Zobrazeno 1 - 10
of 12
pro vyhledávání: '"S. L. Neuhausen"'
Autor:
A. W. Adamson, Y. C. Ding, L. Steele, L. A. Leong, R. Morgan, M. T. Wakabayashi, E. S. Han, T. H. Dellinger, P. S. Lin, A. A. Hakim, S. Wilczynski, C. D. Warden, S. Tao, V. Bedell, M. C. Cristea, S. L. Neuhausen
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Background High-grade serous ovarian cancers (HGSCs) display a high degree of complex genetic alterations. In this study, we identified germline and somatic genetic alterations in HGSC and their association with relapse-free and overall surv
Externí odkaz:
https://doaj.org/article/a554d21176a142ac99996e2e44216fb8
Publikováno v:
Journal of medical genetics. 41(2)
The prevalence of BRCA1 and BRCA2 mutations in families with breast and ovarian cancers depends on the type of cancer found, the number of cases, and the ethnic background of the family.1 The proportion of breast cancers attributable to BRCA1 or BRCA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293c524bdc428dfe5ac96f6b5fa16012
https://pubmed.ncbi.nlm.nih.gov/14757871
https://pubmed.ncbi.nlm.nih.gov/14757871
Autor:
A, Hadjisavvas, S L, Neuhausen, M D, Hoffman, A, Adamou, R F, Newbold, K C, Kyriacou, C G, Christodoulou
Publikováno v:
Anticancer research. 21(5)
Germline mutations in the BRCA1 gene are causative for a variable number of hereditary breast/ovarian cancers. The data presented in this study are based on genetic analysis of the BRCA1 gene in 49 DNA samples from breast cancer patients with a posit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aab734e904a525a9a970e5b7a21c6de7
https://pubmed.ncbi.nlm.nih.gov/11848488
https://pubmed.ncbi.nlm.nih.gov/11848488
Autor:
T R, Rebbeck, Y, Wang, P W, Kantoff, K, Krithivas, S L, Neuhausen, A K, Godwin, M B, Daly, S A, Narod, J S, Brunet, D, Vesprini, J E, Garber, H T, Lynch, B L, Weber, M, Brown
Publikováno v:
Cancer research. 61(14)
Women who have inherited a germ-line mutation in the BRCA1 or BRCA2 (BRCA1/2) genes have a greatly increased risk of developing breast cancer compared with the general population. However, there is also substantial interindividual variability in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44238e0716db1062633b0e380d71f542
https://pubmed.ncbi.nlm.nih.gov/11454686
https://pubmed.ncbi.nlm.nih.gov/11454686
Publikováno v:
American journal of medical genetics. 98(1)
Celiac disease is an autoimmune gastrointestinal disorder characterized by mucosal atrophy of the jejunum on exposure to gluten, a protein found in grains. The purpose of our study was to determine the prevalence of celiac disease in children with Do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7255881bcc87a50c959900630c72399
https://pubmed.ncbi.nlm.nih.gov/11426458
https://pubmed.ncbi.nlm.nih.gov/11426458
Autor:
S L, Neuhausen
Publikováno v:
Cancer. 86
Ethnic differences in cancer incidence and mortality exist and are probably the result of genetic and epidemiological risk factors. Genetic differences caused by founder mutations are reviewed, with special emphasis on mutations in BRCA1 and BRCA2. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66023405d2dd5995ef20738b079245f5
https://pubmed.ncbi.nlm.nih.gov/10630184
https://pubmed.ncbi.nlm.nih.gov/10630184
Autor:
S A, Narod, J S, Brunet, P, Ghadirian, M, Robson, K, Heimdal, S L, Neuhausen, D, Stoppa-Lyonnet, C, Lerman, B, Pasini, P, de los Rios, B, Weber, H, Lynch
Women with a mutation in BRCA1 or BRCA2 have a high risk of developing breast cancer and of contralateral cancer after the initial diagnosis of breast cancer. Tamoxifen protects against contralateral breast cancer in the general population, but wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::02d424914303188e1c2efb95d47e9a0c
http://hdl.handle.net/2318/37598
http://hdl.handle.net/2318/37598
Autor:
C M, Lewis, S L, Neuhausen, D, Daley, F J, Black, J, Swensen, R W, Burt, L A, Cannon-Albright, M H, Skolnick
Publikováno v:
Cancer research. 56(6)
Colorectal cancer (CRC) has a strong familial component. Candidate genes for colorectal cancer have been identified through mutations in four mismatch repair genes (hMSH2, hMLH1, hPMS1, and hPMS2) and genes that are deleted or mutated in tumors (DCC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2e9591be552e2c78dfee6904566ea39
https://pubmed.ncbi.nlm.nih.gov/8640829
https://pubmed.ncbi.nlm.nih.gov/8640829
Autor:
R S, Cornelis, S L, Neuhausen, O, Johansson, A, Arason, D, Kelsell, B A, Ponder, P, Tonin, U, Hamann, A, Lindblom, P, Lalle
Publikováno v:
Genes, chromosomescancer. 13(3)
Loss of heterozygosity (LOH) was evaluated in 174 breast and ovarian tumors derived from 94 families with at least 3 first-degree relatives affected with either of these cancers. By linkage analysis 26 families were identified as having a high poster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50517554c612a5df42ecc73831fa97c2
https://pubmed.ncbi.nlm.nih.gov/7669740
https://pubmed.ncbi.nlm.nih.gov/7669740
Autor:
D E, Goldgar, S L, Neuhausen, L, Steele, P, Fields, J H, Ward, T, Tran, K, Ngyuen, M R, Stratton, D F, Easton
Publikováno v:
Journal of the National Cancer Institute. Monographs. (17)
Interest in the genetics of breast cancer has intensified with the discovery of a breast cancer susceptibility locus, BRCA1, on chromosome 17q. In this paper, we describe updated information on a large breast cancer kindred (K107) that has been exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e494e74f58a873cab49711e516320def
https://pubmed.ncbi.nlm.nih.gov/8573446
https://pubmed.ncbi.nlm.nih.gov/8573446