Zobrazeno 1 - 10
of 1 122
pro vyhledávání: '"S. Looareesuwan"'
Autor:
Jean-René Kiechel, Walter R. J. Taylor, S. Looareesuwan, Wattana Leowattana, V. Navaratnam, P. Wilairatama, Srivicha Krudsood, Noppadon Tangpukdee, K Chalermrut, Piero Olliaro, Surash Ramanathan, Michel Vaillant
Publikováno v:
Tropical Medicine & International Health. 16:458-465
Summary Objective To ascertain whether mefloquine (MQ) produces electrocardiogram (ECG) changes that could be a risk for Torsades de Pointe (TdP), a potentially malignant, ventricular tachyarrhythmia. Methods We measured the Fridericia corrected QT (
Autor:
Jean-René Kiechel, Walter R. J. Taylor, Polrat Wilairatana, Wattana Leowattana, K. Chalermrut, Weerapong Phumratanaprapin, V. Navaratnam, Srivicha Krudsood, Noppadon Tangpukdee, Piero Olliaro, Michel Vaillant, S. Looareesuwan, Surash Ramanathan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:3730-3737
A new fixed-dose artesunate (AS)-mefloquine (MQ) was assessed in adults hospitalized for 28 days with uncomplicated drug-resistant falciparum malaria. The patients ( n = 25/arm) were treated with (i) two fixed-dose tablets (AS-MQ arm; 100 mg AS-200 m
Autor:
Pornlada Nuchnoi, Hathairad Hananantachai, S. Looareesuwan, Izumi Naka, Jun Ohashi, Katsushi Tokunaga, Srivicha Krudsood, Ryosuke Kimura, Jintana Patarapotikul
Publikováno v:
Annals of Human Genetics. 72:327-336
Although cerebral malaria is a major life-threatening complication of Plasmodium falciparum infection, its pathophysiology is not well understood. Prolonged activation of the T helper type 1 (Th1) response characterized by the production of pro-infla
Autor:
S. Looareesuwan, James Allen, Patrick Yeramian, Udomsak Silachamroon, Jesse J. Kwiek, Noppadon Tangpukdee, K Chalermrut, Srivicha Krudsood, Richard R. Tidwell, Steven R. Meshnick, Reto Brun
Publikováno v:
The Journal of Infectious Diseases. 192:319-322
Background. DB289 is the orally active prodrug of the diamidine DB75, which was developed for the treatment of human African trypanosomiasis. Methods. We tested the safety and efficacy of DB289 for the treatment of Plasmodium vivax and acute, uncompl
Autor:
S. Looareesuwan, Weerapong Phumratanaprapin, Polrat Wilairatana, Valai Bussaratid, Srivicha Krudsood, Pratap Singhasivanon, S Srivilirit, Sombat Treeprasertsuk, Udomsak Silachamroon
Publikováno v:
Scopus-Elsevier
To define the current efficacy of Fansidar (F. Hoffmann-La Roche Ltd., Basel Switzerland) (pyrimethamine and sulfadoxine), primaquine in a high dose, and artesunate for treating acute Plasmodium vivax malaria, we conducted a comparative clinical tria
Publikováno v:
Annals of Tropical Medicine & Parasitology. 93:449-455
Autor:
Michèle van Vugt, S. Looareesuwan, Alan Brockman, N J White, Christine Luxemburger, L Phaipun, Insa Gathmann, Polrat Wilairatana, B Gemperli, François Nosten
Publikováno v:
Scopus-Elsevier
The new oral fixed combination artemether-lumefantrine (CGP 56697) has proved to be an effective and well-tolerated treatment of multi-drug resistant Plasmodium falciparum malaria, although cure rates using the four-dose regimen have been lower than
Autor:
L. H. Camacho, V. R. Gordeuk, P. Wilairatana, P. Pootrakul, G. M. Brittenham, S. Looareesuwan
Publikováno v:
Annals of Tropical Medicine & Parasitology. 92:525-537
Autor:
Karl H. Rieckmann, Vanijanonta S, Polrat Wilairatana, Dennis E. Kyle, Michael D. Edstein, S. Looareesuwan
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 56:498-502
The objective of this study was to examine the disposition of proguanil in malaria-infected Thai patients with acute uncomplicated falciparum malaria. Eleven patients were administered 500 mg of proguanil twice a day for three days (total dose = 3,00
Publikováno v:
Journal of travel medicine. 6
Safe and effective new drugs are needed for treatment of malaria. Atovaquone and proguanil hydrochloride is a new antimalarial combination that has recently become available in many countries.Data from clinical trials evaluating atovaquone/proguanil