Zobrazeno 1 - 10 of 14 pro vyhledávání: '"S. H. Safe"'
1
Metabolism and bacterial mutagenicity of binary mixtures of benzo(a)pyrene and polychlorinated aromatic hydrocarbons
Autor: K. C. Donnelly, K. W. Brown, C. S. Anderson, G. C. Barbee, S. H. Safe, K. E. Mortlemans
Publikováno v: Environmental and Molecular Mutagenesis. 16:238-245
The results of both the Salmonella/microsome mutagenicity assay and high-performance liquid chromatography (HPLC) analysis were used to evaluate the interactions of binary mixtures of benzo(a)pyrene (BAP) and several different polychlorinated aromati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacdc02f3b774c9af0d9de0c2fce32e1
https://doi.org/10.1002/em.2850160404
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2
Comparative 32P-postlabeling analysis of exogenous and endogenous DNA adducts in mouse skin exposed to a wood-preserving waste extract, a complex mixture of polycyclic and polychlorinated chemicals
Autor: K, Randerath, G D, Zhou, E, Randerath, S H, Safe, K C, Donnelly
Publikováno v: Environmental and molecular mutagenesis. 29(4)
Wood preserving waste (WPW) sites contain numerous toxic compounds, including phenols, polycyclic aromatic hydrocarbons (PAHs), polychlorinated dibenzodioxins, and dibenzofurans. Previous in vitro and in vivo 32P-postlabeling studies showed the induc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2815f2ff0aa5c2e1401391dd534dcf9d
https://pubmed.ncbi.nlm.nih.gov/9212788
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3
Organochlorine exposure and risk for breast cancer
Autor: S H, Safe, T, Zacharewski
Publikováno v: Progress in clinical and biological research. 396
Organochlorine industrial compounds, combustion products and pesticides have been widely identified in the environment and residues have been detected in extracts prepared from fish, wildlife, human tissues as well as human milk and serum. Many of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::418df0f8df0368255e1f465407912d70
https://pubmed.ncbi.nlm.nih.gov/9108595
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4
Atypical cytochrome P450 induction profiles in glomerular mesangial cells at the mRNA and enzyme level. Evidence for CYP1A1 and CYP1B1 expression and their involvement in benzo[a]pyrene metabolism
Autor: R C, Bowes, A R, Parrish, M A, Steinberg, K L, Willett, W, Zhao, U, Savas, C R, Jefcoate, S H, Safe, K S, Ramos
Publikováno v: Biochemical pharmacology. 52(4)
Recent studies in this laboratory have shown that benzo[a]pyrene (BaP) modulates growth factor-related gene expression and proliferation of renal glomerular mesangial cells (GMCs) in vitro. Because many of the toxic and biochemical effects of this po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5e67fa0048ff0442292b207e72866e1
https://pubmed.ncbi.nlm.nih.gov/8759031
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6
Indolo[3,2-b]carbazole: a dietary-derived factor that exhibits both antiestrogenic and estrogenic activity
Autor: H, Liu, M, Wormke, S H, Safe, L F, Bjeldanes
Publikováno v: Journal of the National Cancer Institute. 86(23)
Background Indole-3-carbinol (I3C) and related compounds have been identified in vegetables of the Brassica genus. I3C and its acid-derived condensation product, indolo[3,2-b]carbazole (ICZ), bind to the aryl hydrocarbon (Ah) receptor and induce CYP1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac38f8d9cdcc894775b5f23ce1cfa5e9
https://pubmed.ncbi.nlm.nih.gov/7966405
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7
Gap junctions in myometrial cell cultures: evidence for modulation by cyclic adenosine 3':5'-monophosphate
Autor: H D, Dookwah, R, Barhoumi, T R, Narasimhan, S H, Safe, R C, Burghardt
Publikováno v: Biology of reproduction. 47(3)
Primary cultures of myometrial cells from juvenile rats, continuous cultures maintained by serial passage, and a pSV3neotransfected myometrial cell line were established and utilized for the study of development and modulation of gap junctional inter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1dfd6a9e92d183b592d3f1d76f846ca
https://pubmed.ncbi.nlm.nih.gov/1324745
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10
Influences of different polychlorinated biphenyls on cytocidal, mitoinhibitory, and nodule-selecting activities of N-2-fluorenylacetamide in rat liver
Autor: M A, Hayes, E, Roberts, S H, Safe, E, Farber, R G, Cameron
Publikováno v: Journal of the National Cancer Institute. 76(4)
The influences of different polychlorinated biphenyl (PCB) isomers and congeners on distinct hepatotoxic responses to the hepatocarcinogen N-2-fluorenylacetamide [(2-FAA) CAS: 53-96-3] were examined in F344 rats. Cytocidal toxicity of 2-FAA (25-400 m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d4e6955968b850de3b6e1b206a114f41
https://pubmed.ncbi.nlm.nih.gov/2870208
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