Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S. M. Torkelson"'
Publikováno v:
Journal of medicinal chemistry. 32(5)
A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine showed biphasic activity in competition binding stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610bf5b72c476b144f9786f281a46ec9
https://pubmed.ncbi.nlm.nih.gov/2565402
https://pubmed.ncbi.nlm.nih.gov/2565402
Publikováno v:
Molecular pharmacology. 33(1)
The flexible dopamine (DA) molecule exists in one or the other of its two conformational extremes (alpha- or beta-rotamer) and its receptor in the anterior pituitary gland exists in a high and a low affinity state. A series of novel, rigid DA congene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::344817daa42d0d2435499dcf98e76dd9
https://pubmed.ncbi.nlm.nih.gov/3336350
https://pubmed.ncbi.nlm.nih.gov/3336350
Publikováno v:
ChemInform. 20
A series of 2-substituted octahydrobenzo[f]quinolines has been synthesized and assayed for dopamine agonist activity. Only the compounds corresponding to the beta-rotameric conformation of dopamine showed biphasic activity in competition binding stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c34de88928efd92d83c339e66c71c6ed
https://doi.org/10.1002/chin.198939192
https://doi.org/10.1002/chin.198939192