Výsledky vyhledávání - "S. J. W. Allen"

Inhibition of HIV-1 RNase H Activity by Nucleotide Dimers and Monomers

Autor: S. H. Krawczyk, J. M. Cherrington, N. Bischofberger, S. J. W. Allen, A. S. Mulato, L. R. McGee

Publikováno v: Antiviral Chemistry and Chemotherapy. 7:37-45

Nucleotide dimers and monomers were shown to inhibit human immunodeficiency virus type 1 (HIV) RNase H activity. Several effective inhibitors were identified and placed into three general groups based on biochemical characterization of their inhibiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25f9e690fd1d0b02b06e1a3f3ed532c8
https://doi.org/10.1177/095632029600700107

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Kinetic Interaction of the Diphosphates of 9-(2-phosphonylmethoxyethyl)adenine and Other anti-HIV Active Purine Congeners with HIV Reverse Transcriptase and Human DNA Polymerases α, β and γ

Autor: J. M. Cherrington, N. Bischofberger, S. J. W. Allen, Ming S. Chen

Publikováno v: Antiviral Chemistry and Chemotherapy. 6:217-221

The inhibitory effects of the diphosphates of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and its analogues on HIV reverse transcriptase and human DNA polymerases α, β, and γ have been studied. The analogues investigated are the diphosphates of 9-(

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::084ce8fdb0311d172884dcf8d78cdb17
https://doi.org/10.1177/095632029500600403

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