Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S. M. van Liempd"'
Autor:
S. M. van Liempd, D. Cabrera, F. Y. Lee, E. González, E. C. Dell’Angelica, C. A. Ghiani, J. M. Falcon-Perez
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Biogenesis of lysosome-related organelles complex-1 (BLOC-1) is a protein complex involved in the formation of endosomal tubular structures that mediates the sorting of protein cargoes to specialised compartments. In this study, we present i
Externí odkaz:
https://doaj.org/article/3b75ff7c17f24ce9892424db41d9bd69
Autor:
John H. N. Meerman, R. Ramautar, Tim Schenk, S. M. van Liempd, Jan N. M. Commandeur, H. Irth, Jeroen Kool, J. Beckman, Nico P. E. Vermeulen, F. J. J. De Kanter
Publikováno v:
Journal of Medicinal Chemistry, 49(11), 3287-3292. American Chemical Society
Kool, J, Ramautar, R, van Liempd, S M, Beckman, J, de Kanter, F J J, Meerman, J H N, Schenk, T, Irth, H, Commandeur, J N M & Vermeulen, N P E 2006, ' Rapid
profiling of estrogen receptor binding metabolites of tamoxifen. ', Journal of Medicinal Chemistry, vol. 49, no. 11, pp. 3287-3292 . https://doi.org/10.1021/jm0507936
Kool, J, Ramautar, R, van Liempd, S M, Beckman, J, de Kanter, F J J, Meerman, J H N, Schenk, T, Irth, H, Commandeur, J N M & Vermeulen, N P E 2006, ' Rapid
profiling of estrogen receptor binding metabolites of tamoxifen. ', Journal of Medicinal Chemistry, vol. 49, no. 11, pp. 3287-3292 . https://doi.org/10.1021/jm0507936
Here we present a high-resolution screening (HRS) methodology for postcolumn on-line profiling of metabolites with affinity for the estrogen receptor α (ERα). Tamoxifen, which is metabolized into multiple metabolites, was used as the model compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1f379f0341b11d4d09030a21bff1de
https://research.vu.nl/en/publications/82ce93be-0d84-441e-907d-bffd0187e3f4
https://research.vu.nl/en/publications/82ce93be-0d84-441e-907d-bffd0187e3f4
Autor:
S. M. van Liempd, Wilfried M. A. Niessen, H. Irth, Jeroen Kool, Nico P. E. Vermeulen, D.E. van Elswijk
Publikováno v:
van Liempd, S M, Kool, J, Niessen, W M A, van Elswijk, D A, Irth, H & Vermeulen, N P E 2006, '
formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators ', Drug Metabolism and Disposition, vol. 34, no. 9, pp. 1640-9 . https://doi.org/10.1124/dmd.106.010355
Drug Metabolism and Disposition, 34(9), 1640-9. American Society for Pharmacology and Experimental Therapeutics
formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators ', Drug Metabolism and Disposition, vol. 34, no. 9, pp. 1640-9 . https://doi.org/10.1124/dmd.106.010355
Drug Metabolism and Disposition, 34(9), 1640-9. American Society for Pharmacology and Experimental Therapeutics
We have developed a fully automated bioreactor coupled to an on-line receptor affinity detection system. This analytical system provides detailed information on pharmacologically active metabolites of selective estrogen receptor modulators (SERMs) ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8da0a1a0faae8c0a6d60584ee31e3f7
https://research.vu.nl/en/publications/82eeba78-dca3-4ed2-9035-ed1d9543de2b
https://research.vu.nl/en/publications/82eeba78-dca3-4ed2-9035-ed1d9543de2b