Zobrazeno 1 - 10
of 116
pro vyhledávání: '"S. Le Hellard"'
Autor:
S. Le Hellard
Publikováno v:
European Psychiatry, Vol 64, Pp S34-S34 (2021)
Abstract Body Major mental disorders have typically a complex aetiology where both genetic and environmental risk factors have been implicated. It has also been suggested that these risk factors could be interactive rather than just additional. In th
Externí odkaz:
https://doaj.org/article/e42f66067bf2485ea8a7d7580e3051ee
Publikováno v:
European Psychiatry, Vol 64, Pp S70-S71 (2021)
Abstract Body Genome-wide Association Studies in Psychiatry - Current Perspectives Last decade was exciting time for human genetic studies. Genome-wide association studies (GWASs), used to examine the association of genotyped variants across the enti
Externí odkaz:
https://doaj.org/article/e825cb477ce1475fbb45dec27191ebe8
Autor:
Stephan Zipfel, Hidetoshi Inoko, K. Fischer, Laramie E. Duncan, Jochen Seitz, Lars Klareskog, Ina Giegling, Grant W. Montgomery, Manuel Föcker, Colin A. Johnson, Agnieszka Słopień, Dong Li, M. C. T. Slof-Op 't Landt, Thomas Werge, Janiece E. DeSocio, Stefan Ehrlich, Joseph M. Boden, Patrick F. Sullivan, M. La Via, Bochao Danae Lin, Andreas Karwautz, Ilka Boehm, Lenka Foretová, Stephen W. Scherer, Anders Juréus, Jolanta Lissowska, Janne Tidselbak Larsen, Antonio Julià, A. Metspalu, Roger A.H. Adan, George Dedoussis, Stefan Herms, Franziska Ritschel, Martin A. Kennedy, Vesna Boraska Perica, S.D. Gordon, Johanna Giuranna, Janet Treasure, Youl-Ri Kim, Joanna Hauser, Manfred M. Fichter, P.E. Slagboom, Wade H. Berrettini, Kirstin L. Purves, Fernando Fernández-Aranda, Eleftheria Zeggini, Nadia Micali, Anne Farmer, Beata Swiatkowska, Tracey D. Wade, Claudette Boni, Fragiskos Gonidakis, Ioanna Ntalla, Johannes Pantel, Raquel Rabionet, Pierre J. Magistretti, Johannes Hebebrand, Mario Maj, Sietske G. Helder, Roland Burghardt, Sarah E. Medland, Maurizio Clementi, John F. Pearson, Gerd Wagner, V. Janout, Susana Jiménez-Murcia, Mikael Landén, Samuli Ripatti, Sandro Sorbi, Martien J H Kas, Leonid Padyukov, Zeynep Yilmaz, Kelly L. Klump, Paul Lichtenstein, Shuyang Yao, Dan Rujescu, James J. Crowley, Valdo Ricca, Palmiero Monteleone, Steve Crawford, Sébastien Guillaume, Liselotte Petersen, Yiran Guo, Stephan Ripke, Beate Herpertz-Dahlmann, Marie Navratilova, S. Gallinger, Anjali K. Henders, Cynthia M. Bulik, Wolfgang Herzog, Alfonso Tortorella, Christian Dina, Garret D. Stuber, A. A. van Elburg, Manuel Mattheisen, Harry Brandt, Hunna J. Watson, Alessandro Rotondo, Roel A. Ophoff, Artemis Tsitsika, Nicholas G. Martin, Sara Marsal, Konstantinos Tziouvas, Ken B. Hanscombe, Alessio Maria Monteleone, Ted Reichborn-Kjennerud, Anu Raevuori, Lars Alfredsson, E. F. van Furth, Hartmut Imgart, Esther Walton, Julie K. O'Toole, Katharina Buehren, Unna N. Danner, Hana Papezova, Katherine M. Kirk, Deborah Kaminská, Lisa R. Lilenfeld, Aarno Palotie, Paola Giusti-Rodríguez, Jennifer Jordan, Gun Peggy Knudsen, L. Slachtova, Ole A. Andreassen, Monica Gratacos Mayora, Elisabeth Widen, Benedetta Nacmias, Nicholas J. Schork, Monika Dmitrzak-Weglarz, Jurjen J. Luykx, André Scherag, Christopher Hübel, Laura M. Thornton, Marion Roberts, Angela Favaro, Catherine M. Olsen, Jaakko Kaprio, S Le Hellard, Federica Tozzi, Monica Forzan, Claes Norring, Leila Karhunen, Karin Egberts, Dalila Pinto, Geòrgia Escaramís, Nicolas Ramoz, Robert D. Levitan, Laura M. Huckins, Ulrike Schmidt, Gerome Breen, Kirsty Kiezebrink, Andreas J. Forstner, Scott J. Crow, Ingrid Meulenbelt, Dimitris Dikeos, Sven Cichon, Daniela