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pro vyhledávání: '"S. L. Bielas"'
Autor:
C. W. Ryan, S. L. Regan, E. F. Mills, B. T. McGrath, E. Gong, Y. T. Lai, J. B. Sheingold, K. Patel, T. Horowitz, A. Moccia, Y. C. Tsan, A. Srivastava, S. L. Bielas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Polycomb repressive complex 1 (PRC1) modifies chromatin through catalysis of histone H2A lysine 119 monoubiquitination (H2AK119ub1). RING1 and RNF2 interchangeably serve as the catalytic subunit within PRC1. Pathogenic missense variants in P
Externí odkaz:
https://doaj.org/article/f80289b205214743a39021e064e5f307
