Zobrazeno 1 - 10
of 15
pro vyhledávání: '"S. J. Lockett"'
Publikováno v:
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 17
Cell adhesion molecules (CAMs) are proteins which anchor cells to each other and to the extracellular matrix (ECM), but whose functions also include signal transduction, differentiation, and apoptosis. We are testing a hypothesis that particle radiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f6d19f963c2852f43ee710e10780ff0
https://pubmed.ncbi.nlm.nih.gov/11776988
https://pubmed.ncbi.nlm.nih.gov/11776988
Autor:
P, Nagy, L, Bene, M, Balázs, W C, Hyun, S J, Lockett, N Y, Chiang, F, Waldman, B G, Feuerstein, S, Damjanovich, J, Szöllosi
Publikováno v:
Cytometry. 32(2)
erbB2, a member of the epidermal growth factor (EGF) receptor-type tyrosine kinase receptor family, is overexpressed in breast carcinomas with poor prognosis. We examined the cell surface association of this receptor with itself and with other cell s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31cbde49ac1782739bcb32f9d33a4ffc
https://pubmed.ncbi.nlm.nih.gov/9627225
https://pubmed.ncbi.nlm.nih.gov/9627225
Publikováno v:
Cytometry. 31(4)
Segmentation of intact cell nuclei in three-dimensional (3D) images of thick tissue sections is an important basic capability necessary for many biological research studies. Because automatic algorithms do not correctly segment all nuclei in tissue s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::885e5c9b746c549317bf2b6b917fa21d
https://pubmed.ncbi.nlm.nih.gov/9551603
https://pubmed.ncbi.nlm.nih.gov/9551603
Publikováno v:
Cytometry. 23(4)
Techniques to identify low frequency (i.e., 10(-4)-10(-5)) tumor cells in bone marrow and peripheral blood of cancer patients provide opportunities for early detection of disseminated disease and characterization of the properties of cells released f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ade792695244e6301547c7c0e209407a
https://pubmed.ncbi.nlm.nih.gov/8900478
https://pubmed.ncbi.nlm.nih.gov/8900478
Publikováno v:
Oncogene. 8(10)
The loss of the tumor-suppressor activity of p53, either by mutation or by interaction with the human papillomavirus (HPV) E6 protein, is considered to be an important mechanism in the carcinogenesis of cervical cancer. We have studied the cytologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60273abff590d9b8b943641dd8c28bdd
https://pubmed.ncbi.nlm.nih.gov/8397367
https://pubmed.ncbi.nlm.nih.gov/8397367
Publikováno v:
Analytical and quantitative cytology and histology. 14(3)
Digital image-based cytometry of clinical specimens labeled with fluorescent, disease-specific markers holds promise for becoming an important diagnostic and prognostic technique because the technique can make a diverse range of quantitative biochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f605b0805a87557053c7a26c9bbf52a
https://pubmed.ncbi.nlm.nih.gov/1418268
https://pubmed.ncbi.nlm.nih.gov/1418268
Autor:
S J, Lockett, K, Jacobson, M, O'Rand, D G, Kaufman, M, Corcoran, M G, Simonsen, H, Taylor, B, Herman
Publikováno v:
BioTechniques. 10(4)
The combination of digitized microscopy, algorithms for object recognition and fluorescent labeling is a promising approach for reliable, quick, automated and cost-effective screening of clinical specimens. We describe two conceptually different algo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad938978ad4407dad5e2500c2a0ca61f
https://pubmed.ncbi.nlm.nih.gov/1867861
https://pubmed.ncbi.nlm.nih.gov/1867861
Publikováno v:
Analytical and quantitative cytology and histology. 13(1)
Digitized fluorescence microscopy in conjunction with automated image segmentation is a promising approach for screening clinical specimens quickly and reliably. This paper describes the hardware and software of a prototype image-based cytometer that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e9375afba25aa34f33b2aba8664e81f
https://pubmed.ncbi.nlm.nih.gov/2025371
https://pubmed.ncbi.nlm.nih.gov/2025371
Autor:
J E Bateman, J.R. Taylor, M.R. Hawkesworth, David B. Ramsden, Arthur R. Bradwell, S. Maudsley, S J Lockett, C A Hanham
Publikováno v:
Physics in Medicine and Biology. 31:535-542
We have assessed a multiwire camera for the high speed, quantitative autoradiography of tritium-labelled substances in two-dimensional systems. Exposure times for 3H were typically 1000 times less than film-based methods, with a detection efficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e91b726f43c3afc1c40fa730b4db65b
https://doi.org/10.1088/0031-9155/31/5/006
https://doi.org/10.1088/0031-9155/31/5/006
Publikováno v:
Physics in Medicine and Biology. 32:877-885
The authors have shown that tritium-labelled substances in two-dimensional systems can be quantitated using a multiwire camera. Its accuracy has now been improved by correcting results for non-uniformity of response over the detection area. Uniformit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef839f2830eeb493a4bec5b10db7b0c
https://doi.org/10.1088/0031-9155/32/7/007
https://doi.org/10.1088/0031-9155/32/7/007