Zobrazeno 1 - 10
of 23
pro vyhledávání: '"S. Jack Lin"'
Autor:
Richard Austin, Sony Rocha, Kathryn Kwant, Maria Dayao, Wade Aaron, Evan Callihan, Golzar Hemmati, Kevin Wright, Yinghua Xiao, Timothy Yu, Jessica O’Rear, Stephen Yu, Avneel Hundal, Bryan Lemon, Holger Wesche, Katrina Stephenson, Subramanian Thothathri, Rose Banzon, Eric Bragg, Willis Kwong, Hubert Situ, Taggra Jackson, Linh To, S Jack Lin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/312e28f04efa43879714a1ce7e252c2a
Autor:
Daniel Kirchhofer, Amitabha Chaudhuri, Robert A. Lazarus, Thomas D. Wu, Lydia Santell, Ming-Hong Xie, S. Jack Lin, Ganesh A. Kolumam, Rajkumar Ganesan
Macrophage-stimulating protein (MSP) is a plasminogen-related growth factor and ligand for the receptor tyrosine kinase RON. The MSP/RON system promotes wound healing and invasive tumor growth and suppresses proinflammatory immune response. MSP bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab92bcdb36a8748185ea7692af62458f
https://doi.org/10.1158/1541-7786.c.6542076
https://doi.org/10.1158/1541-7786.c.6542076
Autor:
Daniel Kirchhofer, Amitabha Chaudhuri, Robert A. Lazarus, Thomas D. Wu, Lydia Santell, Ming-Hong Xie, S. Jack Lin, Ganesh A. Kolumam, Rajkumar Ganesan
PDF file - 504K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25cea70a42c7644cf880ccb27c359620
https://doi.org/10.1158/1541-7786.22518687.v1
https://doi.org/10.1158/1541-7786.22518687.v1
Autor:
Laura B. Valenzuela, Chi-Heng Wu, Wade Aaron, Raphalea R. Banzon, Mabel Bush, S. Jack Lin, Sony S. Rocha, Subramanian Thothathri, Holger Wesche, Mary Ellen Molloy, Banmeet S. Anand
Publikováno v:
Cancer Research. 83:5070-5070
TriTAC® is a T cell engager platform comprised of three binding domains: a target binder for tumor cell engagement, an albumin binder for half-life extension, and a CD3 binder for T cell engagement. HPN328 is a Delta-like ligand 3 (DLL3)-targeting T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0105608c031459aafbf4ca3c05c93279
https://doi.org/10.1158/1538-7445.am2023-5070
https://doi.org/10.1158/1538-7445.am2023-5070
Autor:
Regina J. Lin, Sony S. Rocha, Maria R. Dayao, Subramanian Thothathri, Raphaela Rose Banzon, Kevin J. Wright, Wade Aaron, Yinghua Xiao, Nick Bergo, Linh To, Mabel Bush, Manasi Barath, Yi Yang, Timothy Yu, Willis Kwong, Hubert Situ, Eric Bragg, Jessica O'Rear, Kevin Carlin, Stephen Yu, Maritza Solorio, Bryan Lemon, Richard Austin, Holger Wesche, S. Jack Lin
Publikováno v:
Cancer Research. 83:2927-2927
Integrin-β6 (ITGB6) is a transmembrane protein that partners exclusively with the integrin-αV subunit to form the integrin-αVβ6 heterodimer. Due to its roles in tissue remodeling and cancer pathogenesis, therapeutic targeting of integrin-αVβ6 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a9d00c7377764d7ed0f8c808962355c
https://doi.org/10.1158/1538-7445.am2023-2927
https://doi.org/10.1158/1538-7445.am2023-2927
Autor:
Sony S. Rocha, Regina Lin, Maria R. Dayao, Raphaela Rose Banzon, Subramanian Thothathri, Kevin J. Wright, Wade Aaron, Yinghua Xiao, Nick Bergo, Linh To, Mabel Bush, Manasi Barath, Timothy Yu, Willis Kwong, Hubert Situ, Eric Bragg, Jessica O'Rear, Kevin Carlin, Stephen Yu, Maritza Solorio, Bryan Lemon, Richard Austin, Holger Wesche, S. Jack Lin
