Zobrazeno 1 - 10
of 22
pro vyhledávání: '"S. M. Channon"'
Publikováno v:
Journal of the American Society of Nephrology. 8:632-637
Correction of acidosis in hemodialysis (HD) decreases protein degradation. The effect of the correction of chronic metabolic acidosis in chronic renal failure patients treated with HD was determined from the kinetics of infused L-[1-(13)C]leucine. Si
Autor:
C. Hetherington, D. Reaich, T. H. J. Goodship, K. A. Graham, C. M. Scrimgeour, S. M. Channon, Robert W. Wilkinson
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 268:E121-E126
To test the hypothesis that acidosis contributes to the insulin resistance of chronic renal failure (CRF) and impairs the action of insulin to decrease protein degradation, eight CRF patients were studied using the combined L-[1–13C]leucine-euglyce
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 265:E230-E235
The effect of correction of acidosis in chronic renal failure (CRF) was determined from the kinetics of infused L-[1-13C]leucine. Nine CRF patients were studied before (acid) and after two 4-wk treatment periods of sodium bicarbonate (NaHCO3) and sod
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 263:E735-E739
The effect of acidosis on whole body protein turnover was determined from the kinetics of infused L-[1-13C]leucine. Seven healthy subjects were studied before (basal) and after (acid) the induction of acidosis with 5 days oral ammonium chloride (basa
Publikováno v:
European journal of clinical investigation. 20(4)
To examine the possible effects of hyperoxalaemia on anaerobic metabolism and erythrocyte pyruvate kinase activity, we induced a rise in plasma oxalate in 11 dialysis patients by the oral administration of ascorbic acid, 500 mg day-1 for 3 weeks. Blo
Publikováno v:
Nephron. 54:276-276
Oxalate has been reported to have a toxic effect on endothelial cells in culture [2], leading to suggestions that hyperoxalaemia may contribute to endothelial damage and thus to arterial disease in patients receiving dialysis. We studied this possibi
Autor:
S. M. Channon, I. S. Parkinson, M. K. Ward, L.R. Adonai, Charles R.V. Tomson, Michael F. Laker
Publikováno v:
Clinica Chimica Acta. 179:97-108
An inexpensive, continuous flow assay for the determination of oxalate in plasma is described. The assay is based on the bioluminescent determination of NADH, a product of the degradation of oxalate by oxalate decarboxylase and formate dehydrogenase,
Effect of pyridoxine supplementation on plasma oxalate concentrations in patients receiving dialysis
Publikováno v:
European Journal of Clinical Investigation. 19:201-205
Plasma oxalate and erythrocyte glutamic oxaloacetate transaminase activity (EGOT) (an indicator of nutritional status with respect to pyridoxine) were measured in 21 patients maintained on regular continuous ambulatory peritoneal dialysis or haemodia
Publikováno v:
Clinical Chemistry. 31:1969-1973
We describe methods for studying the binding of Al by protein in serum: ultrafiltration, gel filtration, and immuno-affinity chromatography. For ultrafiltration we used an Amicon YM10 cellophane membrane with a nominal cutoff of 10 000 Da to separate
Publikováno v:
Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress. 21
We have measured serum nickel concentrations using flameless atomic absorption spectrophotometry. In 71 normals the median concentration was 1.0 micrograms/L, range less than 0.6-3.0 micrograms/L. Increased concentrations (p less than 0.05) were foun