Degortes, L. J. Horwood, Tetsuya Ando, Jonathan R. I. Coleman, Stephanie Zerwas, Katherine A. Halmi, Helena Gaspar, Andrew W. Bergen, Elena Tenconi, Katrin Männik, Christopher S. Franklin, Anna Keski-Rahkonen, Sara McDevitt, Marta Tyszkiewicz-Nwafor, Jakob Grove, Philip Gorwood, Christian R. Marshall, Preben Bo Mortensen, Melissa A. Munn-Chernoff, Hakon Hakonarson, Roger D. Cone, Allan S. Kaplan, Paolo Santonastaso, James I. Hudson, M. de Zwaan, Xavier Estivill, James E. Mitchell, Danielle M. Dick, Jessica H. Baker, Peter McGuffin, Walter H. Kaye, Michael Strober, D. B. Woodside, Oliver S. P. Davis, Karen S. Mitchell, David C. Whiteman, Julien Bryois, Nancy L. Pedersen, Philippe Courtet, Virpi M. Leppä, Konstantinos Hatzikotoulas, T Esko, Matteo Cassina, Andreas Birgegård, Anke Hinney, Richard Parker, James L. Kennedy, Elisa Docampo, Ioanna Tachmazidou, Jin P. Szatkiewicz, Alexandra Schosser, Filip Rybakowski, Morten Mattingsdal, Gursharan Kalsi
Publikováno v:
Yearbook of Paediatric Endocrinology.
Autor:
Ole A. Andreassen, Srdjan Djurovic, S. Le Hellard, Francesco Bettella, Martin Tesli, Ingrid Melle, Ingrid Agartz, Petter Andreas Ringen, Trine Vik Lagerberg, Thomas Bjella, Olav B. Smeland, Monica Aas
Publikováno v:
Psychological Medicine. 48:43-49
BackgroundSchizophrenia (SZ) and bipolar disorder (BD) are heritable, polygenic disorders with shared clinical and genetic components, suggesting a psychosis continuum. Cannabis use is a well-documented environmental risk factor in psychotic disorder
Autor:
Bjørn Bjorvatn, Nils Magerøy, Vidar M. Steen, Eirunn Thun, S. Le Hellard, Bente E. Moen, Hans-Richard Brattbakk, Sudheer Giddaluru, Ståle Pallesen, Teresa M. Osland
Publikováno v:
Sleep and Biological Rhythms. 14:55-62
Shift workers often experience circadian misalignment and problems adjusting adequately to their work schedules, which is manifested in the high prevalence rates of shift work disorder, insomnia and sleepiness in this group of workers compared to day
Autor:
Anna C. Need, Katri Räikkönen, Edythe D. London, Jari Lahti, Aiden Corvin, Antony Payton, Russell A. Poldrack, Nikolaos Smyrnis, Matthew C. Keller, Ian J. Deary, Aarno Palotie, Deborah K. Attix, Srdjan Djurovic, Elisabeth Widen, John M. Starr, Fred W. Sabb, Kjetil Sundet, Stella G. Giakoumaki, David C. Liewald, Daniel R. Weinberger, Neil Pendleton, Panos Bitsios, Jin Yu, Ole A. Andreassen, Bettina Konte, Alex Hatzimanolis, William E R Ollier, Johan G. Eriksson, Ina Giegling, Emma Knowles, Dwight Dickinson, Elizabeth T. Cirulli, David C. Glahn, Nelson A. Freimer, Panos Roussos, Aristotle N. Voineskos, Thomas Espeseth, Joey W. Trampush, Dan E. Arking, Gary Davies, Nicholas C. Stefanis, Dan Rujescu, Derek W. Morris, Gary Donohoe, Vidar M. Steen, S. Le Hellard, Anil K. Malhotra, Astri J. Lundervold, Todd Lencz, Ornit Chiba-Falek, Andrea Christoforou, Matthew A. Scult, Emily Drabant Conley, Michael A Horan, Ingrid Melle, M. Gill, Robert M. Bilder, Katherine E. Burdick, Ivar Reinvang, M. L. Z. Yang, Eliza Congdon, Tyrone D. Cannon, Richard E. Straub, Pamela DeRosse, Ahmad R. Hariri, Dimitrios Avramopoulos
Publikováno v:
Molecular Psychiatry
