Identification of aspirin analogues that repress NF-κB signalling and demonstrate anti-proliferative activity towards colorectal cancer in vitro and in vivo

Autor: Steven T. Russell, Christopher J. Perry, Lesley A. Stark, Iain D. Nicholl, Ann-Katrin Claudius, Kerry Guest, Chandra S. Kankipati, Rajagopal Sharada Kilari, Sadiya Hassan

Publikováno v: Oncology Reports. 32:1670-1680

Substantial evidence indicates that aspirin and related non-steroidal anti-inflammatory drugs (NSAIDs) have potential as chemopreventative/therapeutic agents. However, these agents cannot be universally recommended for prevention purposes due to thei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8599f2cb41f27b78fd2adc8e5d35a650
https://doi.org/10.3892/or.2014.3373

Abstract 335: Aspirin, di-aspirin and their toxicity to colorectal cancer

Autor: Iain D. Nicholl, Chandra S. Kankipati, Christopher J. Perry

Publikováno v: Cancer Research. 74:335-335

Introduction The lifetime risk for developing colorectal cancer (CRC) is approximately 7%. In the USA over 140,000 people a year develop CRC, with approximately 51,000 deaths/year. Epidemiological studies indicate that long-term aspirin usage reduces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f1e1e012ae9a2f97f7af1634e1d1dbb
https://doi.org/10.1158/1538-7445.am2014-335

The incidence of prostate cancer in patients under the age of 60 from an urban setting

Autor: Robert A. Somer, C. Dalsania, V. Khemka, R. Parra, M. Shum, E. Bodofsky, S. Kankipati, S. Dibiase, Z. Skaff, M. El-Khoury

Publikováno v: Journal of Clinical Oncology. 24:14622-14622

14622 Background: Although the risk for developing prostate cancer increases with age, few studies have reported the incidence of prostate cancer in men younger than 60 from an urban setting. Methods: All patients diagnosed and treated for prostate c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bfac0241c18107246aa47ffc4fdaf2e
https://doi.org/10.1200/jco.2006.24.18_suppl.14622

Bacterial Proteins and Peptides as Potential Anticancer Agents: A Novel Search for Protein-based Therapeutics.

Autor: Pyla M; Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad - 500075, Telangana, India., Kankipati S; Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad - 500075, Telangana, India., Sumithra B; Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad - 500075, Telangana, India., Mishra PK; Department of Botany, B. N. College, Dhubri-783324, Assam, India., Mishra B; Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad - 500075, Telangana, India., Mandal SK; Department of Biotechnology, Chaitanya Bharathi Institute of Technology (CBIT), Gardipe, Hyderabad - 500075, Telangana, India., Panda J; Nanobiotechnology and Translational Knowledge Laboratory, Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Techno City, 9th Mile, Baridua-- 793101, Ri-Bhoi, Meghalaya, India., Chopra H; Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai-602105, Tamil Nadu, India., Satya Kumar A; Natural and Medical Sciences Research Centre, University of Nizwa, Nizwa, 616, Oman., Salah M; Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig44519, Egypt., Mohanta YK; Nanobiotechnology and Translational Knowledge Laboratory, Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM), Techno City, 9th Mile, Baridua-- 793101, Ri-Bhoi, Meghalaya, India., Kamal MA; King Fahd Medical Research Center, King Abdulaziz University, Saudi Arabia.; Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, China.; Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Bangladesh.; Enzymoics, 7 Peterlee place, Hebersham, NSW 2770; Novel Global Community Educational Foundation, Australia.

Publikováno v: Current medicinal chemistry [Curr Med Chem] 2024 Feb 07. Date of Electronic Publication: 2024 Feb 07.