Zobrazeno 1 - 10
of 1 899
pro vyhledávání: '"S. Louis"'
Autor:
Ruchi Yadav, Quan-Zhen Li, Hanwen Huang, S. Louis Bridges, J. Michelle Kahlenberg, Arlene A. Stecenko, Balázs Rada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionWhile cystic fibrosis (CF) lung disease is characterized by persistent inflammation and infections and chronic inflammatory diseases are often accompanied by autoimmunity, autoimmune reactivity in CF has not been studied in depth.MethodsI
Externí odkaz:
https://doaj.org/article/0786abdff9e54abbba1b6e68cd82499e
Autor:
Shelby C. Osburn, Matthew A. Romero, Paul A. Roberson, Petey W. Mumford, Derek A. Wiggins, Jeremy S. McAdam, Devin J. Drummer, S. Louis Bridges, Marcas M. Bamman, Michael D. Roberts
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-7 (2022)
Abstract Objective Long INterspersed Element-1 (L1) is an autonomous transposable element in the genome. L1 transcripts that are not reverse transcribed back into the genome can accumulate in the cytoplasm and activate an inflammatory response via th
Externí odkaz:
https://doaj.org/article/a5ad1d87459144dba239908edd3bd6a1
Publikováno v:
AIP Advances, Vol 13, Iss 1, Pp 015206-015206-18 (2023)
Spiking artificial neurons emulate the voltage spikes of biological neurons and constitute the building blocks of a new class of energy efficient, neuromorphic computing systems. Antiferromagnetic materials can, in theory, be used to construct spikin
Externí odkaz:
https://doaj.org/article/6ad07e3dc0e943b9bc03a08b6bb32beb
Autor:
William Rigby, Jane H. Buckner, S. Louis Bridges, Marleen Nys, Sheng Gao, Martin Polinsky, Neelanjana Ray, Vivian Bykerk
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-13 (2021)
Abstract Background Certain risk alleles associated with autoantibody-positive rheumatoid arthritis (RA) have been linked to poorer prognoses. In patients with autoantibody-positive RA, abatacept shows differential efficacy to tumor necrosis factor i
Externí odkaz:
https://doaj.org/article/8c6434296d9e4f0b8dca1de3b60413e1
Autor:
Vishal Sharma, Brandon J. Pope, Nathan V. Santiago, Molly T. Boland, Dongmei Sun, Richard J. Reynolds, Alexander J. Szalai, S. Louis Bridges Jr, Chander Raman
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 4, Pp 277-283 (2021)
Objective We investigated whether a previously reported association of IFNGR expression with rheumatoid arthritis (RA) and its radiographic severity reflects differences in proximal interferon‐γ (IFN‐γ) signaling in T cells from patients with R
Externí odkaz:
https://doaj.org/article/d888a192d9584d7eb732e45106c2557b
Autor:
Ruchi Yadav, Rachel W. Linnemann, Joanne Michelle Kahlenberg, S. Louis Bridges, Arlene A. Stecenko, Balázs Rada
Publikováno v:
Autoimmunity, Vol 53, Iss 8, Pp 476-484 (2020)
Although extracellular host DNA (ecDNA) levels in CF airways were linked to airflow obstruction and recombinant DNAse therapy is beneficial for CF patients, it remains incompletely understood whether ecDNA also leads to an autoimmune response. Here w
Externí odkaz:
https://doaj.org/article/32ae24f283ad49e296a84384ba2168ff
Autor:
Lisandro D. Colantonio, Kenneth G. Saag, Jasvinder A. Singh, Ligong Chen, Richard J. Reynolds, Angelo Gaffo, Timothy B. Plante, Jeffrey R. Curtis, S. Louis Bridges, Emily B. Levitan, Ninad S. Chaudhary, George Howard, Monika M. Safford, Paul Muntner, Marguerite Ryan Irvin
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Background Gout has been associated with a higher risk for coronary heart disease (CHD) and stroke in some prior studies. Few studies have assessed the association of gout with incident heart failure (HF). Methods We analyzed data from 5713
Externí odkaz:
https://doaj.org/article/4fe36d5dbfe846f29b05112874af6444
Publikováno v:
ACR Open Rheumatology, Vol 1, Iss 9, Pp 571-579 (2019)
Human leukocyte antigen c (HLA‐C) is a polymorphic membrane protein encoded by the HLA‐C gene in the class I major histocompatibility complex. HLA‐C plays an essential role in protection against cancer and viruses but has also been implicated i
Externí odkaz:
https://doaj.org/article/ef9d845f65eb4dec8ecfcee98e6fb8ad
Publikováno v:
BMC Bioinformatics, Vol 18, Iss S14, Pp 17-30 (2017)
Abstract Background Much effort has been devoted to the discovery of specific mechanisms between drugs and single targets to date. However, as biological systems maintain homeostasis at the level of functional networks robustly controlling the intern
Externí odkaz:
https://doaj.org/article/f095c01c2a7c4d38a878704548941e89
Autor:
Maria I. Danila, Vincent A. Laufer, Richard J. Reynolds, Qi Yan, Nianjun Liu, Peter K. Gregersen, Annette Lee, Marlena Kern, Carl D. Langefeld, Donna K. Arnett, S. Louis Bridges
Publikováno v:
Molecular Medicine, Vol 23, Iss 1, Pp 177-187 (2017)
Abstract More than 100 risk loci for rheumatoid arthritis (RA) have been identified in individuals of European and Asian descent, but the genetic basis for RA in African Americans is less well understood. We genotyped 610 African Americans with autoa
Externí odkaz:
https://doaj.org/article/1da6c8662a87414baa17dedcf588818b