Zobrazeno 1 - 10
of 27
pro vyhledávání: '"S. Halleran"'
Autor:
S. Halleran, J. W. Quail, S.J. Hayes, S.A. Arpin, Theresa M. Allen, Jonathan R. Dimmock, M Hetherington, J Baizarini, J. P. Stables, Praveen Kumar, Ercin Erciyas, E. De Clercq, U. Pugazhenthi
Publikováno v:
European Journal of Medicinal Chemistry. 32:583-594
Summary A number of arylazophenols 1 were converted into the corresponding mono Mannich bases 2 from which two quaternary salts 3a,b and an ester 3c were prepared. A series of bis Mannich bases 4 were also synthesized. The angles (θ) made between on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09f653b9156bcba6747e27aa9d625326
https://doi.org/10.1016/s0223-5234(97)83284-9
https://doi.org/10.1016/s0223-5234(97)83284-9
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adcd7a572ae15a70c461f3e8db483a73
https://doi.org/10.1002/chin.199530090
https://doi.org/10.1002/chin.199530090
Publikováno v:
ChemInform. 27
A number of Mannich bases of alicyclic ketones containing one and two basic centres were prepared in order to evaluate the theory of sequential cytotoxicity and develop structure-activity relationships in these series of compounds. The compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d29dba3805f436c19a6db2c6dd501f1f
https://doi.org/10.1002/chin.199607108
https://doi.org/10.1002/chin.199607108
Autor:
S. Halleran, Piyush Kumar, Jonathan R. Dimmock, E. De Clercq, G. Y. Kao, Todd M. Allen, Jan Balzarini
Publikováno v:
ChemInform. 28
A number of 1-aryl-1-penten-3-ones 1 and related Mannich bases 2 were synthesized and converted either directly or indirectly to the corresponding biscarbohydrazones 3 and 4. Reaction of representative unsaturated ketones with thiocarbohydrazide led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb0b84f5528ff2dd4a5166efa666a3b
https://doi.org/10.1002/chin.199727084
https://doi.org/10.1002/chin.199727084
Autor:
S. Halleran, Sarvesh C. Vashishtha, J. Balzarani, Cheryl Santos, Jonathan R. Dimmock, Todd M. Allen, J. Szydlowski, E. De Clercq
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4be5eba7f97456baeebc8c71d120343
https://doi.org/10.1002/chin.200132141
https://doi.org/10.1002/chin.200132141
Autor:
S C, Vashishtha, T M, Allen, S, Halleran, J, Szydlowski, C L, Santos, E, De Clercq, J, Balzarani, J R, Dimmock
Publikováno v:
Die Pharmazie. 56(5)
A previous investigation revealed that various 4-aryl-3-arylcarbonyl-1-ethyl-4-piperidinols and related vinylogs were cytotoxic to both murine and human tumour cell lines. In particular, 1a and 2a were identified as useful prototypic molecules. Struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::620a40150aec4e6d76ac5127d1a18ed3
https://pubmed.ncbi.nlm.nih.gov/11400554
https://pubmed.ncbi.nlm.nih.gov/11400554
Publikováno v:
Die Pharmazie. 52(3)
A number of 1-aryl-1-penten-3-ones 1 and related Mannich bases 2 were synthesized and converted either directly or indirectly to the corresponding biscarbohydrazones 3 and 4. Reaction of representative unsaturated ketones with thiocarbohydrazide led
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bab6e7e529d50488c82f16ca4c4fc09
https://pubmed.ncbi.nlm.nih.gov/9109166
https://pubmed.ncbi.nlm.nih.gov/9109166
Publikováno v:
Die Pharmazie. 50(10)
A number of Mannich bases of alicyclic ketones containing one and two basic centres were prepared in order to evaluate the theory of sequential cytotoxicity and develop structure-activity relationships in these series of compounds. The compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1702bf584a2865499c64c8aec778a6ef
https://pubmed.ncbi.nlm.nih.gov/7501688
https://pubmed.ncbi.nlm.nih.gov/7501688
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