Zobrazeno 1 - 10
of 29
pro vyhledávání: '"S. M. Freund"'
Publikováno v:
Journal of biomolecular NMR. 18(3)
Publikováno v:
Journal of molecular biology. 296(5)
The detailed characterization of denatured proteins remains elusive due to their mobility and conformational heterogeneity. NMR studies are beginning to provide clues regarding residual structure in the denatured state but the resulting data are too
Publikováno v:
Journal of molecular biology. 292(1)
A detailed structural analysis of interactions between denatured proteins and GroEL is essential for an understanding of its mechanism. Minichaperones constitute an excellent paradigm for obtaining high-resolution structural information about the bin
Autor:
A E, Meekhof, S M, Freund
Publikováno v:
Journal of biomolecular NMR. 14(1)
In proteins, dynamic mobility is an important feature of structure, stability, and biomolecular recognition. Uniquely sensitive to motion throughout the milli- to picosecond range, rates of transverse relaxation, R2, are commonly obtained for the cha
Autor:
A E, Meekhof, S M, Freund
Publikováno v:
Journal of molecular biology. 286(2)
The energy landscape for the denatured state of a protein provides a key to understanding early folding events. We have attempted to map this landscape for the third fibronectin type III domain from human tenascin (TNfn3), a compact 9.5 kDa beta-sand
Publikováno v:
Journal of molecular biology. 278(2)
The structural and dynamic properties of an immunoglobulin superfamily domain (IgSF), Ig 18', have been characterised by NMR at 285 K, in the presence of 4.2 M and 6.0 M urea, respectively. Analysis of chemical shift deviations, 3JHNHalpha coupling c
Publikováno v:
Journal of molecular biology. 268(2)
Barstar an 89-residue protein consisting of four helices and a three-stranded parallel beta-sheet, is the intracellular inhibitor of the endoribonuclease barnase. Barstar C40/82A, a mutant in which the two cysteine residues have been replaced by alan
Publikováno v:
Biochemistry. 33(30)
We present the high-resolution solution structure and 13C assignments of wild-type barstar, an 89 amino acid residue polypeptide inhibitor of barnase, derived from heteronuclear NMR techniques. These were obtained from measurements on unlabeled, unif
Publikováno v:
The Journal of Chemical Physics. 67:4545-4556
The isotopically selective dissociation of SF6 induced by intense CO2 laser radiation has been experimentally investigated. These experiments demonstrate that the reaction yield can be greatly enhanced by designing the reaction cells for better photo
Autor:
S. M. Freund, J. C. Stephenson
Publikováno v:
The Journal of Chemical Physics. 65:1893-1900
Vibrationally excited nitric oxide, produced by absorption of carbon monoxide laser radiation, was found to react significantly faster at T=298 °K than does thermal NO in the reaction with ozone: NO+O3→k1NO2* (2B1)+O2, (1) NO(v=1)+O3→k′1NO*2(2