Leflunomide interferes with pyrimidine nucleotide biosynthesis

Autor: J. T. Ransom, H. M. Cherwinski, N. Byars, J. M. Young, S. J. Ballaron, G. M. Nakano

Publikováno v: Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 44(8)

Leflunomide is an anti-inflammatory and immunosuppressive agent which blocks proliferation of transformed cells and mitogen stimulated normal lymphocytes but does not block T cell signalling mechanisms at antiproliferative concentrations. These prope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f6d87b1187a004fc74fd71e2813a3f
https://pubmed.ncbi.nlm.nih.gov/8581517

Asymmetric Ruthenium‐Catalyzed Hydroalkylation of Racemic Allylic Alcohols for the Synthesis of Chiral Amino Acid Derivatives.

Autor: Zhang, Xiaohui¹ (AUTHOR), Ma, Wei^1,2 (AUTHOR), Zhang, Jinyu¹ (AUTHOR), Tang, Weijun¹ (AUTHOR), Xue, Dong¹ (AUTHOR), Xiao, Jianliang³ (AUTHOR), Sun, Huaming¹ (AUTHOR), Wang, Chao¹ (AUTHOR) c.wang@snnu.edu.cn

Publikováno v: Angewandte Chemie. 6/27/2022, Vol. 134 Issue 26, p1-7. 7p.

Rapid Access to Multisubstituted Acrylamides from Cyclic Ketones via Palladium/Norbornene Cooperative Catalysis.

Autor: Wu, Zhao¹ (AUTHOR), Dong, Guangbin¹ (AUTHOR) gbdong@uchicago.edu

Publikováno v: Angewandte Chemie. 4/19/2022, Vol. 134 Issue 17, p1-6. 6p.

Development of trisubstituted thiophene-3-arboxamide selenide derivatives as novel EGFR kinase inhibitors with cytotoxic activity.

Autor: Makhal, Priyanka N., Sood, Anika, Shaikh, Arbaz Sujat, Dayare, Lahu N., Khatri, Dharmendra Kumar, Rao Kaki, Venkata

Publikováno v: RSC Medicinal Chemistry; Dec2023, Vol. 14 Issue 12, p2677-2698, 22p

Topical Antiedematogenic Activity of the Essential Oil of Psidium brownianum Mart. (OEPB) in Murine Ear Edema Models.

Autor: de Souza Sampaio R; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil., Brito Pereira Bezerra Martins AO; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil., Santos da Silva LY; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil., Torres Pessoa DR; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil., Ribeiro-Filho J; Oswaldo Cruz Foundation (Fiocruz), Fiocruz Ceará, 60180-900, Eusébio, CE, Brazil., de Araújo Delmondes G; Natural Products Pharmacology Laboratory, Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil., Bezerra Felipe CF; Molecular Biology Departament, Federal University of Paraiba (UFPB), Campus I - Jardim Cidade Universitária, 58059-900, João Pessoa, PB, Brazil., Alencar de Menezes IR; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil., Kerntopf MR; Laboratory of Pharmacology and Molecular Chemistry (LFQM), Department of Biological Chemistry, Regional University of Cariri (URCA), 63105-000, Crato, CE, Brazil.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2024 Apr; Vol. 21 (4), pp. e202400187. Date of Electronic Publication: 2024 Mar 20.