Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S. I. Michael"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 1(12)
One strategy used for gene therapy of cancer is molecular chemotherapy. This approach is based on selective expression of an encoded toxin in cancer cells to achieve their eradication. One potential advantage of this strategy derives from a phenomeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81ad385b3b122338bb5c6a2374a12622
https://pubmed.ncbi.nlm.nih.gov/9815958
https://pubmed.ncbi.nlm.nih.gov/9815958
Publikováno v:
Gene therapy. 2(9)
A major concern associated with the use of recombinant adenoviral vectors is that viral receptors are found on the surface of many cell types and systemic in vivo delivery of the viral vector could result in uncontrolled and widespread expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44d8a96bf3e945d361b19000114298d8
https://pubmed.ncbi.nlm.nih.gov/8548556
https://pubmed.ncbi.nlm.nih.gov/8548556
Autor:
S I, Michael, D T, Curiel
Publikováno v:
Gene therapy. 1(4)
Gene transfer to eukaryotic cells may be accomplished by capitalizing on endogenous cellular pathways of macromolecular transport. In this regard, molecular conjugate vectors have been developed which deliver DNA via the receptor-mediated endocytosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2f6304d545fb16d944e664217138b4e
https://pubmed.ncbi.nlm.nih.gov/7584085
https://pubmed.ncbi.nlm.nih.gov/7584085
Publikováno v:
The Journal of biological chemistry. 268(10)
Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7871cd73df700e89bbedde2bc8fd0037
https://pubmed.ncbi.nlm.nih.gov/8463214
https://pubmed.ncbi.nlm.nih.gov/8463214
Molecular conjugate vectors may be constructed that accomplish high efficiency gene transfer by the receptor-mediated endocytosis pathway. In order to mediate escape from lysosomal degradation, we have incorporated adenoviruses into the functional de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b197c5fd8311efc6d3304689a61e5a96
