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pro vyhledávání: '"S. H. Randell"'
Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus
Autor:
S. J. Anthony, K. Gilardi, V. D. Menachery, T. Goldstein, B. Ssebide, R. Mbabazi, I. Navarrete-Macias, E. Liang, H. Wells, A. Hicks, A. Petrosov, D. K. Byarugaba, K. Debbink, K. H. Dinnon, T. Scobey, S. H. Randell, B. L. Yount, M. Cranfield, C. K. Johnson, R. S. Baric, W. I. Lipkin, J. A. K. Mazet
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
ABSTRACT The evolutionary origins of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) are unknown. Current evidence suggests that insectivorous bats are likely to be the original source, as several 2c CoVs have been described from vario
Externí odkaz:
https://doaj.org/article/931f35c9c32a4ca38e5bc6819a478d09
Publikováno v:
Otolaryngology–Head and Neck Surgery. 116:308-316
The mechanisms that regulate mucin release in chronic otitis media with effusion, a leading cause of hearing loss in children, remain largely unknown. We developed an animal model using Sprague-Dawley rats to determine the factors responsible for muc
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 266:L296-L307
The purpose of these studies was to determine whether both basal and secretory rat tracheal epithelial (RTE) cells served as multipotent epithelial progenitors and whether both cell types gave rise to a similar "poorly differentiated" cell during the
Autor:
S. H. Randell
Publikováno v:
Chest. 101:11S-16
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 212(4)
Normal lung morphogenesis and cytodifferentiation require interactions between epithelium and mesenchyme. We have previously shown that distal lung mesenchyme (LgM) is capable of reprogramming tracheal epithelium (TrE) from day 13-14 rat fetuses to b
Publikováno v:
Methods in cell biology. 47
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 4(12)
It has been previously reported (R. W. Steigerwalt et al., Mol. Carcinog., 5:32-40, 1992) that primary cultures of rat tracheal epithelial (RTE) cells and immortalized RTE cell lines produce three mRNA transcripts [2.5, 1.9, 1.4 kilobases (kb)] which
Publikováno v:
The American journal of physiology. 260(6 Pt 1)
During the last stages of intrauterine growth, remarkable changes occur in the alveolar epithelium that include cellular differentiation and increased production of surfactant lipid and apoprotein. We made morphometric measurements of type II cell ch
Publikováno v:
The American review of respiratory disease. 133(5)
We have employed three-dimensional reconstructions and cytochemistry to analyze nonciliated bronchiolar epithelial (Clara) cells from rat lungs. We identified a previously unreported ovoid granule type, which was characterized by its relative electro