Zobrazeno 1 - 10
of 27
pro vyhledávání: '"S. H. van der Burg"'
Autor:
S. J. Santegoets, C. L. Duurland, E. S. Jordanova, J. J. van Ham, I. Ehsan, S. L. van Egmond, M. J. P. Welters, S. H. van der Burg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Regulatory T cells (Tregs) may comprise different subsets allowing them to efficiently suppress different types of effector T cells. In this study, we show that high numbers of both conventional and Tbet co-expressing Foxp3hi Tregs accumulat
Externí odkaz:
https://doaj.org/article/62868b7ab4e84d2c8edcadb20c09e374
Autor:
S. J. A. M. Santegoets, A. F. de Groot, E. M. Dijkgraaf, A. M. Carnaz Simões, V. E. van der Noord, J. J. van Ham, M. J. P. Welters, J. R. Kroep, S. H. van der Burg
Publikováno v:
OncoImmunology, Vol 7, Iss 8 (2018)
Epithelial ovarian cancer (EOC) may cause abnormal blood levels of leukocytes. This paraneoplastic manifestation is associated with a worse response to therapy and shorter survival. To understand the complexity and nature of these leukocytes, we diss
Externí odkaz:
https://doaj.org/article/f4b6784697f04c0297d742904ad36aca
Autor:
H. van Meir, R. A. Nout, M. J. P. Welters, N. M. Loof, M. L. de Kam, J. J. van Ham, S. Samuels, G. G. Kenter, A. F. Cohen, C. J. M. Melief, J. Burggraaf, M. I. E. van Poelgeest, S. H. van der Burg
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
New treatments based on combinations of standard therapeutic modalities and immunotherapy are of potential use, but require a profound understanding of immune modulatory properties of standard therapies. Here, the impact of standard (chemo)radiothera
Externí odkaz:
https://doaj.org/article/9ab1477d33ed4379aebc6f6b01ce1a4c
Autor:
G, de Jong, L, Bartels, M, Kedde, E M E, Verdegaal, M A, Gillissen, S E, Levie, M G, Cercel, S E, van Hal-van Veen, C, Fatmawati, D, van de Berg, E, Yasuda, Y B, Claassen, A Q, Bakker, S H, van der Burg, R, Schotte, J, Villaudy, H, Spits, M D, Hazenberg, P M, van Helden, K, Wagner
Publikováno v:
Cancer immunology, immunotherapy : CII. 70(6)
Targeted cancer therapy with monoclonal antibodies has proven successful for different cancer types but is limited by the availability of suitable antibody targets. CD43s, a unique sialylated form of CD43 expressed by hematologic malignancies, is a r
Autor:
H, Van Meir, I J, du Burck, M L, de Kam, M J P, Welters, S H, van der Burg, J B M Z, Trimbos, C D, de Kroon, M I E, van Poelgeest
Publikováno v:
European journal of gynaecological oncology. 38(1)
To investigate prognostic factors in patients with recurrent cervical cancer after treatment of early-stage disease in order to identify high-risk patients who might benefit from alternative treatment strategies.The authors retrospectively analyzed c
Publikováno v:
The Journal of Immunology. 159:5545-5549
Bispecific Abs (BsAb) represent a novel format of immunotherapy, recognizing immune effector cells (e.g., T cells), on the one hand, and target cells (e.g., tumor cells), on the other hand. To be successful, cross-linking of the two cell types is nec
Autor:
E M G, van Esch, B, Tummers, V, Baartmans, E M, Osse, N, Ter Haar, M D, Trietsch, B W J, Hellebrekers, C A G, Holleboom, H T C, Nagel, L T, Tan, G J, Fleuren, M I E, van Poelgeest, S H, van der Burg, E S, Jordanova
Publikováno v:
International journal of cancer. 135(4)
Immunotherapy of usual vulvar intraepithelial neoplasia (uVIN) is promising; however, many patients still fail to show clinical responses, which could be explained by an immune escape through alterations in human leukocyte antigen (HLA) expression. T
Autor:
P J, de Vos van Steenwijk, T H, Ramwadhdoebe, R, Goedemans, E M, Doorduijn, J J, van Ham, A, Gorter, T, van Hall, M L, Kuijjer, M I E, van Poelgeest, S H, van der Burg, E S, Jordanova
Publikováno v:
International journal of cancer. 133(12)
One of the hallmarks of cancer is the influx of myeloid cells. In our study, we investigated the constitution of tumor-infiltrating myeloid cells and their relationship to other tumor-infiltrating immune cells, tumor characteristics and the disease-s
Publikováno v:
The Journal of Immunology. 156:3308-3314
The impact of the MHC class I peptide binding stability on the immunogenicity of particular peptide Ags in class I-restricted cytotoxic T lymphocyte responses is not clearly established. Therefore, we have determined the dissociation rate of each pep
Autor:
E. C. Hagen, F. J. Van Der Woude, S. H. Van Der Burg, C. J. M. Melief, B. E. P. B. Ballieux, M. R. Daha
Publikováno v:
clinical & experimental immunology
SUMMARY Despite the well described infiltration of cells of the cellular immune system in vasculitic lesions and the granuloma formation in patients with WG, the role of T cell-mediated autoimmunity in WG is not clear. Reports of T cell proliferation