Výsledky vyhledávání - "S. L. Shankar"

Mitochondrial abnormalities in neuroectodermal cells stably expressing human amyloid precursor protein (hAPP751)

Autor: S. L. Shankar, A.C. Cuello, R. M. E. Chalmers-Redman, Moshe Szyf, Susan M. Grant, W. G. Tatton

Publikováno v: NeuroReport. 10:41-46

Metabolic hypofunction is a common finding in a number of neurodegenerative diseases, including Alzheimer's disease (AD). The strong linkage between the amyloid precursor protein (APP) and AD led us to examine whether over-expression of this protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b51ffbc6fee037d1bddcaf9def0c69
https://doi.org/10.1097/00001756-199901180-00008

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Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways

Autor: S L, Shankar, S, Mani, K N, O'Guin, E R, Kandimalla, S, Agrawal, B, Shafit-Zagardo

Publikováno v: Journal of neurochemistry. 79(2)

Survivin inhibits apoptosis during development and carcinogenesis and is absent in differentiated cells. To determine whether survivin inhibition induces cell death in neural tumor cells, survivin antisense oligonucleotides (SAO) were administered to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49447999e3a2b41c3d8df506bab088c2
https://pubmed.ncbi.nlm.nih.gov/11677271

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