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Maximizing retention in long-term clinical trials of a weight loss agent: use of a dietitian support team

Autor: A. Digenio, Robert Chew, S. S. Klioze, Linda M. Delahanty, R. D. England, M. Riggs

Publikováno v: Obesity Science & Practice. 2:256-265

SummaryObjective High-attrition rates have been observed in long-term clinical trials of weight loss agents. We evaluated the impact of an innovative retention programme on 1-year retention. Methods Three Phase 3 global multicentre clinical trials ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc6cb58ef351a07247a68f3a189f090c
https://doi.org/10.1002/osp4.57

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Efficacy and Safety of CP-945,598, a Selective Cannabinoid CB1 Receptor Antagonist, on Weight Loss and Maintenance

Autor: Nick Finer, John D. Obourn, Richard D. England, Priscilla Hollander, Solomon S. Klioze, Robert J. Fountaine, Louis J. Aronne, Robert Chew, Coralie M. Powell

Publikováno v: Obesity. 19:1404-1414

Three double-blind, placebo-controlled, three-parallel-group, multicenter phase 3 trials were conducted to assess the efficacy and safety of CP-945,598 for weight loss and weight-loss maintenance. Two trials were designed to be 2 years in duration (i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6308da5ae8071be96414dd7839a6be5a
https://doi.org/10.1038/oby.2010.352

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Two-Year Pulmonary Safety and Efficacy of Inhaled Human Insulin (Exubera) in Adult Patients With Type 2 Diabetes

Autor: Julio Rosenstock, William T. Cefalu, Priscilla A. Hollander, Andre Belanger, Freddy G. Eliaschewitz, Jorge L. Gross, Solomon S. Klioze, Lisa B. St. Aubin, Howard Foyt, Masayo Ogawa, William T. Duggan

Publikováno v: Diabetes Care

OBJECTIVE—The purpose of this study was to evaluate the 2-year pulmonary safety of inhaled human insulin (Exubera [EXU]) in 635 nonsmoking adults with type 2 diabetes. RESEARCH DESIGN AND METHODS—Patients were randomly assigned to receive prandia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab49da0a8758cf51d14d52b70a0c05f
http://europepmc.org/articles/PMC2518332

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Two-Year Safety and Efficacy of Inhaled Human Insulin (Exubera) in Adult Patients With Type 1 Diabetes

Autor: Masayo Ogawa, Howard Foyt, Julio Rosenstock, Solomon S. Klioze, Priscilla A. Hollander, Freddy G. Eliaschewitz, Lisa St Aubin, William T. Cefalu, Jorge Luiz Gross, André Bélanger, William T. Duggan

Publikováno v: Diabetes Care. 30:579-585

OBJECTIVE—The purpose of this study was to evaluate the long-term (2-year) safety and efficacy of inhaled human insulin (Exubera [insulin human (rDNA origin)] inhalation powder) (EXU) in adult patients with type 1 diabetes. RESEARCH DESIGN AND METH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51eb05041ddf6ce45a37f35308d339c
https://doi.org/10.2337/dc06-1863

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Tiotropium in patients with moderate COPD naive to maintenance therapy: a randomised placebo-controlled trial

Autor: Frank C. Sciurba, Nikos M Siafakas, Thierry Troosters, Santosh Sutradhar, Marc Decramer, Solomon S. Klioze, Idelle Weisman, Carla Yunis

Publikováno v: NPJ Primary Care Respiratory Medicine

The benefits of pharmacotherapy with tiotropium HandiHaler 18 μg for patients with chronic obstructive pulmonary disease (COPD) have been previously demonstrated. However, few data exist regarding the treatment of moderate disease (Global Initiative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3b5f9946ecf19387f723bc4f160265
https://lirias.kuleuven.be/handle/123456789/455216

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