Zobrazeno 1 - 10
of 121
pro vyhledávání: '"S. M. Shalet"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:2756-2761
Radiotherapy is a central component in the treatment of many brain tumors, but long-term sequelae include GH deficiency and increased risk of secondary neoplasms. It is unclear whether replacement therapy with GH (GHRT) further increases this risk.Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a3afa8225aa453180af942da333954
https://doi.org/10.1210/jc.2011-0112
https://doi.org/10.1210/jc.2011-0112
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:4412-4415
The effect of an acute bolus of GH on serum leptin in normal individuals and the factors affecting this response have not previously been studied. Seventeen healthy volunteers with normal body mass index, with ages ranging from 20.5–78.2 yr were st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892d85341e67f0a086a7f158a20dde15
https://doi.org/10.1210/jcem.86.9.7796
https://doi.org/10.1210/jcem.86.9.7796
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 84:1288-1295
In human studies, the principal determinant of serum leptin concentrations is fat mass (FM), but lean mass (LM) also has a significant negative influence. GH treatment in GH deficiency (GHD) alters body composition, increasing LM and decreasing FM, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85d88f4afeefc6365e1329fa1157564
https://doi.org/10.1210/jcem.84.4.5608
https://doi.org/10.1210/jcem.84.4.5608
Autor:
S M, Shalet
Publikováno v:
International Journal of Clinical Practice. 52:108-111
Growth hormone deficiency in adult life is associated with a number of adverse biological changes which include osteopenia, reduced exercise capacity, altered body composition, deleterious alterations in the lipid profile and insulin status, and redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1646254e76821272088a5b1b4fcbae8a
https://doi.org/10.1111/j.1742-1241.1998.tb11577.x
https://doi.org/10.1111/j.1742-1241.1998.tb11577.x
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:1462-1466
The age-related decline in GH secretion has been implicated in the development of osteoporosis. GH-deficient adults show a significant reduction in bone mineral density (BMD), which is greater in those with childhood-onset GH deficiency than in those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c26c358ae9fd2986eaab6908a19353b4
https://doi.org/10.1210/jcem.82.5.3932
https://doi.org/10.1210/jcem.82.5.3932
Autor:
A L Ogilvy-Stuart, S M Shalet
Publikováno v:
Archives of Disease in Childhood. 73:141-146
The impact of treatment with either cranial or craniospinal irradiation with or without cytotoxic chemotherapy for a brain tumour distant from the hypothalamic-pituitary axis was assessed in 29 children who had reached final height. All had received
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374b1452bc2fa563c9a162809b310e45
https://doi.org/10.1136/adc.73.2.141
https://doi.org/10.1136/adc.73.2.141
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 80:1869-1875
Early pubertal boys (testicular volume, 4-6 mL) with constitutionally delayed growth and puberty were randomized to 3 months of treatment after a baseline 12-h overnight hormone profile: group 1 (n = 5), daily placebo; group 2 (n = 5), 2.5 mg oxandro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a357bcb4de880eb82e68a9e8e79be3
https://doi.org/10.1210/jcem.80.6.7775634
https://doi.org/10.1210/jcem.80.6.7775634
Publikováno v:
Clinical Endocrinology. 41:163-168
Summary OBJECTIVE Cranial irradiation frequently results In growth hormone (GH) deficiency. Patients with radiation-induced GH deficiency usually remain responsive to exogenous growth hormone releasing hormone, implying radiation damages the hypothal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2df82ae939e07b658037107b0f1bc31
https://doi.org/10.1111/j.1365-2265.1994.tb02525.x
https://doi.org/10.1111/j.1365-2265.1994.tb02525.x
Autor:
D. J. OʼHalloran, S. M. Shalet
Publikováno v:
The Endocrinologist. 4:44-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d11bc382f241c133cf6c8759a9229eb
https://doi.org/10.1097/00019616-199401000-00008
https://doi.org/10.1097/00019616-199401000-00008
Autor:
Helen Buckler, S. M. Shalet, J A Cantrill, D.C. Anderson, William R. Robertson, H.O.D. Critchley
Publikováno v:
Clinical Endocrinology. 38:209-217
We evaluated the efficacy of ovulation induction using purified FSH in either low dose or conventional dosage in patients with polycystic ovarian syndrome. We assessed whether gonadotrophin measurement by radioimmunoassay or immunoradiometric assay i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18a5a9d2f060b45680e36146de982f2
https://doi.org/10.1111/j.1365-2265.1993.tb00995.x
https://doi.org/10.1111/j.1365-2265.1993.tb00995.x