Zobrazeno 1 - 10
of 44
pro vyhledávání: '"S. Hirschel-Scholz"'
Autor:
Jean-Hilaire Saurat, Jean-Dominique Vassalli, Joachim Huarte, S Hirschel-Scholz, André-Pascal Sappino, Dominique Belin
Publikováno v:
Journal of Clinical Investigation, Vol. 88, No 4 (1991) pp. 1073-1079
To assess the postulated role of plasminogen activation in tumor invasion, we have investigated the cellular sites of synthesis for urokinase-type (uPA) and tissue-type (tPA) plasminogen activators and their inhibitors (PAI-1 and PAI-2) in two human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026d2072df1d45692b1af2018bb0da71
https://doi.org/10.1172/jci115406
https://doi.org/10.1172/jci115406
Publikováno v:
Journal of Clinical Investigation. 76:1851-1856
Hypocalcemia has been observed in patients receiving WR-2721 [S-,2-(3-aminopropylamino)-, ethylphosphorothioic acid]. WR-2721 is a compound that, after being dephosphorylated, provides protection of normal tissues against radio- and chemotherapy. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb7c284d54fd76f4578dc138778db25
https://doi.org/10.1172/jci112178
https://doi.org/10.1172/jci112178
Autor:
Virginia C. Fiedler, Henry H. Roenigk, D. Salomon, R. Müller, Anders Vahlquist, John J. Voorhees, Raj Kumar, R. Happle, G.L. Peck, J.-H. Saurat, Christa Fiedler-Nagy, B. Melnik, Ursula M. Ney, Michael T. Goldfarb, Jack P. Lawson, Peter M. Elias, G. Siegenthaler, W.J. Cunliffe, R. Stadler, Gary L. Peck, Oksana Holian, Maria Ponec, Ola Rollman, Alan R. Shalita, H. Traupe, Bernd Thiele, Barbara H. Wittreich, C.E. Orfanos, U. Bros, Ann F. Welion, Anton M. Jetten, David P. Bloxham, M. Detmar, H. Gollnick, Donald Westmacott, S. Hirschel-Scholz, J.F.B. Norris, John W. Coffey, Santosh Nigam, H. Vahlquist, D.R. Sherman, Alex Georgiadis, Ian J. Ball, Gustav Mahrle, Joseph F. McGuire, G. Plewig, Charles Ellis, P.C.M. van de Kerkhof, Jr. Roenigk H.H., Johannes Boonstra, Roger P. Hill, F. Chytil, William C. Hope, Lourdes Tamayo, Ramón Ruiz-Maldonado
Publikováno v:
Dermatology. 175:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01b340912864d0d2d8a539012db4a993
https://doi.org/10.1159/000248848
https://doi.org/10.1159/000248848
Publikováno v:
Mineral and electrolyte metabolism. 14(2-3)
Recently, a radio-, and chemoprotective drug, WR-2721 (S-2-[3-aminopropylamino]-,ethylphosphorothioic acid) proved to be a potent inhibitor of parathyroid hormone (PTH) secretion. In human subjects, it not only decreased plasma Ca, but also induced a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e6fb678de8f7e521b904e81feb1ca945
https://pubmed.ncbi.nlm.nih.gov/2837628
https://pubmed.ncbi.nlm.nih.gov/2837628
Publikováno v:
Schweizerische medizinische Wochenschrift. 113(16)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19009dc0a7e6a4f93cef9b1d3be3f4df
https://pubmed.ncbi.nlm.nih.gov/6867651
https://pubmed.ncbi.nlm.nih.gov/6867651
Publikováno v:
Phosphate and Mineral Homeostasis ISBN: 9781468452082
Recent studies suggest that the organic phosphorothioate WR-2721 could be a useful drug in the treatment of hypercalcemia, particularly in relation with disorders of parathyroid hormone (PTH) homeostasis (1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a9c3907ed8e224345abc43dc632ea5
https://doi.org/10.1007/978-1-4684-5206-8_45
https://doi.org/10.1007/978-1-4684-5206-8_45
Publikováno v:
The Journal of clinical investigation. 78(1)
The Rice-500 Leydig cell tumor (LCT) in Fischer rats is a model of humoral hypercalcemia of malignancy (HHM). In this model, the elevation of plasma calcium (Ca) does not result merely from an increased bone resorption, but also from an enhanced tubu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f278e51218846665cf68bcb5dd51b5
https://pubmed.ncbi.nlm.nih.gov/3013941
https://pubmed.ncbi.nlm.nih.gov/3013941
Publikováno v:
Bone. 8
Hypercalcemia results from an imbalance between the fluxes of calcium (Ca) entering and leaving the extracellular space. The two most important influxes are the net intestinal Ca absorption and the net skeletal Ca resorption, whereas the renal excret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80b2fc5814174f73450e930af21160ab
https://pubmed.ncbi.nlm.nih.gov/2825740
https://pubmed.ncbi.nlm.nih.gov/2825740
Publikováno v:
Clinical endocrinology. 23(3)
SUMMARY WR-2721 is an organic thiophosphate, known as a radioprotective agent, which also inhibits parathyroid hormone (PTH) secretion and reduces the plasma calcium level in euparathyroid animals and human subjects. In this study we present evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdd561f89a7afa2e371b7db3227ffc8
https://pubmed.ncbi.nlm.nih.gov/3000652
https://pubmed.ncbi.nlm.nih.gov/3000652
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