Zobrazeno 1 - 10 of 12 pro vyhledávání: '"S. L. Beam"'
1
Combined-type osteosarcoma in a rhesus macaque
Autor: S. L. Beam
Publikováno v: Veterinary pathology. 42(3)
A femoral mass from a 15-year-old rhesus macaque was evaluated. Grossly, the mass consisted of a large, osteolytic focus in the distal femur, a gelatinous core of neoplastic tissue in the medullary cavity, and an invasive mass-obliterating musculatur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c026e732ee4dbc9ea4d44d035b84277
https://pubmed.ncbi.nlm.nih.gov/15872388
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3
An immunohistochemical study of cyclooxygenase-2 expression in various feline neoplasms
Autor: Sean P. McDonough, Antony S. Moore, Kenneth M. Rassnick, S. L. Beam
Publikováno v: Veterinary pathology. 40(5)
Cyclooxygenase (COX) enzymes catalyze the synthesis of prostaglandins and exist as two isoforms, COX-1 and COX-2. COX-2 is a potent inducible mediator of inflammation. COX-2 is also upregulated in several human tumors and in canine squamous cell, ren
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::796cba91dcfc84e895ccd7f9656a453c
https://pubmed.ncbi.nlm.nih.gov/12949405
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4
Biological factors in human cutaneous melanoma correlated to disease stage
Autor: W. J. Culpepper, J. N. Broussard, J. H. Hasskamp, S. L. Beam, E. C. McCarron, Bhuvnesh K. Sharma, E. G. Elias, John L. Zapas, A. M. Avergas
Publikováno v: Journal of Clinical Oncology. 27:9053-9053
9053 Background: Cutaneous melanoma cells express a variety of cytokines and growth factors (C/GF) as the tumor progresses. This study was undertaken to identify various C/GF at different stages of the disease with the hope of identifying prognostic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22e9acbf2207aafc26834c19ee2a69a5
https://doi.org/10.1200/jco.2009.27.15_suppl.9053
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5
GM-CSF & IL-2 ± autologous whole cell vaccine as adjuvant therapy in cutaneous melanoma: A phase II clinical trial
Autor: E. G. Elias, W. J. Culpepper, John L. Zapas, E. C. McCarron, J. H. Hasskamp, S. L. Beam
Publikováno v: Journal of Clinical Oncology. 26:20027-20027
20027 Background: The results of various adjuvant trials in high-risk melanoma patients have demonstrated significant improvement in survival, but the results have been inconsistent. GM-CSF and IL-...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8cecb5607d2c3e88dcafde57a70007e
https://doi.org/10.1200/jco.2008.26.15_suppl.20027
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6
Changing behavior of cutaneous melanoma
Autor: John L. Zapas, E. C. McCarron, E. G. Elias, S. L. Beam, Bhuvnesh K. Sharma, J. H. Hasskamp
Publikováno v: Journal of Clinical Oncology. 26:22197-22197
22197 Background: The non-surgical management of cutaneous melanoma remains blighted by poor and variable results. Cytokines and growth factors (Factors) at the tumor site may act as autocrines and...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c162ff17f58c2299f566acfdcd18c809
https://doi.org/10.1200/jco.2008.26.15_suppl.22197
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7
A simplified staging system in cutaneous melanoma to select patients for adjuvant trials
Autor: S. L. Beam, E. G. Elias
Publikováno v: Journal of Clinical Oncology. 25:19003-19003
19003 Background: Most clinical trials with adjuvant therapy in melanoma concentrate on high-risk patients including those with metastases to regional lymph nodes (LN), stage III and locally advanced T4, i.e., stage IIB and IIC. These trials may be m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc0ccadc1c3ade516d2c0ea4449dfa68
https://doi.org/10.1200/jco.2007.25.18_suppl.19003
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8
Granulocyte-macrophage colony stimulating factor (GM-CSF) & Interleukin-2 (IL-2) combination as adjuvant therapy in cutaneous melanoma. Early results of a phase II clinical trial
Autor: E. G. Elias, S. L. Beam, S. D. Brown, John L. Zapas
Publikováno v: Journal of Clinical Oncology. 22:7559-7559
7559 Background: GM-CSF leads to dendritic cell priming and activation, and also increases IL-2 receptor expression on T-lymphocytes. IL-2 creates LAK cells and TIL cells. Therefore, it was compelling to combine these 2 agents, each with a different
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e7c962a86fc7e146982fa77c89a02ed
https://doi.org/10.1200/jco.2004.22.90140.7559
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9
The effects of systemic granulocyte-macrophage colony stimulating factor (GM-CSF) and Interleukin-2 (IL-2) on peripheral blood dendritic cell (DC) counts in patients with stage IIB-IV melanoma
Autor: S. D. Brown, John L. Zapas, S. L. Beam, E. G. Elias, K. A. Jablonski, J. H. Hasskamp
Publikováno v: Journal of Clinical Oncology. 22:2611-2611
2611 Background: In an attempt to provide more effective adjuvant systemic therapy in Stages IIB-IV melanoma, we chose to study a sequential regimen of GM-CSF, 125 μg/m2 for 14 days, followed by IL-2, 9 million IU/m2 for 4 days followed by a 10 day
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24cf2d3d3440527700b73449026cabae
https://doi.org/10.1200/jco.2004.22.90140.2611
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