Trampush, J W, Zhan Yang, M L, Knowles, E, Davies, G, Liewald, D, Starr, J, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, Derosse, P, Lundervold, A J, Steen, V M, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, J G, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, K E, Payton, A, Ollier, W, Horan, M, Chiba-Falek, O, Attix, D K, Need, A C, Cirulli, E T, Voineskos, A N, Stefanis, N C, Avramopoulos, D, Hatzimanolis, A, Arking, D E, Smyrnis, N, Bilder, R M, Freimer, N B, Cannon, T D, London, E, Poldrack, R A, Sabb, F W, Congdon, E, Conley, E D, Scult, M, Dickinson, D, Straub, R E, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, A R, Weinberger, D R, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, S, Keller, M C, Andreassen, O A, Deary, I, Glahn, D C, Malhotra, A K & Lencz, T 2017, ' GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function : A report from the COGENT consortium ', Molecular Psychiatry, vol. 22, pp. 336-345 . https://doi.org/10.1038/mp.2016.244
Molecular psychiatry, vol 22, iss 3
Trampush, J W, Yang, M L Z, Yu, J, Knowles, E, Davies, G, Liewald, D C, Starr, J M, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, DeRosse, P, Lundervold, A J, Steen, V M, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, J G, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, K E, Payton, A, Ollier, W, Horan, M, Chiba-Falek, O, Attix, D K, Need, A C, Cirulli, E T, Voineskos, A N, Stefanis, N C, Avramopoulos, D, Hatzimanolis, A, Arking, D E, Smyrnis, N, Bilder, R M, Freimer, N A, Cannon, T D, London, E D, Poldrack, R A, Sabb, F W, Congdon, E, Conley, E D, Scult, M A, Dickinson, D, Straub, R E, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, A R, Weinberger, D R, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, S, Keller, M C, Andreassen, O A, Deary, I J, Glahn, D C, Malhotra, A K & Lencz, T 2017, ' GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function : a report from the COGENT consortium ', Molecular psychiatry, vol. 22, no. 3, pp. 336-345 . https://doi.org/10.1038/mp.2016.244, https://doi.org/10.1038/mp.2016.244
Molecular psychiatry, vol 22, iss 11
Trampush, J W, Zhan Yang, M L, Knowles, E, Davies, G, Liewald, D, Starr, J, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, Derosse, P, Lundervold, A J, Steen, V M, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, J G, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, K E, Payton, A, Ollier, W, Horan, M, Chiba-Falek, O, Attix, D K, Need, A C, Cirulli, E T, Voineskos, A N, Stefanis, N C, Avramopoulos, D, Hatzimanolis, A, Arking, D E, Smyrnis, N, Bilder, R M, Freimer, N B, Cannon, T D, London, E, Poldrack, R A, Sabb, F W, Congdon, E, Conley, E D, Scult, M, Dickinson, D, Straub, R E, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, A R, Weinberger, D R, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, S, Keller, M C, Andreassen, O A, Deary, I, Glahn, D C, Malhotra, A K & Lencz, T 2017, ' GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function : A report from the COGENT consortium ', Molecular Psychiatry, vol. 22, pp. 336-345 . https://doi.org/10.1038/mp.2016.244
Molecular psychiatry, vol 22, iss 3
Trampush, J W, Yang, M L Z, Yu, J, Knowles, E, Davies, G, Liewald, D C, Starr, J M, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, DeRosse, P, Lundervold, A J, Steen, V M, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, J G, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, K E, Payton, A, Ollier, W, Horan, M, Chiba-Falek, O, Attix, D K, Need, A C, Cirulli, E T, Voineskos, A N, Stefanis, N C, Avramopoulos, D, Hatzimanolis, A, Arking, D E, Smyrnis, N, Bilder, R M, Freimer, N A, Cannon, T D, London, E D, Poldrack, R A, Sabb, F W, Congdon, E, Conley, E D, Scult, M A, Dickinson, D, Straub, R E, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, A R, Weinberger, D R, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, S, Keller, M C, Andreassen, O A, Deary, I J, Glahn, D C, Malhotra, A K & Lencz, T 2017, ' GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function : a report from the COGENT consortium ', Molecular psychiatry, vol. 22, no. 3, pp. 336-345 . https://doi.org/10.1038/mp.2016.244, https://doi.org/10.1038/mp.2016.244
