Active immunization against murine TNFα peptides in mice: generation of endogenous antibodies cross-reacting with the native cytokine and in vivo protection

Autor: E. G. Muel, C. J. Capini, Jacques Chomilier, P. M. Haumont, Ludovic Autin, Jean-Paul Briand, M. A. Laborie, S. Paturance, S. Muller, Amu Therwath, Jean-François Zagury, S. M. Bertin-Maghit, Marie-Christophe Boissier, Natacha Bessis, J. M. Cavaillon, E. M. Bernier

Publikováno v: Vaccine
Vaccine, Elsevier, 2004, 22, pp.3144-3153. ⟨10.1016/j.vaccine.2004.01.064⟩
Vaccine, 2004, 22, pp.3144-3153. ⟨10.1016/j.vaccine.2004.01.064⟩
Vaccine, Elsevier, 2004, 22, pp.3144-3153. 〈10.1016/j.vaccine.2004.01.064〉

New lines of treatment targeting cytokines have been successfully developed recently and are now widely used in therapy. They are based on passive administration of cytokine inhibitors either soluble receptors or mAbs and the major example is TNFalph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbb6bf397fdf4a9f7a9fc96cb6db759
https://hal.archives-ouvertes.fr/hal-00087143