Výsledky vyhledávání - "S. L. Blethen"

Weight Relative to Height Before and During Growth Hormone Therapy in Prepubertal Children

Autor: A C Rundle, S L Blethen, P B Kaplowitz

Publikováno v: Hormone and Metabolic Research. 30:565-569

We used the Genentech National Cooperative Growth Study database to examine differences in weight relative to height (weight for height standard deviation score or WTHTZ) in 3460 patients at enrollment and after one year of therapy with recombinant h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce7d0a67ad9817451276b564bbc2069
https://doi.org/10.1055/s-2007-978934

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Safety of recombinant deoxyribonucleic acid-derived growth hormone: The National Cooperative Growth Study experience

Autor: S. L. Blethen

Publikováno v: Journal of Clinical Endocrinology & Metabolism. 81:1704-1710

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cb5bbefcf72024fe47436f42ef19b7b
https://doi.org/10.1210/jc.81.5.1704

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Circulating growth hormone isoforms in girls with Turner's syndrome

Autor: S. L. Blethen

Publikováno v: Journal of Clinical Endocrinology & Metabolism. 78:1439-1443

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4482e49846f868e8a52ad32aaa59a02c
https://doi.org/10.1210/jc.78.6.1439

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Factors predicting the response to growth hormone (GH) therapy in prepubertal children with GH deficiency

Autor: S. L. Blethen

Publikováno v: Journal of Clinical Endocrinology & Metabolism. 76:574-579

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8875cba9d30275cc031633eb2ca2a469
https://doi.org/10.1210/jc.76.3.574

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Pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient children

Autor: S. F. Kemp, P. J. Fielder, K. M. Attie, S. L. Blethen, E. O. Reiter, K. M. Ford, M. Marian, L. N. Dao, H. J. Lee, P. Saenger

Publikováno v: The Journal of clinical endocrinology and metabolism. 89(7)

Long-term GH replacement therapy is indicated for children with growth failure due to GH deficiency (GHD). We evaluated the feasibility of administering a long-acting GH preparation [Nutropin Depot (somatropin, rDNA origin) for injectable suspension]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e226c98b179e8ec13c23a57aa1ac9b3
https://pubmed.ncbi.nlm.nih.gov/15240597

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Early initiation of growth hormone treatment allows age-appropriate estrogen use in Turner's syndrome

Autor: E O, Reiter, S L, Blethen, J, Baptista, L, Price

Publikováno v: The Journal of clinical endocrinology and metabolism. 86(5)

Because estrogen (E) accelerates skeletal maturation it can decrease final height attainable with GH therapy in girls with Turner's syndrome (TS). Nonetheless, as age-appropriate E administration does have psychobehavioral benefits for such patients,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::52487dcbe4f94f127340ebbe8b8116cd
https://pubmed.ncbi.nlm.nih.gov/11344188

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Growth hormone stimulation test results as predictors of recombinant human growth hormone treatment outcomes: preliminary analysis of the national cooperative growth study database

Autor: G M, Bright, J R, Julius, J, Lima, S L, Blethen

Publikováno v: Pediatrics. 104(4 Pt 2)

Growth hormone (GH) stimulation tests are considered a prerequisite to clinical trials of recombinant human GH (rhGH) therapy, but the test results may not be predictive of the treatment outcomes with rhGH. We examined the GH stimulation test results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05864f8861c6da468ef66a479c78ea1d
https://pubmed.ncbi.nlm.nih.gov/10506258

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Combined use of growth hormone and gonadotropin-releasing hormone analogues: the national cooperative growth study experience

Autor: B, Kohn, J R, Julius, S L, Blethen

Publikováno v: Pediatrics. 104(4 Pt 2)

Gonadotropin-releasing hormone ana-logues (GnRHa) are used to treat central precocious puberty. They also are used to delay puberty in short children with a prognosis for impaired adult height. In both cases, growth hormone (GH) treatment is sometime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbc2146f540ee8271b7e369bef9117e1
https://pubmed.ncbi.nlm.nih.gov/10506254

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The role of serial sampling in the diagnosis of growth hormone deficiency

Autor: F B, Diamond, E V, Jorgensen, A W, Root, D I, Shulman, J P, Sy, S L, Blethen, B B, Bercu

Publikováno v: Pediatrics. 102(2 Pt 3)

We analyzed 12-hour serial sampling of growth hormone (GH) levels in two cohorts of short children: 96 children referred to a university endocrine clinic or studied on a research protocol and 825 children in the National Cooperative Growth Study of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f21ce3cd883cdab728355772f9a34f2d
https://pubmed.ncbi.nlm.nih.gov/9685457

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Response to growth hormone in attention deficit hyperactivity disorder: effects of methylphenidate and pemoline therapy

Autor: J K, Rao, J R, Julius, T J, Breen, S L, Blethen

Publikováno v: Pediatrics. 102(2 Pt 3)

To determine whether treatment of attention deficit hyperactivity disorder (ADHD) with methylphenidate hydrochloride or pemoline diminishes the response to growth hormone (GH) therapy in patients with idiopathic GH deficiency (IGHD) or idiopathic sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fcedd4d05bf84db202342cd7d134ad16
https://pubmed.ncbi.nlm.nih.gov/9685452

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