Zobrazeno 1 - 10
of 20
pro vyhledávání: '"S. J. Kohlhepp"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:1065-1070
Dietary calcium supplements attenuate experimental aminoglycoside nephrotoxicity. In cultured renal tubular cells, intracellular calcium levels have been reported to rise with aminoglycoside addition to the culture medium. In experiments designed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d3349b7a4a71b2d8f0615455578890
https://doi.org/10.1128/aac.38.5.1065
https://doi.org/10.1128/aac.38.5.1065
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2678-2683
Scant data exist on intracellular events during aminoglycoside-induced postantibiotic effect (PAE). We examined DNA, RNA, and protein syntheses after tobramycin exposure using [3H]thymidine, [14C]uracil, and [14C]alanine incorporation in a clinical E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62290904cac850a75a7cee816a5b94c
https://doi.org/10.1128/aac.37.12.2678
https://doi.org/10.1128/aac.37.12.2678
Publikováno v:
Antimicrobial Agents and Chemotherapy. 35:2591-2595
Polyaspartic Acid (PAA) protects the kidney from experimental gentamicin nephrotoxicity despite large increases in renal cortical gentamicin content. In these experiments, prominent cytoplasmic vacuoles were noted in all animals that received PAA wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c25bd6c5feb41e53087ceb7fe9b1e5
https://doi.org/10.1128/aac.35.12.2591
https://doi.org/10.1128/aac.35.12.2591
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:2169-2171
The surface membrane properties of LLC-PK1 cells grown with and without various amounts of gentamicin or tobramycin for various lengths of time were determined by measuring the diffusion coefficient of N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)dipalmitoyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2437f7df2174043b0bfd25a1b7b203a4
https://doi.org/10.1128/aac.38.9.2169
https://doi.org/10.1128/aac.38.9.2169
Autor:
D N, Gilbert, S J, Kohlhepp, K A, Slama, G, Grunkemeier, G, Lewis, R J, Dworkin, S E, Slaughter, J E, Leggett
Publikováno v:
Antimicrobial agents and chemotherapy. 45(3)
The phenotypic resistance of selected organisms to ciprofloxacin, levofloxacin, and trovafloxacin was defined as a MIC ofor =4 microg/ml. The dynamics of resistance were studied after single and sequential drug exposures: clinical isolates of methici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06fa703c01553ee8e46d4a5a93a5b646
https://pubmed.ncbi.nlm.nih.gov/11181375
https://pubmed.ncbi.nlm.nih.gov/11181375
Autor:
P. W. Kohnen, S. J. Kohlhepp, David N. Gilbert, William M. Bennett, James E. Leggett, Suzanne K. Swan
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:2556-2558
It is known that daily polyaspartic acid (PAA) protects the kidney from gentamicin nephrotoxicity in a standardized rat model despite marked cortical accumulation of the aminoglycoside. The present experiments address the duration of PAA protection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5910fac5c6d0b12cd1c0836578960860
https://doi.org/10.1128/aac.36.11.2556
https://doi.org/10.1128/aac.36.11.2556
Publikováno v:
Antimicrobial agents and chemotherapy. 40(2)
The pharmacokinetics and tolerability of 1-g doses of ceftriaxone diluted in sterile water, 1% lidocaine, or buffered lidocaine were investigated. No difference in bioequivalence was noted between the three treatments. No difference in peak creatine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b21dba751bf29c049d8c57666f1999c
https://pubmed.ncbi.nlm.nih.gov/8834905
https://pubmed.ncbi.nlm.nih.gov/8834905
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(3)
The in vitro interaction of polyaspartic acid (PAA) with aminoglycosides was evaluated using double diffusion in agar, dialysis chambers and changes in the optical density of test solutions. The results document a reversible, presumably electrostatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93742a05644c73f299866c19fa3b85d3
https://pubmed.ncbi.nlm.nih.gov/1469645
https://pubmed.ncbi.nlm.nih.gov/1469645
Autor:
D, Kremer, M Y, Munar, S J, Kohlhepp, S K, Swan, E A, Stinnett, D N, Gilbert, E W, Young, W M, Bennett
Publikováno v:
Pharmacotherapy. 12(1)
A few reports in the literature describe zidovudine (AZT) pharmacokinetics in patients undergoing hemodialysis; however, the effect of continuous ambulatory peritoneal dialysis (CAPD) on the drug's disposition has not been studied. The pharmacokineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21719c541bec88456764ec79d913e45e
https://pubmed.ncbi.nlm.nih.gov/1549540
https://pubmed.ncbi.nlm.nih.gov/1549540
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:347-348
Polyaspartic acid (PAA) ameliorates experimental gentamicin nephrotoxicity despite marked accumulation of gentamicin in the renal cortex. The experiments described here probe the extent of PAA's nephroprotective action when increasing doses of gentam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d7a4d2c141af64a4f0ec75dbf89436
https://doi.org/10.1128/aac.37.2.347
https://doi.org/10.1128/aac.37.2.347