Zobrazeno 1 - 10
of 17
pro vyhledávání: '"S. Jane Darnton"'
Autor:
Paula Chaves, S. Jane Darnton, Herman van Dekken, David G. Beer, David S. Schrump, Winand N.M. Dinjens, Hugo W. Tilanus, Laura H. Tang, Lin Lin, David S. Klimstra, A Dias Pereira, James R. Eshleman, Ronald van Marion, Catarina Ribeiro, Nasser K. Altorki, Jurjen J. Boonstra, Yutaka Shimada, Lúcia Roque, Hector A Alvarez
Publikováno v:
Journal of the National Cancer Institute, 102(4), 271-274. Oxford University Press
For decades, hundreds of different human tumor type-specific cell lines have been used in experimental cancer research as models for their respective tumors. The veracity of experimental results for a specific tumor type relies on the correct derivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ef8ad246db41df8ca291d04dea27ef
https://hdl.handle.net/1765/27491
https://hdl.handle.net/1765/27491
Autor:
Alan G. Casson, S. Jane Darnton, Christopher P. Wild, Anita Chauhan, Yvonne L. Wallis, Pierre Hainaut, Laura J. Hardie
Publikováno v:
Cancer Letters. 217:221-230
Alteration of the p16 tumor suppressor gene has been implicated as a critical lesion in the molecular pathogenesis of esophageal adenocarcinoma. The aim of this study was to characterize the spectrum of p16 alterations in surgically resected esophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe963c4c62bf184132208429a18e2e7a
https://doi.org/10.1016/j.canlet.2004.06.025
https://doi.org/10.1016/j.canlet.2004.06.025
Autor:
Christopher C. McConkey, Christopher W. Dawson, Chris Tselepis, S. Jane Darnton, Rob C Stuart, Rebecca Harrison, Nicholas A. Wright, Janusz Jankowski, Robert G. Hardy, Ian Perry
Publikováno v:
Oncogene. 21:6071-6081
Barrett's metaplasia (BM) is an early lesion in the progression from oesophageal inflammation through dysplasia to the development of Barrett's adenocarcinoma (BA). Previous work indicates that BM and BA are associated with reduced E-cadherin express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcffa44e49149e2efa0dec3e38ba7e5b
https://doi.org/10.1038/sj.onc.1205731
https://doi.org/10.1038/sj.onc.1205731
Autor:
Hazel K. Williams, Isobel Hanson, Rachael Bruton, Janusz Jankowski, Alan G. Casson, D. Scott A. Sanders, S. Jane Darnton
Publikováno v:
International Journal of Cancer. 79:573-579
Maintenance of an adhesive function for cadherins requires appropriate membranous cellular expression and intact cadherin-catenin complexes. In normal squamous mucosa of the oesophagus there is membranous co-expression of E- and P-cadherin (E-cad, P-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48bafae6567fabfe55045915e1b9ce1
https://doi.org/10.1002/(sici)1097-0215(19981218)79:6<573::aid-ijc4>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19981218)79:6<573::aid-ijc4>3.0.co
Autor:
Rebecca Harrison, S. Jane Darnton, Moray J. Campbell, Mark R. Anderson, Paul A. Atherfold, Janusz Jankowski, Jolanta Obszynska
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(20 Pt 1)
Purpose: The incidence of esophageal adenocarcinoma is rising, and survival rates remain poor. The hepatocyte growth factor (HGF) receptor Met has been detected in esophageal cancer. The perturbation of cadherin/catenin complexes has also been shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1074db55c9404275fb189a0ec671bb3
https://pubmed.ncbi.nlm.nih.gov/17062664
https://pubmed.ncbi.nlm.nih.gov/17062664
Publikováno v:
International journal of cancer. 115(3)
Amongst involvement in diverse physiological and pathological processes, TIMP-3 may have an important role in tumour development, growth and metastasis by interaction with metalloproteases in the extracellular matrix. We studied the role and prognost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e4fb06ccc7b345ed919652b4913e29
https://pubmed.ncbi.nlm.nih.gov/15688381
https://pubmed.ncbi.nlm.nih.gov/15688381
Publikováno v:
Cancer Chemotherapy and Pharmacology. 37:496-498
We evaluated the effect of brief neoadjuvant chemotherapy in patients with apparently operable adenocarcinoma of the oesophagus. Two courses of mitomycin (6 mg/m2), ifosfamide (3 g/m2) and cisplatin (50 mg/m2; MIC) were given followed by evaluation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dfd7d686a2db7555a0bd8882d70ecd
https://doi.org/10.1007/s002800050418
https://doi.org/10.1007/s002800050418
Autor:
J. Gerdes, M. H. G. Becker, G. Key, G. Cattoretti, Harry W. Sanders, Adrian G. Smith, John Crocker, S. Jane Darnton, Michael R. Gray
Publikováno v:
The Journal of Pathology. 168:85-87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124de9644ecc5b2a6f8ffa409316c94a
https://doi.org/10.1002/path.1711680114
https://doi.org/10.1002/path.1711680114
Publikováno v:
The Annals of thoracic surgery. 69(1)
Background . Whereas a proximal resection margin of 12 cm is recommended for complete resection of esophageal cancer, the extent of distal resection is unclear. Methods . We examined distal resection margins in a consecutive series of patients who un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f363f25d328d3eb2d7b6dcbe256734
https://pubmed.ncbi.nlm.nih.gov/10654514
https://pubmed.ncbi.nlm.nih.gov/10654514
Autor:
Alan G. Casson, S. Jane Darnton, Venice Archer, David Ferry, Deborah Stocken, Paul Mulholland
Publikováno v:
Journal of Clinical Oncology. 22:2513-2514
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f355cfeb5302d6644b4684a8a21033df
https://doi.org/10.1200/jco.2004.99.054
https://doi.org/10.1200/jco.2004.99.054