Výsledky vyhledávání - "S. K. Calderwood"

Members of the 70-kilodalton heat shock protein family contain a highly conserved calmodulin-binding domain

Publikováno v: Molecular and Cellular Biology. 10:1234-1238

The 70-kilodalton heat shock protein (hsp70) family members appear to be essential components in a number cellular protein-protein interactions. We report here on the characterization of a new functional region in hsp70, a calmodulin-binding site. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6223625b5e0fdbc2edc0239e0e16a5f
https://doi.org/10.1128/mcb.10.3.1234

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Gap-junctional communication between feeder cells and recipient normal epithelial cells correlates with growth stimulation

Autor: U K, Ehmann, S K, Calderwood, M A, Stevenson

Publikováno v: In vitro cellulardevelopmental biology. Animal. 37(2)

LA7 rat mammary tumor cells stimulate the proliferation, in culture, of three normal epithelial cell types, namely mouse mammary, rat mammary, and mouse thymic cells. Gap-junctional communication between LA7 feeders and mouse mammary cells was demons

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https://pubmed.ncbi.nlm.nih.gov/11332735

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Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen

Autor: S T, Palayoor, M Y, Youmell, S K, Calderwood, C N, Coleman, B D, Price

Publikováno v: Oncogene. 18(51)

Apoptotic pathways controlled by the Rel/NF-kappaB family of transcription factors may regulate the response of cells to DNA damage. Here, we have examined the NF-kappaB status of several prostate tumor cell lines. In the androgen-independent prostat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf08080207f2989370e3ef76a62c7c69
https://pubmed.ncbi.nlm.nih.gov/10602496

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Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes

Autor: M A, Stevenson, M J, Zhao, A, Asea, C N, Coleman, S K, Calderwood

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(10)

Sodium salicylate (NaSal) and other nonsteroidal anti-inflammatory drugs (NSAIDs) coordinately inhibit the activity of NF-kappa B, activate heat shock transcription factor 1 and suppress cytokine gene expression in activated monocytes and macrophages

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23bef4ca333315b879183f2220d4d258
https://pubmed.ncbi.nlm.nih.gov/10553090

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Combined antitumor effect of radiation and ibuprofen in human prostate carcinoma cells

Autor: S T, Palayoor, E A, Bump, S K, Calderwood, S, Bartol, C N, Coleman

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(3)

Recent clinical observations indicate that ibuprofen may alleviate the radiation-induced dysuria that almost invariably occurs during radiation therapy for prostate cancer. Because the use of ibuprofen could consequently become common during radiatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0b6686df79d48277cfa4ef279178be0
https://pubmed.ncbi.nlm.nih.gov/9533546

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Potential role of heat shock transcription factor in the expression of inflammatory cytokines

Autor: C M, Cahill, H S, Lin, B D, Price, J L, Bruce, S K, Calderwood

Publikováno v: Advances in experimental medicine and biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b0a16266fdc5800e909e75e8dc4d84d
https://pubmed.ncbi.nlm.nih.gov/9547613

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Transcriptional repression of the prointerleukin 1beta gene by heat shock factor 1

Autor: C M, Cahill, W R, Waterman, Y, Xie, P E, Auron, S K, Calderwood

Publikováno v: The Journal of biological chemistry. 271(40)

Heat shock factor 1 activates the promoters of heat shock genes at elevated temperatures through its interaction with heat shock elements. We have examined a new role for heat shock factor 1 in the repression of the prointerleukin 1beta gene in human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e09e33c475d32a7ea683a2503b1b8f9
https://pubmed.ncbi.nlm.nih.gov/8926278

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X-irradiation, phorbol esters, and H2O2 stimulate mitogen-activated protein kinase activity in NIH-3T3 cells through the formation of reactive oxygen intermediates

Autor: M A, Stevenson, S S, Pollock, C N, Coleman, S K, Calderwood

Publikováno v: Cancer research. 54(1)

Extracellular signal-regulated kinases (ERKs), also known as mitogen-activated protein (MAP) kinases, are rapidly phosphorylated and activated in response to a number of external factors which promote growth and differentiation (T. G. Boulton, S. H.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::516a0daf4295b5da5b63bb20f9ffa5ec
https://pubmed.ncbi.nlm.nih.gov/8261431

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Increased sequence-specific p53-DNA binding activity after DNA damage is attenuated by phorbol esters

Autor: B D, Price, S K, Calderwood

Publikováno v: Oncogene. 8(11)

Damage to cellular DNA greatly increases the levels of the tumor-suppressor gene p53 and induces cell cycle arrest in G1. A critical function of wild-type p53 is its ability to bind to specific DNA sequences. The effect of DNA damage on the sequence-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae13731e346f4f21e4ab491e89eac315
https://pubmed.ncbi.nlm.nih.gov/8414506

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