Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S. J. Spengler"'
Autor:
S J, Spengler
Publikováno v:
Science (New York, N.Y.). 287(5456)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2574d090535886d103bcb322c1008f93
https://pubmed.ncbi.nlm.nih.gov/10712158
https://pubmed.ncbi.nlm.nih.gov/10712158
Publikováno v:
Biochemistry. 28:1478-1483
The effect of alkyl group size on ability to act as deoxythymidine triphosphate (dTTP) has been studied for the carcinogen products O2-methyl-, O2-ethyl-, and O2-isopropyl-dTTP by using three types of nucleic acids as template and DNA polymerase I (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1764eabdce3324a451ab9f7c16a843b3
https://doi.org/10.1021/bi00430a008
https://doi.org/10.1021/bi00430a008
Publikováno v:
Proceedings of the National Academy of Sciences. 83:28-32
In a previous paper, we reported that O4-methyl dTTP can be incorporated into poly(dA-dT) in place of thymidine without distortion of the helical structure, but on replication it could behave as deoxycytidine and misincorporate dGTP. Only weak intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1197d285049af8eb440750a5fc7ed4
https://doi.org/10.1073/pnas.83.1.28
https://doi.org/10.1073/pnas.83.1.28
Publikováno v:
Biochemistry. 25:1201-1205
O4-Methyl-, O4-ethyl-, and O4-isopropylthymidine 5'-triphosphates, which can be formed by N-nitroso carcinogens, were tested for their ability to substitute for thymidine 5'-triphosphate (dTTP) in synthesis catalyzed by Escherichia coli DNA polymeras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb884e3e55286f2943cd9c1bab74c249
https://doi.org/10.1021/bi00354a001
https://doi.org/10.1021/bi00354a001
Publikováno v:
The Journal of Organic Chemistry. 52:2374-2378
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d72e9e56aa9b33e0d20f20695e2052a
https://doi.org/10.1021/jo00388a007
https://doi.org/10.1021/jo00388a007
Publikováno v:
The Journal of biological chemistry. 249(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52db382ddbede9fa9445ba80284a2432
https://pubmed.ncbi.nlm.nih.gov/4592259
https://pubmed.ncbi.nlm.nih.gov/4592259
Publikováno v:
ChemInform. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c98288e36828db1a0fff5ea2526c9c
https://doi.org/10.1002/chin.198749338
https://doi.org/10.1002/chin.198749338
Autor:
S J, Spengler, B, Singer
Publikováno v:
Cancer research. 48(17)
Chloroacetaldehyde, the stable metabolite of the human carcinogen vinyl chloride, forms interstrand cross-links in vitro in salmon sperm DNA and in the alternating copolymer, poly(deoxyadenylate-deoxythymidylate) [poly(dA-dT)]. Formation of the cross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf046ca21fa7ac90b4d3083b9ec97b1e
https://pubmed.ncbi.nlm.nih.gov/3409221
https://pubmed.ncbi.nlm.nih.gov/3409221
Publikováno v:
IARC scientific publications. (84)
The O2- and O4-methyldeoxythymidine triphosphates (O-alkyl dTTP) can be used to substitute for dTTP in Escherichia coli DNA polymerase I (Pol I)-catalysed synthesis of poly[deoxyadenosine-deoxythymidine] (dA-dT). When incorporated into the polynucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a619874cf5c6bf14b40118c5eb0ab2e
https://pubmed.ncbi.nlm.nih.gov/3315998
https://pubmed.ncbi.nlm.nih.gov/3315998