Cenacchi
Publikováno v:
Leukemia & Lymphoma. 15:143-147
All-trans retinoic acid (ATRA) is currently being used as remission induction treatment for acute promyelocytic leukemia (APL). Conventional chemotherapy is added both during and after ATRA treatment, in order to avoid the occurrence of hyperleukocyt