Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S. J. Pratt"'
Autor:
H E Witkowska, Alison Brownlie, Carlo Brugnara, Andrew C. Oates, S J Pratt, Adriana Donovan, Barry H. Paw, Shigeru Sassa, Leonard I. Zon
Publikováno v:
Nature Genetics. 20:244-250
Many human anaemias are caused by defects in haemoglobin synthesis. The zebrafish mutant sauternes (sau) has a microcytic, hypochromic anaemia, suggesting that haemoglobin production is perturbed. During embryogenesis, sau mutants have delayed erythr
Publikováno v:
ChemInform. 22
Autor:
A C, Oates, A, Brownlie, S J, Pratt, D V, Irvine, E C, Liao, B H, Paw, K J, Dorian, S L, Johnson, J H, Postlethwait, L I, Zon, A F, Wilks
Publikováno v:
Blood. 94(8)
Members of the JAK family of protein tyrosine kinase (PTK) proteins are required for the transmission of signals from a variety of cell surface receptors, particularly those of the cytokine receptor family. JAK function has been implicated in hematop
Autor:
A C, Oates, P, Wollberg, S J, Pratt, B H, Paw, S L, Johnson, R K, Ho, J H, Postlethwait, L I, Zon, A F, Wilks
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 215(4)
Transcription factors of the STAT family are required for cellular responses to multiple signaling molecules. After ligand binding-induced activation of cognate receptors, STAT proteins are phosphorylated, hetero- or homodimerize, and translocate to
Autor:
K H, Lee, J J, Marden, M S, Thompson, H, MacLennan, Y, Kishimoto, S J, Pratt, S, Schulte-Merker, M, Hammerschmidt, S L, Johnson, J H, Postlethwaite, D C, Beier, L I, Zon
Publikováno v:
Developmental genetics. 23(2)
The BMP family of polypeptide growth factors has been shown to play diverse roles in establishing embryonic patterning and tissue fates. We report the cloning of the zebrafish homologue of BMP-2, examine its expression during embryogenesis, and find
Publikováno v:
Australian Journal of Chemistry. 43:2107
A total synthesis of pannaric acid 6-methyl ester (3,9-dihydroxy-6-methoxycarbonyl-1,7-dimethyldibenzofuran-2-carboxylic acid) (2) has been achieved by a biomimetic -type approach with palladium(II) acetate in the key cyclization step. This acid (2)
Autor:
S. J. Pratt
Publikováno v:
ACM SIGOPS Operating Systems Review. 21:23-32
Autor:
S. J. Pratt
Publikováno v:
IEEE Transactions on Engineering Management. :116-123
Distributed processing configurations have a distinct advantage over a centralized approach in their adaptability to a constantly changing environment. There are many other desirable attributes of distributed processing, including enhanced survivabil
Autor:
S. J. Pratt
Publikováno v:
ACM SIGOPS Operating Systems Review. 20:25-37
The performance of any computing system is seriously affected by the performance of the resident operating system. Distributed computing systems are no different. There have been many successful attempts at harnessing the full potential offered by di
Autor:
S. J. Pratt
Publikováno v:
Microprocessing and Microprogramming. 23:291-297
In addition to providing raw computer power a distributed processing environment is amenable to incremented design. This inherent design feature means that it is possible to augment existing facilities by ‘simply’ interfacing new resources as and