Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S. L. Griffiths"'
Autor:
D. Popovic, C. Weyer, A. Ruef, D. Dwyer, S. L. Griffiths, P. A. Lalousis, N. Koutsouleris, R. Upthegrove
Publikováno v:
European Psychiatry, Vol 67, Pp S45-S47 (2024)
Introduction An early and comprehensive neurobiological characterization of severe mental disorders could elucidate mechanistic pathways, aid the development of novel therapeutics, and therefore enable timely and targeted intervention in at-risk yout
Externí odkaz:
https://doaj.org/article/3f3ce8f079dd4553a4529ad636ad8169
Autor:
Gary Sweeney, Yvonne M. Horton, James Pryde, Eric K. Y. Tang, Fiona MacDonald, Callum Livingstone, S L Griffiths, Nicholas J. Morris, M Lobban, Miles D. Houslay, Grant Scotland, Yasmin Shakur
Publikováno v:
Europe PubMed Central
22. Milligan, G., Unson, C. G. & Wakelam, M. J. 0. (1989) Biochem. J. 262,643-649 Mitchell, F. M., Mullaney, I., Godfrey, P. P., Arkinstall, S. J.? Wakelam, M. J. 0. & Milligan, G. (1991) FEHS 1,ett. 287, 171-174 McFadzean, I., Mullaney, I., Brown, L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e56cb5a0c2d9a8fc58c5356851febe
https://doi.org/10.1042/bst0200140
https://doi.org/10.1042/bst0200140
Autor:
M Bushfield, John T. Knowler, Miles D. Houslay, Graeme Milligan, S L Griffiths, Gregory J. Murphy, Peter J. Parker, S Mollner, Nigel J. Pyne
Publikováno v:
Europe PubMed Central
Levels of the G-protein alpha-subunits alpha-Gi-2, alpha-Gi-3 and the 42 kDa, form of alpha-Gs were markedly decreased in hepatocyte membranes from streptozotocin-diabetic animals as compared with normals. In contrast, no detectable changes in alpha-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9469f4425263b3f3278eba792a6376c9
https://doi.org/10.1042/bj2710365
https://doi.org/10.1042/bj2710365
Autor:
Craig J. Daly, Moira A. Wilson, Ailsa M. Campbell, Miles D. Houslay, L. Pooley, James Beattie, S L Griffiths, M Lobban, Yasmin Shakur
Publikováno v:
Europe PubMed Central
An antiserum was generated against a dodecapeptide whose sequence is found at the C-terminus of a cyclic AMP (cAMP)-specific, type-IVA phosphodiesterase encoded by the rat ‘dunc-like’ cyclic AMP phosphodiesterase (RD1) cDNA. This antiserum identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8e8866f1352b26d97ef5cd5f05cc4e
https://pubmed.ncbi.nlm.nih.gov/7702577
https://pubmed.ncbi.nlm.nih.gov/7702577
Publikováno v:
European journal of biochemistry. 193(2)
Synthetic oligonucleotide probes were designed to detect the alpha-subunits of the guanine-nucleotide-regulatory proteins (G-proteins) Gi-1, Gi-2, Gi-3 and Gs (Gi is inhibitory and Gs is stimulatory). Each probe detected a single major mRNA species i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b062627eb33fa8a419c1f708b86ad1
https://pubmed.ncbi.nlm.nih.gov/1699758
https://pubmed.ncbi.nlm.nih.gov/1699758
Autor:
Miles D. Houslay, S L Griffiths
Publikováno v:
Biochemical Society transactions. 18(3)
0 5 1.15 1.25 Density (g cm ') of G,a from cell membranes has been observed in L6 skeletal myoblasts treated with cholera toxin to ADP ribosylate the G-proteins [7], although under these conditions the G ,a lost from the plasma membrane was not detec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6219341bbfa179cacf2b9eaaa0d36b1
https://pubmed.ncbi.nlm.nih.gov/2115472
https://pubmed.ncbi.nlm.nih.gov/2115472
Autor:
Graeme Milligan, S L Griffiths, E D Saggerson, John T. Knowler, F M Mitchell, Miles D. Houslay
Publikováno v:
Europe PubMed Central
Considerable debate has focused on the molecular identity of the guanine-nucleotide-binding proteins (G-proteins) in adipose tissue which can be detected following pertussis-toxin-catalysed ADP-ribosylation [Rapiejko, Northup, Evans, Brown & Malbon (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237b868527d67b3b1022ba38b4fc5dab
https://doi.org/10.1042/bj2620403
https://doi.org/10.1042/bj2620403
Autor:
Kenneth Siddle, B E Lavan, S Spence, Mary-Anne McGregor, Graeme Milligan, John T. Knowler, Miles D. Houslay, Gregory J. Murphy, Richard M. O'Brien, Derek Strassheim, Andrew Wilson, Neil G. Anderson, Mark K. Saville, Mary D. Woods, Timothy M. Palmer, Elaine Kilgour, S L Griffiths, Nigel J. Pyne
Publikováno v:
Europe PubMed Central
T h e detailed pathways which link occupancy of the insulin receptor with actions on target cells remain t o be defined. The insulin receptor expresses a tyrosyl kinase activity for which considerable evidence has accrued indicating that it plays a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f277fe9cbdabb61371f490c6e1c381fe
https://pubmed.ncbi.nlm.nih.gov/2504628
https://pubmed.ncbi.nlm.nih.gov/2504628
Publikováno v:
The Biochemical journal. 238(2)
125I-labelled heat-labile toxin (from Escherichia coli) and 125I-labelled cholera toxin bound to immobilized ganglioside GM1 and Balb/c 3T3 cell membranes with identical specificities, i.e. each toxin inhibited binding of the other. Binding of both t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be770d395e0a2075bab628af5ae45e82
https://pubmed.ncbi.nlm.nih.gov/3541910
https://pubmed.ncbi.nlm.nih.gov/3541910