Molecular psychiatry, vol 22, iss 11
The complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide association study (GWAS) methods. In an attempt to overcome these barriers, the current study utili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec26100056b46b727e48a65987866d2
https://hdl.handle.net/1956/19271
https://hdl.handle.net/1956/19271
Autor:
Albert Tenesa, Michael A. Horan, Astri J. Lundervold, Ian J. Deary, Sudheer Giddaluru, Stefan Herms, Manuel Mattheisen, Srdjan Djurovic, Vidar M. Steen, John M. Starr, Ivar Reinvang, Thomas Espeseth, D. C. Liewald, Andrea Christoforou, Carla P. D. Fernandes, Antony Payton, Neil Pendleton, Sarah E. Harris, William Ollier, Per Hoffman, S. Le Hellard, Sven Cichon, Gary Davies, Paul Haggarty
Publikováno v:
Genes, Brain and Behavior
Genes, Brain, and Behavior
Genes, brain and behavior 13(7), 663–674 (2014). doi:10.1111/gbb.12152
Christoforou, A, Espeseth, T, Davies, G, Fernandes, C P D, Giddaluru, S, Mattheisen, M, Tenesa, A, Harris, S E, Liewald, D C, Payton, A, Ollier, W, Horan, M, Pendleton, N, Haggarty, P, Djurovic, S, Herms, S, Hoffman, P, Cichon, S, Starr, J M, Lundervold, A, Reinvang, I, Steen, V M, Deary, I J & Le Hellard, S 2014, ' GWAS-based pathway analysis differentiates between fluid and crystallized intelligence ', Genes, Brain and Behavior, vol. 13, no. 7, pp. 663-674 . https://doi.org/10.1111/gbb.12152
Christoforou, A, Espeseth, T, Davies, G, Fernandes, C P D, Giddaluru, S, Mattheisen, M, Tenesa, A, Harris, S E, Liewald, D C, Payton, A, Ollier, W, Horan, M, Pendleton, N, Haggarty, P, Djurovic, S, Herms, S, Hoffman, P, Cichon, S, Starr, J M, Lundervold, A, Reinvang, I, Steen, V M, Deary, I J & Le Hellard, S 2014, ' GWAS-based pathway analysis differentiates between fluid and crystallized intelligence ' Genes, Brain and Behavior . https://doi.org/10.1111/gbb.12152
Genes, Brain, and Behavior
Genes, brain and behavior 13(7), 663–674 (2014). doi:10.1111/gbb.12152
Christoforou, A, Espeseth, T, Davies, G, Fernandes, C P D, Giddaluru, S, Mattheisen, M, Tenesa, A, Harris, S E, Liewald, D C, Payton, A, Ollier, W, Horan, M, Pendleton, N, Haggarty, P, Djurovic, S, Herms, S, Hoffman, P, Cichon, S, Starr, J M, Lundervold, A, Reinvang, I, Steen, V M, Deary, I J & Le Hellard, S 2014, ' GWAS-based pathway analysis differentiates between fluid and crystallized intelligence ', Genes, Brain and Behavior, vol. 13, no. 7, pp. 663-674 . https://doi.org/10.1111/gbb.12152
Christoforou, A, Espeseth, T, Davies, G, Fernandes, C P D, Giddaluru, S, Mattheisen, M, Tenesa, A, Harris, S E, Liewald, D C, Payton, A, Ollier, W, Horan, M, Pendleton, N, Haggarty, P, Djurovic, S, Herms, S, Hoffman, P, Cichon, S, Starr, J M, Lundervold, A, Reinvang, I, Steen, V M, Deary, I J & Le Hellard, S 2014, ' GWAS-based pathway analysis differentiates between fluid and crystallized intelligence ' Genes, Brain and Behavior . https://doi.org/10.1111/gbb.12152
Cognitive abilities vary among people. About 40–50% of this variability is due to general intelligence (g), which reflects the positive correlation among individuals' scores on diverse cognitive ability tests. g is positively correlated with many l
Autor:
