Zobrazeno 1 - 10 of 11 pro vyhledávání: '"S. L. Abrams"'
1
GSK-3β can regulate the sensitivity of pancreatic cells to chemotherapeutic drugs, targeted therapeutics and nutraceuticals
Autor: S. L. Abrams, S. M. Akula, A. K Meher, L. S. Steelman, A. Gizak, P. Duda, D. Rakus, A. M. Martelli, S. Ratti, L. Cocco, G. Montalto, M. Cervello, P. Ruvolo, M. Libra, L. Falzone, S. Candido, J. A. McCubrey.
Glycogen synthase kinase-3 (GSK-3) is a regulator of signaling pathways. KRas is frequently mutated in pancreatic cancers. The growth of certain pancreatic cancers is KRas-dependent and can be suppressed by GSK-3 inhibitors, documenting a link betwee
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::ff10e8f2f8eb627ea56477a5983b746a
http://hdl.handle.net/11585/855456
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2
Introduction of WT-TP53 into pancreatic cancer cells with mutant TP53 alters sensitivity of chemotherapeutic drugs, targeted therapeutics and nutraceuticals
Autor: S. L. Abrams, K. Lertpiriyapong, L. V. Yang, A. M. Martelli, L. Cocco, S. Ratti, M. Falasca, R. M. Murata, P. L. Rosalen, P. Lombardi, M. Libra, G. Montalto, M. Cervello, L. S. Steelman, J. A. McCubrey.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, highly metastatic malignancy and accounts for 85% of pancreatic cancers. PDAC patients have poor prognosis with a five-year survival of only 5–10%. Mutations at the TP53 gene are readily det
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::5a84a3be8cae184498f98940ecc77b62
http://hdl.handle.net/11585/643928
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3
Drug-resistance in FL5.12 doxorubicin-resistant hematopoietic cells: elevated MDR1 and decreased BCL2-family member expression and increased side-population positive cells
Autor: L. S. Steelman, S. L. Abrams, P. Ruvolo, V. Ruvolo, L. Cocco, S. Ratti, A. M. Martelli, L. Neri, S. Candido, M. Libra, J. A. McCubrey.
Chemotherapeutic drug treatment can result in the emergence of drug-resistant cells. By culturing an interleukin-3 (IL-3)-dependent cell line, FL5.12 cells in the presence of the chemotherapeutic drug doxorubicin, we isolated FL/Doxo cells which are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::98fe6a00ba8d6508c18214abde8fcf01
http://hdl.handle.net/11585/619773
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5
Congenital vertebral malformations: prenatal diagnosis using ultrasonography
Autor: S L Abrams, R A Filly
Publikováno v: Radiology. 155(3)
We present a case of multiple, congenital vertebral malformations diagnosed in utero. The normal and abnormal sonographic appearance of the fetal vertebral bodies is described. The classification of vertebral anomalies, their complications, and assoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa83c7aadf81b2e73e306d8ce30b7ae
https://pubmed.ncbi.nlm.nih.gov/3890005
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6
Curvature of the fetal femur: a normal sonographic finding
Autor: R A Filly, S L Abrams
Publikováno v: Radiology. 156(2)
Perception of the fetal femur in the far field as curved is common in sonographic studies. The mild concavity of the medial aspect of the femoral diaphysis accounts for this apparent curvature, which should not be mistaken for fetal abnormality.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a3f62117de78a161a67aa0539e318e
https://pubmed.ncbi.nlm.nih.gov/3892579
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8
Umbilical vein thrombosis: sonographic detection in utero
Autor: Peter W. Callen, S L Abrams, R A Filly
Publikováno v: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 4(6)
Umbilical vein thrombosis is associated with a high perinatal mortality and is seen most often with compression, torsion, stricture, or hematoma of the umbilical cord. Three cases of umbilical vein thrombosis detected on obstetrical ultrasound scans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee53a7137dda1b21cd14bb614f78a5d5
https://pubmed.ncbi.nlm.nih.gov/3892025
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