Zobrazeno 1 - 10
of 40
pro vyhledávání: '"S. I. Simon"'
Autor:
L. A. Cagle, A. L. Linderholm, L. M. Franzi, J. A. Last, S. I. Simon, N. J. Kenyon, R. W. Harper
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Introduction:Neutrophil transmigration is multifactorial and primarily driven by selectins and β2-integrins (CD11b/CD18), whose expression are dependent on the underlying stimulus. Ventilator-induced lung injury (VILI) results in a predominantly CD1
Externí odkaz:
https://doaj.org/article/7419572384ca48e08dcb5d9f0f6f0006
Autor:
T. Bechert, Johann Greil, S. Lugauer, S. I. Simon, H. P. Hümmer, J. P. Guggenbichler, M. Böswald, R. T. Carbon, A. Regenfus, U. Geitner
Publikováno v:
Infection. 27:S69-S73
Central venous long-term catheters offer reliable, large-lumen vascular access with high flow rates for delivery of nutrition or for cell-containing infusions and perfusions. Catheter-associated infections (CAI) pose the greatest threat to such vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb762332536ff3e2e0257998b116ee5
https://doi.org/10.1007/bf02561623
https://doi.org/10.1007/bf02561623
Autor:
A R Burns, D C Walker, E S Brown, L T Thurmon, R A Bowden, C R Keese, S I Simon, M L Entman, C W Smith
Publikováno v:
The Journal of Immunology. 159:2893-2903
Since macromolecular permeability between endothelial cells is regulated by tight junctions (zonula occludens), we wished to determine whether they also regulate neutrophil transendothelial migration. HUVEC monolayers, a commonly used model for study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5119954d41824aa4991a3ece0eab6a96
https://doi.org/10.4049/jimmunol.159.6.2893
https://doi.org/10.4049/jimmunol.159.6.2893
Autor:
B W McIntyre, D G Woodside, D A Caruso, D K Wooten, S I Simon, S Neelamegham, J K Revelle, P Vanderslice
Publikováno v:
The Journal of Immunology. 158:4180-4186
The cyclic hexapeptide CWLDVC (TBC 772) is an antagonist of alpha4 integrins and a potent inhibitor of lymphocyte interactions with fibronectin, vascular cell adhesion molecule-1, and muscosal vascular addressin cell adhesion molecule-1 (MAdCAM-1). A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48645af5c27602f5f9296aa2872bc309
https://doi.org/10.4049/jimmunol.158.9.4180
https://doi.org/10.4049/jimmunol.158.9.4180
Publikováno v:
The Journal of Immunology. 158:367-375
Neutrophil emigration through endothelial cells under shear flow involves several adhesion processes including cell rolling, arrest, and transmigration. Rolling is mediated by selectins, while arrest and transmigration both require activated CD18 int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc74f113ec05d3aaed4861572dc08bed
https://doi.org/10.4049/jimmunol.158.1.367
https://doi.org/10.4049/jimmunol.158.1.367
Publikováno v:
The Journal of Immunology. 155:1502-1514
Emigration of leukocytes at sites of inflammation is initiated by the selectin family of carbohydrate-binding adhesion molecules. Molecular crossbridges initiate rolling of cells along the vascular endothelium where chemokines such as IL-8 and platel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c91550b2a70e242360fb9415387e87
https://doi.org/10.4049/jimmunol.155.3.1502
https://doi.org/10.4049/jimmunol.155.3.1502
Publikováno v:
Blood. 83:3303-3311
Human neutrophils are primed in the presence of complexes of lipopolysaccharide (LPS) with its serum binding protein (LBP) in a manner dependent on CD14. Cellular consequences of priming include increased responsiveness, the upregulation of surface p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959ec6476b1c8abe903637af17032c90
https://doi.org/10.1182/blood.v83.11.3303.3303
https://doi.org/10.1182/blood.v83.11.3303.3303
Publikováno v:
The Journal of Immunology. 152:1385-1393
We have recently reported that neutrophil aggregation is dependent on both L-selectin and the beta 2-integrin Mac-1, raising the possibility that carbohydrate interactions play a role in aggregation. We used mono- and polysaccharides known to inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b15a46e6841032cd8320a408597c1bd3
https://doi.org/10.4049/jimmunol.152.3.1385
https://doi.org/10.4049/jimmunol.152.3.1385
Publikováno v:
Blood. 82:1097-1106
We have recently found that antibodies to L-selectin, the homing receptor on neutrophils, are as effective as those to beta 2-integrin at blocking formyl peptide-stimulated aggregation. Therefore, we investigated the requirements for expression of L-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44dcf598c54b6de21cc86f6167cd103d
https://doi.org/10.1182/blood.v82.4.1097.1097
https://doi.org/10.1182/blood.v82.4.1097.1097
Publikováno v:
The Journal of Immunology. 149:2765-2771
Neutrophil aggregation in response to formyl peptide was analyzed in blood and isolated cells by fluorescence flow cytometry. The isolated leukocyte aggregates and the leukocytes in blood were identified with the vital nucleic acid stain LDS-751. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b575d9a92c9519b59f84542438a21b5
https://doi.org/10.4049/jimmunol.149.8.2765
https://doi.org/10.4049/jimmunol.149.8.2765