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High Affinity Binding of [3H]Propionyl-[Met(O2)11]Substance P(7–11), a Tritiated Septide-Like Peptide, in Chinese Hamster Ovary Cells Expressing Human Neurokinin-1 Receptors and in Rat Submandibular Glands

Autor: Jacques Glowinski, S. Lavielle, Jean-Claude Beaujouan, Monique Saffroy, G. Chassaing, Sandrine Sagan, Yvette Torrens

Publikováno v: Scopus-Elsevier

Propionyl-[Met(O2)11]substance P(7-11) [ALIE-124 or propionyl-[Met(O2)11]SP(7-11)] has been designed as a septide-like ligand adequate for tritiation and, therefore, adequate for binding studies. In Chinese hamster ovary (CHO) cells expressing human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3526062d311bd5ac4ee00728b6d85ad3
https://doi.org/10.1124/mol.52.1.120

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Competitive Inhibition of N ‐Acetylated‐α‐Linked Acidic Dipeptidase Activity by N ‐Acetyl‐L‐Aspartyl‐β‐Linked L‐Glutamate

Autor: Jacques Glowinski, André Chéramy, Luis Barbeito, V. Serval, S. Lavielle, Anna Pittaluga

Publikováno v: Journal of Neurochemistry. 55:39-46

The endogenous neuropeptide N-acetyl-L-aspartyl-L-glutamate (NAAG) fulfills several criteria required to be accepted as a neurotransmitter. NAAG inactivation may proceed through enzymatic hydrolysis into N-acetyl-L-aspartate and glutamate by an N-ace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36bf9efde41e53154e5266f71ac25a4e
https://doi.org/10.1111/j.1471-4159.1990.tb08818.x

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Analogs of Substance P modified at the C-terminus which are both agonist and antagonist of the NK-1 receptor depending on the second messenger pathway

Autor: E, Sachon, S, Girault-Lagrange, G, Chassaing, S, Lavielle, S, Sagan

Publikováno v: The journal of peptide research : official journal of the American Peptide Society. 59(5)

The initial goal of this study was to analyze, using photolabeling, the interactions between Substance P and its tachykinin NK-1 receptor. Therefore, the photoreactive amino acid para-benzoyl-phenylalanine (pBzl)Phe was incorporated into the Substanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25b354bda8354320b359d52dbd2c8e6b
https://pubmed.ncbi.nlm.nih.gov/11966980

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Use of conformationally constrained peptides for a topographical analysis of the combing site of a monoclonal anti-substance P antibody

Autor: O, Déry, H, Josien, J, Grassi, G, Chassaing, J Y, Couraud, S, Lavielle

Publikováno v: Biopolymers. 39(1)

The topography of the binding site of a monoclonal anti-substance P antibody directed toward the C-terminal pentapeptide of substance P, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, was analyzed further using a wide range of constrained analogues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab51aaf17d1b2c0a4c79c528cfab4d7d
https://pubmed.ncbi.nlm.nih.gov/8924627

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[A new tachykinin receptor revealed by substance P analogues in the guinea pig ileum]

Autor: F, Petitet, J C, Beaujouan, M, Saffroy, Y, Torrens, S, Lavielle, G, Chassaing, D, Loeuillet, J, Glowinski

Publikováno v: Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 314(7)

[Pro9]SP and septide have been described as selective agonists for the SP receptor (NK-1 type). These two peptides contract with a great efficacy the guinea-pig ileum, but unexpectedly septide was practically devoid of affinity for the NK-1 site labe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8103d38e587e7ac738dee2f913f78f2d
https://pubmed.ncbi.nlm.nih.gov/1285414

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Fluorine microimaging and quantification using nuclear reaction analysis: A tool for validating tissue distribution of positron emission tomography tracers

Autor: Richard Ortega, Asuncion Carmona, Gérard Déléris, Stéphane Roudeau, Guillaume Devès, K. Gionnet, S. Lavielle

Publikováno v: Applied Physics Letters
Applied Physics Letters, American Institute of Physics, 2009, 95 (2), pp.023701. ⟨10.1063/1.3173808⟩

An application of ion beam microprobe analysis has been developed for the quantitative imaging of fluorine compounds in biological samples on a micrometer scale. The difficulty of imaging fluorine at trace level concentration in biological tissues ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6715a36c71e9a3dbfbde78d44e04e15
https://doi.org/10.1063/1.3173808

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