Publikováno v:
Cancer Research. 83:2928-2928
Tumor-associated calcium signal transducer 2 (Trop2) is a cell surface glycoprotein that promotes cell renewal, proliferation and tumorigenesis. Trop2 is homogenously overexpressed in numerous solid tumor types, including breast, head and neck, prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a627f4564e09b6e1e4c7b31e14f37db1
https://doi.org/10.1158/1538-7445.am2023-2928
https://doi.org/10.1158/1538-7445.am2023-2928
Autor:
Paulina Kasperkiewicz, Marcin Poreba, Scott J Snipas, S Jack Lin, Daniel Kirchhofer, Guy S Salvesen, Marcin Drag
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132818 (2015)
Human neutrophil serine protease 4 (NSP4), also known as PRSS57, is a recently discovered fourth member of the neutrophil serine proteases family. Although its biological function is not precisely defined, it is suggested to regulate neutrophil respo
Externí odkaz:
https://doaj.org/article/9a6893e6b5384d4eb3d6fddaa651dc61
Autor:
Andrew P. AhYoung, Stefan Gerhardy, Menno van Lookeren Campagne, Daniel Kirchhofer, S. Jack Lin
Publikováno v:
Biochimie. 166:19-26
The recently discovered neutrophil serine protease 4 (NSP4) is the fourth member of the NSP family, which includes the well-studied neutrophil elastase, proteinase 3 and cathepsin G. Like the other three NSP members, NSP4 is synthesized by myeloid pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0c9fc30800dc52a110981a1d568784
https://doi.org/10.1016/j.biochi.2019.03.020
https://doi.org/10.1016/j.biochi.2019.03.020
Autor:
Kathryn Strobel Kwant, Sony S. Rocha, Timothy Yu, Katrina Stephenson, Raphaela Rose Banzon, Sydney Vollhardt, Golzar Hemmati, Evan Callihan, Wade H. Aaron, Subramanian Thothathri, Jessica O'Rear, Eric Bragg, Willis Kwong, Hubert Situ, Avneel Hundal, Stephen Yu, Taggra Jackson, Kevin Carlin, Yinghua Xiao, Maria Rosalyn Dayao, Linh To, Nick Bergo, Kevin Wright, Richard Austin, Holger Wesche, Bryan Lemon, S. Jack Lin
Publikováno v:
Cancer Research. 82:2861-2861
CD3-targeted T cell engagers are potent anti-tumor therapies, but their development often requires management of cytokine release syndrome (CRS). One strategy to reduce CRS is subcutaneous dosing, which is hypothesized to mitigate CRS by reducing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f688ce9d413f959d61e29475d25a2de
https://doi.org/10.1158/1538-7445.am2022-2861
https://doi.org/10.1158/1538-7445.am2022-2861
Autor:
Wouter L W Hazenbos, Kimberly K Kajihara, Richard Vandlen, J Hiroshi Morisaki, Sophie M Lehar, Mark J Kwakkenbos, Tim Beaumont, Arjen Q Bakker, Qui Phung, Lee R Swem, Satish Ramakrishnan, Janice Kim, Min Xu, Ishita M Shah, Binh An Diep, Tao Sai, Andrew Sebrell, Yana Khalfin, Angela Oh, Chris Koth, S Jack Lin, Byoung-Chul Lee, Magnus Strandh, Klaus Koefoed, Peter S Andersen, Hergen Spits, Eric J Brown, Man-Wah Tan, Sanjeev Mariathasan
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003653 (2013)
Infection of host tissues by Staphylococcus aureus and S. epidermidis requires an unusual family of staphylococcal adhesive proteins that contain long stretches of serine-aspartate dipeptide-repeats (SDR). The prototype member of this family is clump
Externí odkaz:
https://doaj.org/article/9ab686e914474260984f11e6595e12d4