Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S. J. Gorzinski"'
Publikováno v:
Pharmacology Biochemistry and Behavior. 36:683-689
Fischer 344 rats were exposed to 8000 ppm toluene vapor in an ‘abuse’ paradigm for 13 weeks to develop an animal model for ‘solvent neurotoxicity’. Exposures to toluene were multiple and short (15 to 35 min), adjusted according to tolerance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce5a154d39c52fadc346a4f1b1c5850
https://doi.org/10.1016/0091-3057(90)90274-l
https://doi.org/10.1016/0091-3057(90)90274-l
Publikováno v:
Journal of Toxicology and Environmental Health. 30:91-104
The chronic toxicity and oncogenicity of the herbicide picloram was studied in male and female Fischer 344 rats administered 0, 20, 60, or 200 mg/kg.d technical-grade picloram via their feed for 2 yr. A comprehensive set of in-life and clinical patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6300e9107c942365c3bbdb9f9702c30
https://doi.org/10.1080/15287399009531414
https://doi.org/10.1080/15287399009531414
Publikováno v:
Toxicological Sciences. 9:423-435
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97fa5ad055eb409217d13c0c80d0a7a9
https://doi.org/10.1093/toxsci/9.3.423
https://doi.org/10.1093/toxsci/9.3.423
Publikováno v:
Journal of Toxicology and Environmental Health. 20:367-377
The toxicity of orally administered technical-grade picloram was evaluated in male and female Fischer 344 rats. Dietary dose levels were up to 2000 mg/kg body weight (bw) X d for 2 wk, 500 mg/kg bw X d for 13 wk, or 200 mg/kg bw X d for 12 mo. Routin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca3419f3f46e6049aec01f812e96e7b
https://doi.org/10.1080/15287398709530990
https://doi.org/10.1080/15287398709530990
Acute, pharmacokinetic, and subchronic toxicological studies of 2,4-dichlorophenoxyacetic acid*1, *2
Publikováno v:
Fundamental and Applied Toxicology. 9:423-435
The single-dose oral LD50 values in Fischer 344 rats for technical-grade 2,4-dichlorophenoxyacetic acid (2,4-D), esters, and salts ranged from 553 mg/kg (isobutyl ester in females) to 1090 mg/kg (dimethylamine salt in males). The LD50 values for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a608f1f29f77df7d56dbcf730d900d97
https://doi.org/10.1016/0272-0590(87)90025-x
https://doi.org/10.1016/0272-0590(87)90025-x
Publikováno v:
Drug and chemical toxicology. 9(2)
The disposition of 14C-Hydroxypropyl methylcellulose (HPMC) with a viscosity of 2.25 centipoise was studied in male and female Sprague-Dawley rats following a single 500 mg/kg body weight gavage dose, or five consecutive daily doses. Recoveries for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e805b1c4ae250556637bc909f9b6f10
https://pubmed.ncbi.nlm.nih.gov/3757827
https://pubmed.ncbi.nlm.nih.gov/3757827
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 9(3)
The single-dose oral LD50 values in Fischer 344 rats for technical-grade, 2,4-dichlorophenoxyacetic acid (2,4-D), esters, and salts ranged from 553 mg/kg (isobutyl ester in females) to 1090 mg/kg (dimethylamine salt in males). The LD50 values for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff3a35833c50c8fd1ada35e670cbcefa
https://pubmed.ncbi.nlm.nih.gov/3692002
https://pubmed.ncbi.nlm.nih.gov/3692002
Publikováno v:
Neurotoxicology and teratology. 11(1)
Exposure to high concentrations of toluene vapors, or to intravenous o-cresol (a toluene metabolite) at about 0.9 mg/min, caused excitation of the somatosensory evoked potential (SEP) and EEG of Fischer 344 rats. SEP excitation was characterized by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f741b837046c79287f58d2b6f6f611f0
https://pubmed.ncbi.nlm.nih.gov/2818714
https://pubmed.ncbi.nlm.nih.gov/2818714
Autor:
J D, Burek, R R, Albee, J E, Beyer, T J, Bell, R M, Carreon, D C, Morden, C E, Wade, E A, Hermann, S J, Gorzinski
Publikováno v:
Journal of environmental pathology and toxicology. 4(5-6)
Groups of male and female Fischer 344 rats were administered acrylamide in their drinking water at 0, 0.05, 0.2, 1, 5, or 20 mg/kg/day for up to 93 days. Following the administration of acrylamide in the drinking water, male rats from each dose level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fe5f18b39a920e1e64bdf9513d6f35d
https://pubmed.ncbi.nlm.nih.gov/7217844
https://pubmed.ncbi.nlm.nih.gov/7217844
Autor:
S. J. Gorzinski, Kenneth M. Bodner, Roy A. Campbell, Keith A. Johnson, Richard W. Mast, Claude H. Wolf, Marvin A. Friedman
Publikováno v:
Toxicology and applied pharmacology. 85(2)
Male and female Fischer 344 rats were maintained on treated drinking water providing dosages of 0 (controls), 0.01, 0.1, 0.5, or 2.0 mg acrylamide/kg body wt/day for 2 years to assess the chronic toxicity and oncogenic potential of the chemical. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b9a53a6af5aaf1cb167f0c2e9631a9
https://pubmed.ncbi.nlm.nih.gov/3764902
https://pubmed.ncbi.nlm.nih.gov/3764902