Zobrazeno 1 - 10
of 69
pro vyhledávání: '"S. K. Kotovskaya"'
Autor:
S. Ya. Loginova, V. N. Schukina, S. V. Savenko, V. V. Rubtsov, S. V. Borisevich, D. L. Chizhov, G. L. Rusinov, E. V. Verbitskiy, V. N. Charushin, S. K. Kotovskaya, V. L. Rusinov
Publikováno v:
Антибиотики и Химиотерапия, Vol 69, Iss 3-4, Pp 21-30 (2024)
Background. The COVID-19 pandemic, caused by the SARS-CoV-2 coronavirus, originated in Wuhan, China, has claimed millions of lives around the world. In this regard, the search for effective drugs, including the repurposing of existing ones, has becom
Externí odkaz:
https://doaj.org/article/9660279325d74f5aa1e3941ad160ac4b
Autor:
S. YA. Loginova, S. V. Borisevich, B. A. Maksimov, V. P. Bondarev, S. K. Kotovskaya, V. L. Rusinov, V. N. Charushin, O. N. Chupakhin
Publikováno v:
Антибиотики и Химиотерапия, Vol 55, Iss 9-10, Pp 25-28 (2020)
The experimental study of the prophylactic efficacy of Triazaverin against the experimental form of the influenza virus A (H5N1) on albino mice intranasally infected with the influenza virus A/Chicken/Kurgan/Russia/02/05 vs. the reference drugs Tamif
Externí odkaz:
https://doaj.org/article/2f9d299f484345cb9353cf64de3cf8d0
Autor:
S. A. Loginova, S. V. Borisevich, V. A. Maksimov, V. P. Bondarev, S. K. Kotovskaya, V. L. Rusinov, V. N. Charushkin, O. N. Chupakhin
Publikováno v:
Антибиотики и Химиотерапия, Vol 56, Iss 1-2, Pp 10-12 (2020)
Therapeutic activity of Triazavirin against experimental influenza A was studied on albino mice intranazally infected with influenza virus A/Chicken/Kurgan/Russia/02/05 (H5N1) vs. reference drugs (Oseltamivir, Remantadin and Arbidol®). The study sho
Externí odkaz:
https://doaj.org/article/8a32695f701441af840a7bb153b08fb1
Autor:
A. V. Baklykov, A. A. Tumashov, S. K. Kotovskaya, E. N. Ulomskiy, G. L. Rusinov, V. L. Rusinov, D. S. Kopchuk, O. N. Chupakhin, V. N. Charushin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 4, Pp 98-102 (2019)
A procedure for the simantenous determination of aminotriazole, triazolopyrimidinone and nirotriazolopyrimidinone was developed using the HPLC method with UV detection. To achieve the best chromatographic characteristics, it is proposed to use a colu
Externí odkaz:
https://doaj.org/article/1fa4287d9c6241f3b8f27892ed268400
Autor:
A. V. Baklykov, A. A. Tumashov, S. K. Kotovskaya, E. N. Ulomskiy, G. L. Rusinov, V. L. Rusinov, O. N. Chupahin, V. N. Charushin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 146-150 (2019)
Method of simultaneous determination of aminotriazole and triazolopyrimidinone using HPLC with UV-detection was developed. For best chromatographic performance Zorbax NH2 amino phase column (Agilent Technologies, USA) was selected. The applicability
Externí odkaz:
https://doaj.org/article/492edb3153cc409bb1a211790a3ca486
Autor:
E. G. Deyeva, Yu. I. Shevchik, A. A. Shaldghan, K. A. Zagorodnikova, A. A. Tumashov, A. V. Baklykov, S. K. Kotovskaya, O. N. Chupahin, V. N. Charushin, V. L. Rusinov, D. S. Kopchuk
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 3, Pp 172-180 (2019)
The paper contains а results of the study of the pharmacokinetics, tolerability and safety of a new influenza drug Triazide in several dose regimens conducted on healthy volunteers. The convenient method for the determining the Triazide in blood pla
Externí odkaz:
https://doaj.org/article/40894e12a0b44763b2c48a47d8af313f
Autor:
A. V. Baklykov, A. A. Tumashov, S. K. Kotovskaya, E. N. Ulomsky, G. L. Rusinov, V. L. Rusinov, G. A. Artem’ev, D. S. Kopchuk, V. N. Charushin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 78-83 (2019)
A procedure for quantitative determination of 5-methyl-6-nitro-7-oxo-1,2,4-triazolo[1,5-a]pirimidinide l -argininy was developed using the HPLC method with UV detection. To achieve the best chromatographic characteristics, it is proposed to use a col
Externí odkaz:
https://doaj.org/article/ebf6dce434b24def95aa312d1ae2d3b3
Autor:
K. V. Savateev, V. L. Rusinov, S. K. Kotovskaya, A. A. Spasov, L. V. Naumenko, A. S. Taran, A. A. Brigadirova, D. S. Yakovlev, K. T. Sultanova, N. M. Shcherbakova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:777-782
Abstract Six compounds of the 5(7)-alkylamino-6-nitroazolopyrimidine and 8-alkylazolo[5,1-b]purine series were selected based on the structural analysis of A1 adenosine receptor inhibitors and the role of this biological target in the modulation of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55f29fa1a7166a2130548f971eaaa375
https://doi.org/10.1134/s1068162022040185
https://doi.org/10.1134/s1068162022040185
Autor:
Vladimir L. Rusinov, K. V. Savateev, S. K. Kotovskaya, Oleg N. Chupakhin, Pavel A. Slepukhin, Valery N. Charushin
Publikováno v:
Chemistry of Heterocyclic Compounds
[Figure not available: see fulltext.] An atom-efficient method toward hybrid molecules via azide-alkyne cycloaddition of 7-azido-3-ethoxycarbonyl-1-ethyl-6-fluoroquinolin-4(1H)-one and novel perspective triazolopyrimidines has been developed. This pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d789984a85c816857a81b565191472
https://doi.org/10.1007/s10593-021-02886-7
https://doi.org/10.1007/s10593-021-02886-7
Autor:
Alexander A. Spasov, S. K. Kotovskaya, Vladimir L. Rusinov, V. A. Kosolapov, K. T. Sultanova, M. V. Miroshnikov, Irina M. Sapozhnikova, D. V. Mal’tsev
Publikováno v:
Toxicological Review. :39-43
The article presents the results of a study of the neurotoxicological profile of the new compound AB-19, acting on collagen glycation end products (AGE) and their receptors (RAGE), for the prevention and treatment of diabetes complications. The multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0af7f4e438104ac377f0130ea93333a
https://doi.org/10.36946/0869-7922-2020-4-39-43
https://doi.org/10.36946/0869-7922-2020-4-39-43