Zobrazeno 1 - 7
of 7
pro vyhledávání: '"S. K. E. Koekkoek"'
Autor:
S. Dijkhuizen, L. M. C. Van Ginneken, A. H. C. IJpelaar, S. K. E. Koekkoek, C. I. De Zeeuw, H. J. Boele
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Neuroscience heavily relies on animal welfare in laboratory rodents as it can significantly affect brain development, cognitive function and memory formation. Unfortunately, laboratory animals are often raised in artificial environments devo
Externí odkaz:
https://doaj.org/article/e3f84ab3f264415daa00b06bc0b1a360
Autor:
H. J. Boele, C. Jung, S. Sherry, L. E. M. Roggeveen, S. Dijkhuizen, J. Öhman, E. Abraham, A. Uvarov, C. P. Boele, K. Gultig, A. Rasmussen, M. F. Vinueza-Veloz, J. F. Medina, S. K. E. Koekkoek, C. I. De Zeeuw, S. S. -H. Wang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Tests of human brain circuit function typically require fixed equipment in lab environments. We have developed a smartphone-based platform for neurometric testing. This platform, which uses AI models like computer vision, is optimized for at
Externí odkaz:
https://doaj.org/article/40dede7f6bf94e7b859a9f9bbf7e8c87
Autor:
M. J. Ottenhoff, S. Dijkhuizen, A. C. H. Ypelaar, N. L. de Oude, S. K. E. Koekkoek, S. S.-H. Wang, C. I. De Zeeuw, Y. Elgersma, H. J. Boele
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Individuals with Neurofibromatosis type 1 (NF1) experience a high degree of motor problems. The cerebellum plays a pivotal role in motor functioning and the NF1 gene is highly expressed in cerebellar Purkinje cells. However, it is not well u
Externí odkaz:
https://doaj.org/article/1a841e4e5a764d5f8bab376df6b14d57
Autor:
M. J. Ottenhoff, S. Dijkhuizen, A. C. H. Ypelaar, N. L. Oude, S. K. E. Koekkoek, S. S. -H. Wang, C. I. Zeeuw, Y. Elgersma, H. J. Boele
Individuals with Neurofibromatosis type 1 (NF1) experience a high degree of motor problems. The cerebellum plays a pivotal role in motor functioning and the NF1 gene is highly expressed in cerebellar Purkinje cells. However, it is not well understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12894d56d71301b8b431b852e672aa79
https://doi.org/10.21203/rs.3.rs-1758812/v1
https://doi.org/10.21203/rs.3.rs-1758812/v1
Publikováno v:
eNeuro, 9(2):ENEURO.0400-21.2022. Society for Neuroscience
eNeuro, 9:0400.21.2022. Society for Neuroscience
eNeuro, 9:0400.21.2022. Society for Neuroscience
Here we investigate stimulus generalization in a cerebellar learning paradigm, called eyeblink conditioning. Mice were conditioned to close their eyes in response to a 10 kHz tone by repeatedly pairing this tone with an air puff to the eye 250 ms aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc99ac7394e04e89adb78f4beea081f2
https://pure.eur.nl/en/publications/c82de3c5-f204-4112-ae2e-572e32b91926
https://pure.eur.nl/en/publications/c82de3c5-f204-4112-ae2e-572e32b91926
Autor:
Thomas A Van Essen, Ruben S Van Der Giessen, S K E Koekkoek, Frans van der Werf, Chris I De Zeeuw, Perry J J Van Genderen, David Overbosch, Marcel T G De Jeu
Publikováno v:
Frontiers in Neuroscience, Vol 4 (2010)
Mefloquine (a marketed anti-malaria drug) prophylaxis has a high risk of causing adverse events. Interestingly, animal studies have shown that mefloquine imposes a major deficit in motor learning skills by affecting the connexin 36 gap junctions of t
Externí odkaz:
https://doaj.org/article/d723623797e942a68028baa729300a3f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 3 (2010)
Over the past decade the advent of mouse transgenics has generated new perspectives on the study of cerebellar molecular mechanisms that are essential for eyeblink conditioning. However, it also appears that results from eyeblink conditioning experim
Externí odkaz:
https://doaj.org/article/3c7bf15ed6524fe29cb6ccc11d93cf67