I. Melle, D. Morris, John M. Starr, A. Palotie, Richard E. Straub, P. Bitsios, Ornit Chiba-Falek, Kjetil Sundet, Daniel R. Weinberger, Neil Pendleton, Edythe D. London, Nikolaos Smyrnis, Jari Lahti, Emma Knowles, E. Widen, Arvid Lundervold, Katri Räikkönen, Elizabeth T. Cirulli, G. Donohoe, Eliza Congdon, Gary Davies, Deborah K. Attix, Aristotle Voineskos, S Le Hellard, Dwight Dickinson, Joey W. Trampush, Michael A. Horan, Bettina Konte, Stella G. Giakoumaki, Ming Yang, Emily Drabant Conley, N Freimer, Alex Hatzimanolis, Ole A. Andreassen, Matthew C. Keller, Robert M. Bilder, Katherine E. Burdick, M. Gill, W. E. R. Ollier, Tyrone D. Cannon, David C. Glahn, Dan Rujescu, P. DeRosse, Anil K. Malhotra, Vidar M. Steen, Fred W. Sabb, A Payton, Todd Lencz, Ahmad R. Hariri, Panos Roussos, Dimitrios Avramopoulos, D.E. Arking, Andrea Christoforou, Matthew A. Scult, Jin Yu, Johan G. Eriksson, A. Corvin, D C Liewald, Ina Giegling, Ian J. Deary, Srdjan Djurovic, Thomas Espeseth, A. C. Need, Russell A. Poldrack, N.C. Stefanis, Ivar Reinvang
Publikováno v:
Trampush, J W, Yang, M L Z, Yu, J, Knowles, E, Davies, G, Liewald, D C, Starr, J M, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, DeRosse, P, Lundervold, A J, Steen, V M, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, J G, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, K E, Payton, A, Ollier, W, Horan, M, Chiba-Falek, O, Attix, D K, Need, A C, Cirulli, E T, Voineskos, A N, Stefanis, N C, Avramopoulos, D, Hatzimanolis, A, Arking, D E, Smyrnis, N, Bilder, R M, Freimer, N A, Cannon, T D, London, E, Poldrack, R A, Sabb, F W, Congdon, E, Conley, E D, Scult, M A, Dickinson, D, Straub, R E, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, A R, Weinberger, D R, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Le Hellard, S, Keller, M C, Andreassen, O A, Deary, I J, Glahn, D C, Malhotra, A K & Lencz, T 2017, ' Erratum: GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function : a report from the COGENT consortium ', Molecular psychiatry, vol. 22, no. 11, pp. 1651-1652 . https://doi.org/10.1038/mp.2017.197
Correction to: Molecular Psychiatry (2017) 22, 336–345; doi:10.1038/mp.2016.244;published online 17 January 2017 Data access for several cohorts used in this study was provided by the National Center for Biotechnology Information (NCBI) database of
Autor:
Lawrence J. Whalley, Jian Yang, Neil Pendleton, Antony Payton, Ivar Reinvang, Andrew Pickles, Albert Tenesa, Janie Corley, John M. Starr, Helen C. Fox, Andrea Christoforou, David J. Porteous, Alan J. Gow, D. C. Liewald, Michael A. Horan, Sarah E. Harris, William E R Ollier, Astri J. Lundervold, Paul Redmond, Thomas Espeseth, Paul Haggarty, Gail Davies, Michael E. Goddard, Ian J. Deary, Vidar M. Steen, Lorna M. Lopez, S. Le Hellard, Peter M. Visscher, Kevin A. McGhee, Xiayi Ke, Geraldine McNeill, Michelle Luciano
Publikováno v:
Molecular psychiatry
General intelligence is an important human quantitative trait that accounts for much of the variation in diverse cognitive abilities. Individual differences in intelligence are strongly associated with many important life outcomes, including educatio
Autor:
Richard Adams, S Le Hellard, Pippa A. Thomson, Walter J. Muir, Naomi R. Wray, Andrea Christoforou, David J. Porteous, John C. Whittaker, Albert Tenesa, S. W. Morris, Douglas Blackwood, S L Underwood, Kathryn L. Evans
Publikováno v:
Molecular Psychiatry. 11:384-394
The orphan G protein-coupled receptor 78 (GPR78) gene lies within a region of chromosome 4p where we have previously shown linkage to bipolar affective disorder (BPAD) in a large Scottish family. GPR78 was screened for single-nucleotide polymorphisms