Zobrazeno 1 - 10
of 43
pro vyhledávání: '"S. J. Kennel"'
Autor:
S J, Kennel, T, Lankford, S, Davern, L, Foote, K, Taniguchi, I, Ohizumi, Y, Tsutsumi, S, Nakagawa, T, Mayumi, S, Mirzadeh
Publikováno v:
European journal of cancer (Oxford, England : 1990). 38(9)
In previous work, we have demonstrated that vascular targeting of [213Bi], an alpha-emitter, to lung blood vessels could efficiently destroy tumour colonies growing in the lung. In order to expand this approach to treatment of tumours growing in othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8efec5e45de40010ceac40dd910c0d1e
https://pubmed.ncbi.nlm.nih.gov/12044516
https://pubmed.ncbi.nlm.nih.gov/12044516
Publikováno v:
Journal of applied toxicology : JAT. 20(6)
Trinitrotoluene (TNT) and related compounds were tested for induction of mutation in the CHO-hprt mutation assay. The parent compound, TNT, was consistently found to be mutagenic at concentrations above 40 microg ml(-1), whether or not S9 activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba95dc2c878c90c980102ed283a53af1
https://pubmed.ncbi.nlm.nih.gov/11180265
https://pubmed.ncbi.nlm.nih.gov/11180265
Autor:
I A, Davis, S J, Kennel
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
A monoclonal antibody (201B) specific to murine thrombomodulin, covalently linked to cyclohexyl diethylenetriaminepentaacetic acid, successfully delivers chelated 213Bi, an alpha-particle emitter, (213Bi-201B) rapidly to lung vascular endothelium. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25aa8f73330f44c360418e0e10779dab
https://pubmed.ncbi.nlm.nih.gov/10541358
https://pubmed.ncbi.nlm.nih.gov/10541358
Autor:
S J, Kennel, M, Stabin, J C, Roeske, L J, Foote, P K, Lankford, M, Terzaghi-Howe, H, Patterson, J, Barkenbus, D M, Popp, R, Boll, S, Mirzadeh
Publikováno v:
Radiation research. 151(3)
Monoclonal antibody 13A to murine CD44 was used to bind the alpha-particle emitter 213Bi to cell surfaces of cultured EMT-6 or Line 1 tumor cells. Data on kinetics and saturation of binding, cell shape and nuclear size were used to calculate the abso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::879909c3f08b3f7775b5139c1d383c09
https://pubmed.ncbi.nlm.nih.gov/10073661
https://pubmed.ncbi.nlm.nih.gov/10073661
Publikováno v:
Experimental cell research. 210(1)
Structural and functional analyses of several integrin heterodimers were performed in non-small-cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cell lines. The expression of beta 1, beta 3, beta 4, and beta 5 heterodimers was evaluated at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4883bfc578a1f70e273c6f6ff19f2e9
https://pubmed.ncbi.nlm.nih.gov/7505746
https://pubmed.ncbi.nlm.nih.gov/7505746
Publikováno v:
Pharmaceutical research. 10(4)
Potential therapeutic applications of recently developed liposomes with a reduced affinity to the reticuloendothelial systems and a prolonged circulation time as targeting systems for lipophilic prodrugs were examined. In these studies, liposomes com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d91268240b20054448186a842a03761d
https://pubmed.ncbi.nlm.nih.gov/8483832
https://pubmed.ncbi.nlm.nih.gov/8483832
Autor:
R D, Blumenthal, R M, Sharkey, L, Haywood, A M, Natale, G Y, Wong, J A, Siegel, S J, Kennel, D M, Goldenberg
Publikováno v:
Cancer research. 52(21)
The therapeutic potential of radiolabeled antibodies is usually evaluated in experimental animal models bearing s.c. xenografts. We have established a micrometastatic model of the GW-39 human colonic carcinoma in the nude mouse lung (J. Natl. Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64905eb8e28708809d793ff90775c261
https://pubmed.ncbi.nlm.nih.gov/1394228
https://pubmed.ncbi.nlm.nih.gov/1394228
Publikováno v:
The Journal of biological chemistry. 267(8)
Previously, two rat monoclonal antibodies where developed which bind distinct epitopes on a murine glycoprotein, P112, which is expressed primarily in lung capillary endothelium. In this paper we show that P112 is identical to the endothelial anticoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2001e437aa941c2c6591970f67becb8
https://pubmed.ncbi.nlm.nih.gov/1372003
https://pubmed.ncbi.nlm.nih.gov/1372003
Autor:
S J, Kennel
Publikováno v:
Cancer research. 52(5)
Monoclonal antibody (MoAb) 11A and MoAb 13A recognize normal murine cell surface glycoproteins, which are also expressed in high concentrations on Line 1 lung carcinoma. Studies were initiated to examine the competition in vivo for radiolabeled MoAb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a16420f4d0a9e59d97bc099431a27e0
https://pubmed.ncbi.nlm.nih.gov/1737391
https://pubmed.ncbi.nlm.nih.gov/1737391
Publikováno v:
Cancer research. 51(5)
Detailed evaluations of the microdistribution of 125I-labeled monoclonal antibodies (MoAbs) to normal tissue antigens were conducted in BALB/c mice. MoAb 273-34A, which binds to a target molecule on the lumenal surface of lung endothelial cells, loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7a5293b80313dc8955e5e698bea357e
https://pubmed.ncbi.nlm.nih.gov/1997194
https://pubmed.ncbi.nlm.nih.gov/1997194