Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S. Joseph Leibovich"'
Autor:
Pal Pacher, György Haskó, Endre Kókai, Balázs Koscsó, Balázs Csóka, László Virág, Zoltan H. Nemeth, S. Joseph Leibovich
Publikováno v:
Journal of Leukocyte Biology. 94:1309-1315
The alternatively activated macrophage phenotype induced by IL-10 is called M2c. Adenosine is an endogenous purine nucleoside that accumulates in the extracellular space in response to metabolic disturbances, hypoxia, inflammation, physical damage, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c44c31e18367293d2f38e53b02983a
https://doi.org/10.1189/jlb.0113043
https://doi.org/10.1189/jlb.0113043
Autor:
György Haskó, Michael R. Blackburn, Pal Pacher, E. Sylvester Vizi, Edwin A. Deitch, Balázs Csóka, Pál Gergely, Chun Xiao Sun, Zoltán Németh, S. Joseph Leibovich, László Virág
Publikováno v:
Blood. 110:2685-2695
We recently showed that A(2A) adenosine receptor activation by endogenous adenosine contributes to interleukin-10 (IL-10) production in polymicrobial sepsis. Here we investigated the molecular mechanisms underpinning this interaction between adenosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b540342b9e46f12179c45d631c64882
https://doi.org/10.1182/blood-2007-01-065870
https://doi.org/10.1182/blood-2007-01-065870
Autor:
Carol S. Lutz, Pal Pacher, S. Joseph Leibovich, Edwin A. Deitch, György Haskó, William C. Gause, Balázs Csóka, E. Sylvester Vizi, Zoltán Németh, Masahide Tone
Publikováno v:
The Journal of Immunology. 175:8260-8270
Adenosine receptor ligands have anti-inflammatory effects and modulate immune responses by up-regulating IL-10 production by immunostimulated macrophages. The adenosine receptor family comprises G protein-coupled heptahelical transmembrane receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6333f1db718da7093d86f37cfc0f2965
https://doi.org/10.4049/jimmunol.175.12.8260
https://doi.org/10.4049/jimmunol.175.12.8260
Autor:
E. Sylvester Vizi, S. Joseph Leibovich, László Virág, Edwin A. Deitch, Csaba Szabó, Beáta Sperlágh, Zoltán Németh, György Haskó
Publikováno v:
Biochemical and Biophysical Research Communications. 312:883-888
Adenosine is an endogenously released autocoid that has potent receptor-mediated modulatory effects on macrophage function. The intracellular pathways mediating these effects are incompletely understood. Since adenosine receptor occupancy has been as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0a2ff8d254f581196f4d8106de5bea
https://doi.org/10.1016/j.bbrc.2003.11.006
https://doi.org/10.1016/j.bbrc.2003.11.006
Autor:
Geert-Jan Boons, György Haskó, Madhuri Ramanathan, Grace Pinhal-Enfield, S. Joseph Leibovich, Stefanie N. Vogel, Andrew L. Salzman
Publikováno v:
The American Journal of Pathology. 163:711-721
Adenosine A(2A) receptor (A(2A)R) agonists synergize with Escherichia coli (E. coli) LPS [toll-like receptor (TLR)4 agonist] to up-regulate vascular endothelial growth factor (VEGF) expression in murine macrophages. Here, we demonstrate that TLR2, TL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cd974029e09514e17e2fbb743000d3
https://doi.org/10.1016/s0002-9440(10)63698-x
https://doi.org/10.1016/s0002-9440(10)63698-x
Autor:
Kristyn S. Masters, S. Joseph Leibovich, Paula Belem, Laura A. Poole-Warren, Jennifer L. West
Publikováno v:
Wound Repair and Regeneration. 10:286-294
Healing of chronic wounds such as diabetic foot ulcers is a significant clinical problem. Methods of accelerating healing in these difficult lower extremity sites include use of growth factor-loaded gels, hyperbaric oxygen, grafts, and artificial ski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a722922260575380405aefa7a80c62d
https://doi.org/10.1046/j.1524-475x.2002.10503.x
https://doi.org/10.1046/j.1524-475x.2002.10503.x
Autor:
Sidney M. Morris, Balázs Koscsó, Balázs Csóka, Zoltán Németh, Zsolt Selmeczy, S. Joseph Leibovich, Diane Kepka-Lenhart, William C. Gause, György Haskó, Peter J. Murray, Pal Pacher
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(1)
Adenosine has been implicated in suppressing the proinflammatory responses of classically activated macrophages induced by Th1 cytokines. Alternative macrophage activation is induced by the Th2 cytokines interleukin (IL)-4 and IL-13; however, the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba16e71379851281e8edf1d9c88c776a
https://pubmed.ncbi.nlm.nih.gov/21926236
https://pubmed.ncbi.nlm.nih.gov/21926236
Publikováno v:
Scopus-Elsevier
Vascular endothelial growth factor (VEGF) expression in murine peritoneal macrophages is strongly upregulated by hypoxia via transcriptional and posttranscriptional mechanisms. Interferon-γ (IFN-γ) with Escherichia coll lipopolysaccharide (LPS) als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ff4916e5aecd0479502e95e02bae0c
https://pubmed.ncbi.nlm.nih.gov/12773701
https://pubmed.ncbi.nlm.nih.gov/12773701
Autor:
S. Joseph Leibovich, György Haskó, Edwin A. Deitch, E. Sylvester Vizi, Csaba Szabó, Zoltán Németh
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 306(3)
Adenosine is released into the extracellular space from nerve terminals and cells subjected to ischemic stress. This nucleoside modulates a plethora of cellular functions via occupancy of specific receptors. Adenosine is also an important endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24def8eafda526120b6454104d59ff0e
https://pubmed.ncbi.nlm.nih.gov/12766259
https://pubmed.ncbi.nlm.nih.gov/12766259
Autor:
Richard A. Ashmun, J. C. Burrows, Alisa E. Koch, A. Thomas Look, Peter H. Domer, S. Joseph Leibovich
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology. 60(2)
We have selected several monoclonal antibodies (mAbs) producing using human rheumatoid arthritis (RA) synovial macrophages (m phi s) as immunogen. Of these, mAbs 8H2, 10G7 and 10G9 showed cross reactivity with endothelium, suggesting common antigens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef1684da8cd2a78667357932bdc09b2
https://pubmed.ncbi.nlm.nih.gov/1571092
https://pubmed.ncbi.nlm.nih.gov/1571092