Zobrazeno 1 - 10
of 70
pro vyhledávání: '"S. Henzgen"'
Publikováno v:
Experimental and Toxicologic Pathology. 48:255-263
Ultrastructural changes of knee articular cartilage in C57B1/6 mice were studied in the course of antigen-induced arthritis by means of scanning and transmission electron microscopy. First damages of the cartilage surface were seen one hour after art
Publikováno v:
Rheumatology International. 16:23-28
The pyridinium crosslinks are important and definite biomarkers of mature hard tissue collagen degradation. A gradient ion-paired reversed-phase high-performance liquid chromatographic method was used for the simultaneous determination of both crossl
Publikováno v:
Experimental and Toxicologic Pathology. 46:383-388
Antigen-induced arthritis in guinea pigs was used as a model to investigate the pathogenic mechanisms responsible for cartilage destruction in chronic joint inflammation. The activation of macrophages, their effects on cartilage metabolism, and the d
Publikováno v:
Experimental Pathology. 40:35-44
The chronicity of the antigen-induced arthritis is characterized as dependent on the development of cell-mediated immunity to the antigen, but the exact mechanisms underlying are unclear. We have evidenced decreased suppressor and increased helper ce
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 53(5)
Objective and design:Sex hormones have immunomodulatory properties and may play an important role in the pathogenesis of autoimmune diseases like rheumatoid arthritis (RA). This study sought to examine the effects of the natural weak androgen dehydro
Publikováno v:
Agents and Actions. 41:96-98
The effects of the T-cell-directed immunosuppressant cyclosporin A (CsA) on the development of antigen-induced arthritis (AIA) in rats as well as on cytokine levels in synovial fluid and serum were determined. The treatment with CsA effectively inhib
Publikováno v:
Agents and Actions. 38:C95-C97
Long-term treatment with natural and synthetic thymic and splenic peptides as well as cyclosporin A inhibited the development of antigen-induced arthritis in rats. This was demonstrated by decreased joint swelling and reduced degree of macroscopicall
Autor:
Rolf Bräuer, Raimund W. Kinne, Ralf Surber, S. Henzgen, Peter K. Petrow, Jutta Simon, Gesa Kleinstäuber
Publikováno v:
Journal of autoimmunity. 17(2)
Local and systemic macrophage activation was examined during the course of monoarticular murine antigen-induced arthritis (AIA), induced by systemic immunization and subsequent local induction. The levels of tumour necrosis factor-alpha (TNF-alpha),
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 49(8)
Objective: To investigate the effects of clodronate on clinical disease activity, inflammatory alterations and cartilage destruction, periarticular and axial bone volume and bone turnover in chronic antigen-induced arthritis (AIA; day 28).¶Methods:
Autor:
K. Thoss, Rolf Bräuer, Peter Oelzner, B. Wünsche, G. Hersmann, S. Henzgen, K. Abendroth, Raimund W. Kinne
Publikováno v:
Clinical immunology (Orlando, Fla.). 90(1)
The long-term effects of acutely administered clodronate (free or liposome-encapsulated) on periarticular bone mass and bone turnover were investigated in chronic antigen-induced arthritis (AIA; day 28). Wistar rats were treated intraperitoneally at