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pro vyhledávání: '"S. J. Zullo"'
Autor:
C R Merril, M Chloupkova, S J Zullo, W A Fenton, J M Eisenstadt, W T Parks, Baoxian Wei, Henry Weiner
Publikováno v:
Rejuvenation Research. 8:18-28
Point and deletion mutations and a general depletion of mammalian mitochondrial DNA (mtDNA) give rise to a wide variety of medical syndromes that are refractory to treatment, possibly including aging itself. While gene therapy directed at correcting
Publikováno v:
DNA and cell biology. 19(10)
We have sequenced a genomic clone of the gene encoding the mouse mitochondrial DNA polymerase. The gene consists of 23 exons, which span approximately 13.2 kb, with exons ranging in size from 53 to 768 bp. All intron-exon boundaries conform to the GT
Publikováno v:
Cytogenetics and cell genetics. 78(3-4)
Cloned cDNAs for the human mitochondrial DNA polymerase gamma (POLG) were identified by homology with the yeast mitochondrial DNA polymerase catalytic subunit (MIP). Fluorescence in situ hybridization (FISH) of human and mouse bacterial artificial ch