Výsledky vyhledávání - "S. M. Galbraith"

Antivascular cancer treatments: imaging biomarkers in pharmaceutical drug development

Autor: S M Galbraith

Publikováno v: The British Journal of Radiology. 76:S83-S86

Over the last several years there have been a large number of drugs brought into the clinic for the treatment of cancer targeting antiangiogenic or antivascular mechanisms. The matrix metalloproteinase inhibitors (MMPIs) are an example of one group o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c2ad1f1af779e8c8a64b529ba09d9e
https://doi.org/10.1259/bjr/15255885

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Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo

Autor: S M, Galbraith, D J, Chaplin, F, Lee, M R, Stratford, R J, Locke, B, Vojnovic, G M, Tozer

Publikováno v: Anticancer research. 21(1A)

Combretastatin A4 Phosphate (CA4P) is a tubulin binding agent which causes rapid tumour vascular shutdown. It has anti-proliferative and apoptotic effects on dividing endothelial cells after prolonged exposure, but these effects occur on a much longe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3bcf702bd992fb458061eb43fea3ceea
https://pubmed.ncbi.nlm.nih.gov/11299795

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A retrospective comparison of endoscopic stenting alone with stenting and radiotherapy in non-resectable cholangiocarcinoma

Autor: M. F. Spittle, S. M. Galbraith, A. R. W. Hatfield, T. E. Bowling, J. Solano

Publikováno v: Gut. 39(6)

BACKGROUND AND AIMS: Radiotherapy has been reported to be of benefit in prolonging the survival of patients with cholangiocarcinoma. This study examined whether radiotherapy in addition to endoscopic stenting improved survival. SUBJECTS: 56 patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5d15775d47418acdce3093066338e5
https://pubmed.ncbi.nlm.nih.gov/9038668

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Effect of IGF-1R inhibitor BMS-754807 on tumor glucose metabolism and proliferation in Sal-IGF xenografts by FDG and FLT- PET imaging

Autor: Frank Lee, Ching-Ping Ho, Ricardo M. Attar, F. Graf Finckenstein, B. S. Krishnan, S. M. Galbraith, Marco M. Gottardis, Joan M. Carboni, P. L. Chow, David Kan

Publikováno v: Journal of Clinical Oncology. 27:e14501-e14501

e14501 Background: The type 1 insulin-like growth factor receptor (IGF-1R) plays a critical role in mitogenesis and survival in a variety of human tumor cells. IGF-1R is also closely related to the insulin receptor (IR). It is becoming increasingly e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::281cfddb0bff41695eb8b7dea467f876
https://doi.org/10.1200/jco.2009.27.15_suppl.e14501

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