Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S. J. Haworth"'
Publikováno v:
Journal of Antimicrobial Chemotherapy. 36:35-41
The pharmacokinetics of meropenem were determined in healthy volunteers after intravenous injection over 5 min or iv infusion over 30 min. Five volunteers received meropenem 500 mg and six volunteers received 1000 mg. For both doses, administration o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214b4e920db803a7c84d0ff1faeb047e
https://doi.org/10.1093/jac/36.suppl_a.35
https://doi.org/10.1093/jac/36.suppl_a.35
Autor:
Harriette L. Nadler, Waheed Sheikh, K. L. Faulkner, M. Hutchison, D. H. Pitkin, P. J. Turner, S. J. Haworth
Publikováno v:
Journal of Antimicrobial Chemotherapy. 36:43-56
Meropenem body fluid and tissue concentration data from both published studies and samples obtained during efficacy evaluation have been compiled and presented according to a consistent format to facilitate comparison. The concentration data have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772fcd8411d732a1b9e637985a16ce6d
https://doi.org/10.1093/jac/36.suppl_a.43
https://doi.org/10.1093/jac/36.suppl_a.43
Publikováno v:
Xenobiotica. 23:1311-1323
1. The metabolism and pharmacokinetics of 14C-meropenem were studied in five volunteers who received 0.5 g (40 microCi) of the radiolabelled drug by i.v. infusion. 2. The maximum concentration of drug in plasma was 27 +/- 2 micrograms/ml (70 microM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7d7fad8ca7b5e3a68cef1a95daff3e
https://doi.org/10.3109/00498259309059441
https://doi.org/10.3109/00498259309059441
Five healthy volunteers and 18 patients with various degrees of renal impairment received 500 mg of meropenem intravenously as a 30-min infusion. Five dialysis patients were dosed 2 h prior to hemodialysis, and four of them were also dosed between he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b662216e66e112ad76c9b7cd7dbe192
https://europepmc.org/articles/PMC191616/
https://europepmc.org/articles/PMC191616/
Publikováno v:
European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 10(2)
Imipenem combined with cilastatin and meropenem was given as intravenous infusions of 1 g to eight young, healthy males on two separate occasions. Blood and urine samples were collected for up to 12 h. The terminal half-lives in plasma were 0.98 h an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d692409346cc0ae91c180af972f9e189
https://pubmed.ncbi.nlm.nih.gov/1864280
https://pubmed.ncbi.nlm.nih.gov/1864280
Publikováno v:
BMJ. 290:1775-1778
The incidence and characteristics of pulmonary haemorrhage in a series of 89 patients with systemic vasculitis were analysed. Pulmonary haemorrhage occurred in 32 of these patients and was associated with haemoptysis in all 32, alveolar shadowing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7459ff303b6595f9ad2b99234606d68c
https://doi.org/10.1136/bmj.290.6484.1775
https://doi.org/10.1136/bmj.290.6484.1775
Publikováno v:
QJM: An International Journal of Medicine.
In a number of patients recovery from infectious mononucleosis (IM) following primary Epstein Barr virus (EBV) infection, is complicated by the persistence of symptoms for months or years. Normally recovery from infectious mononucleosis is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1c0bd2378808fbe60b6bda75be7643
https://doi.org/10.1093/oxfordjournals.qjmed.a067944
https://doi.org/10.1093/oxfordjournals.qjmed.a067944
Publikováno v:
The Journal of antimicrobial chemotherapy. 24
Two human volunteer studies were performed with meropenem: a dose proportionality study of 0.25, 0.5 and 1.0 g and a probenecid interaction study. Six volunteers took part in each study. Meropenem was generally well tolerated: One volunteer was withd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db84890b7aee2e1ef0cbd47f0d6857bb
https://pubmed.ncbi.nlm.nih.gov/2808215
https://pubmed.ncbi.nlm.nih.gov/2808215
Autor:
C D Pusey, S J Haworth
Publikováno v:
Gut. 25(11)
A case of Wegener's granulomatosis is described, in which the presentation was blood stained mucus diarrhoea. Severe ileal, caecal, and rectal involvement improved rapidly after treatment with cyclophosphamide, azathioprine, and prednisolone. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f2818d89932ad9198eedbd407155c9
https://pubmed.ncbi.nlm.nih.gov/6500368
https://pubmed.ncbi.nlm.nih.gov/6500368
Publikováno v:
The Quarterly journal of medicine. 58(226)
In a number of patients recovery from infectious mononucleosis (IM) following primary Epstein Barr virus (EBV) infection, is complicated by the persistence of symptoms for months or years. Normally recovery from infectious mononucleosis is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::051d6855235d5195fb1041bacd45a605
https://pubmed.ncbi.nlm.nih.gov/3012622
https://pubmed.ncbi.nlm.nih.gov/3012622